Abstract: A sampling kit for tissue including a reaction chamber and a sampling device configured for mounting in the reaction chamber and providing a reaction volume defined between the base of the reaction chamber and the sampling device. The sampling device has a proximal handling portion and a distal scraping portion comprising a scraping formation configured to collect a sample of tissue when the distal scraping portion is rubbed against a surface of the tissue. The sampling device comprises an internal lumen configured for the supply of reaction liquid from a distal end of the tissue sampling device to the reaction volume via a distal aperture disposed in the distal scraping portion when the tissue sampling device is mounted in the reaction chamber. An automated high-throughput sampling and indexing system is also described.

Abstract: The present disclosure relates to an aerosol delivery device and system e.g. a smoking substitute device and system. In particular an aerosol delivery device comprising: a movement detection unit configured to detect a movement of the device; a power source having a charge status; and a feedback element configured to provide feedback based on the charge status of the power source wherein the feedback element provides feedback in response to a movement of the device detected by the movement detection unit.

Abstract: A cable enclosure is provided herein. The cable enclosure includes a tray including first and second power conductor terminal blocks, a first protective lid over the first power conductor terminal block, and a second protective lid over the second power conductor terminal block.

Abstract: A smoking substitute device is configured to record and store user data that is generated during operation of the device. Analyzing the user data can provide the user with useful information regarding their use of the smoking substitute device as well as useful information regarding the operational performance of the device. Typically, the analysis of the data would be conducted by a remote device and the smoking substitute device therefore includes a communication interface to connect and communicate with the remote device. The smoking substitute device and method of managing the smoking substitute device allows user data to be deleted from the device upon identification of a reset operation wherein the reset operation is able to be triggered from the connected remote device and/or the smoking substitute device. Providing a function to delete user data upon identification of a reset operation provides the user with some control over their information.

Abstract: Disclosed herein are compositions, constructs, cassettes, vectors, cells, nucleic acids, peptides, proteins, protocols and methods for reducing cholesterol and lipid buildup in mammalian subjects, via gene and/or cell therapeutic treatments. In many embodiments, the disclosed compositions, cells, constructs, cassettes, vectors, nucleic acids, peptides, proteins, protocols and methods may help to reduce lipid levels in mammals. In one embodiment, the disclosed compositions, cells, constructs, cassettes, vectors, nucleic acids, peptides, proteins, protocols and methods are useful in reducing lipid build-up, especially cholesterol, in liver cells.

Abstract: The present disclosure relates to an aerosol delivery device and system, e.g., a smoking substitute device and system. In particular an aerosol delivery device, comprising: a source of power, for providing power to a heater; a first charging connection, for charging the source of power, located at a first end of the aerosol delivery device; and a second charging connection, for charging the source of power.

Abstract: A smoking substitute device is configured to record and store user data that is generated during operation of the device. Analyzing the user data can provide the user with useful information regarding their use of the smoking substitute device as well as useful information regarding the operational performance of the device. Typically, the analysis of the data would be conducted by a remote device and the smoking substitute device therefore includes a communication interface to connect and communicate with the remote device. The smoking substitute device and method of managing the smoking substitute device allows user data to be deleted from the device upon identification of a reset operation wherein the reset operation is able to be triggered from the connected remote device and/or the smoking substitute device. Providing a function to delete user data upon identification of a reset operation provides the user with some control over their information.

Abstract: Structures for a through-silicon via and methods of forming a structure for a through-silicon via. The structure includes a substrate having a trench and surfaces that border the trench. The structure further includes a through-silicon via having a layer inside the trench. The layer is in direct contact with the surfaces of the substrate.

Abstract: Example embodiments describe an optical line terminal (OLT) configured to communicate in a point-to-multipoint optical network with optical network units (ONUs); where the OLT and a respective ONU share a set of shared keys. The OLT configured to perform receiving, from a respective ONU, at least one identifier encrypted according to a preconfigured encryption algorithm and a preconfigured key; wherein the at least one identifier is characteristic for the respective ONU. The OLT configured to perform decrypting the at least one received identifier according to the preconfigured encryption algorithm and the preconfigured key; and determining at least one shared key based on the at least one decrypted identifier.

Abstract: Described herein is a system for enabling a user to perform complex goals using multiple skills/applications of an intelligent assistant device. Skills may register as consumers of an action or providers of an action, and the consumer skills may be configured to invoke provider skills to perform actions. The system receives a request to perform an action from a skill along with some action data. The system validates the action data, selects another skill to perform the action, and forwards the request to the selected skill to perform the action.

Abstract: The present disclosure relates to an aerosol delivery device (102) comprising a communication interface (124) configured to communicate with a mobile device (300), a user interface (160) configured to receive a user input sequence, and a memory (122) configured to store an access key (166). The device (102) further comprises a controller (120) configured to compare a user input sequence received by the user interface (160) with the stored access key (166). and control communication between the aerosol delivery device (102) and the mobile device (300) based on the comparison. Also disclosed is an access system for managing access to an aerosol delivery device. The system comprises a server (400) configured to store a server key (404) that corresponds to the access key (166) of the aerosol delivery device (102), the server (400) further configured to receive user verification data. determine whether the user verification data meets a user verification criteria. and provide the server key (404). upon request.

Abstract: A cable enclosure is provided herein. The cable enclosure includes a tray including first and second power conductor terminal blocks, a first protective lid over the first power conductor terminal block, and a second protective lid over the second power conductor terminal block.

Abstract: Described herein is a system for enabling a user to perform complex goals using multiple skills/applications of an intelligent assistant device. Skills may register as consumers of an action or providers of an action, and the consumer skills may be configured to invoke provider skills to perform actions. The system receives a request to perform an action from a skill along with some action data. The system validates the action data, selects another skill to perform the action, and forwards the request to the selected skill to perform the action.

Abstract: Hybrid enclosures for power and optical fiber are provided herein. A hybrid enclosure includes a power conductor terminal and an optical fiber splice area that are in separate first and second trays, respectively. In some embodiments, the power conductor terminal is a terminal of a circuit that is configured to supply power exceeding 150 Watts. Enclosures including multiple protective lids over power conductor terminal blocks are also provided.

Abstract: A floor nozzle apparatus is provided, including a receiving chamber having a receiving space, at least one cleaning roller arranged in the receiving space and rotatable about an axis of rotation, and a suction connector on which a suction stream acts during operation, wherein there is arranged between the receiving space and the suction connector a funnel-shaped duct device opening into the receiving space by an orifice and connecting to the suction connector or including the suction connector, and wherein the orifice has a width, in a direction of width parallel to the axis of rotation, having at least one of the following: (i) the width of the orifice is at least 30% of a width of the receiving space in the direction of width; (ii) the width of the orifice is at least three times a width of an opening in the suction connector in the direction of width.

Abstract: A speaker control system, including a speaker matrix, including a de-multiplexer including one or more audio control relays, a control unit operatively arranged to set the state of the one or more audio control relays, and determine the state of the one or more audio control relays, and a communication module.

Abstract: Described herein is a system for enabling a user to perform complex goals using multiple skills/applications of an intelligent assistant device. Skills may register as consumers of an action or providers of an action, and the consumer skills may be configured to invoke provider skills to perform actions. The system receives a request to perform an action from a skill along with some action data. The system validates the action data, selects another skill to perform the action, and forwards the request to the selected skill to perform the action.

Abstract: A power and data connectivity micro grid includes a first power sourcing equipment device having first and second power ports and first and second data ports, and configured to deliver DC power signals to the first and second power ports. The micro grid further includes first and second remote distribution nodes, and first and second splice enclosures, each splice enclosure having a power input port, a data input port, a power tap port, a data tap port, a power output port and a data output port. A first composite power-data cable is coupled between the first power port and the first data port of the first power sourcing equipment device and the power input port and the data input port of the first splice enclosure. A second composite power-data cable is coupled between the second power port and the second data port of the first power sourcing equipment device and the power input port and the data input port of the second splice enclosure.

Abstract: A renewable paraffinic composition is disclosed that contains at least 80 wt-% paraffins in a C16-C19 range for direct single phase immersion cooling. A direct single phase immersion cooling system and a method for direct single phase immersion cooling are also disclosed.

Abstract: A network asset location system and methods of its use and operation are disclosed. In one aspect, the network asset location system includes a mobile application component executable on a mobile device including a camera and a display, the mobile application component configured to receive image data from the camera and display an image on the display based on the image data and overlay information identifying one or more network assets identifiable in the image data. The network asset location system also includes an asset management tracking engine configured to receive the image data and generate the overlay information including an identification of a location of at least one of the one or more network assets within the image.