Abstract: A quetiapine fumarate composition for oral administration is provided comprising a pharmaceutically acceptable salt or solvate of quetiapine existing as a suspension in an aqueous carrier agent. The inventive liquid formulation demonstrates high bioavailability consistent with approved dosage forms, low agglomeration, reduced content of excipients commonly used in solid oral dosage forms and extended shelf life stability. Also provided is a method of manufacturing a liquid quetiapine suspension composition for oral administration and methods of administering therapeutically effective dosages of an oral liquid quetiapine suspension composition to patients in need thereof.

Abstract: A device for implanting at least one object beneath the skin of a patient includes a handle for grasping the device during insertion of an object. The handle may have a distal end, a proximal end, and an angled track formed on the handle. The angled track may have a stop at the distal portion that permits securing of the actuator and locks the cannula in a loaded position. A base may be connected to the handle. The base may include a post longitudinally fixed to the handle. The post may extend from the distal end of the handle. A hollow cannula may be positioned coaxially around and longitudinally slidable over the post from an extended position, in which at least one object is retained in the cannula, to a retracted position, in which at least one object is released from the cannula. A flexible actuator may be slidably engaged to the cannula to move the cannula from the extended position the retracted position to release the object from the cannula.

Abstract: A device for inserting implantable objects beneath the skin of a patient includes a handle for grasping the device and a base connected to the handle. The base comprises a post, a cannula, and a flexible actuator positioned in an angled track. The cannula is positioned coaxially around and is longitudinally slidable over the post from an extended position, where an implantable object is retained in the cannula, to a retracted position, where the implantable object is released from the cannula. A flexible actuator positioned on an angled track in the base is slidably engaged with a boss on the cannula and is used to move the cannula from an extended position to a retracted position to release the implantable object from the cannula; the actuator flexes between a locked and an unlocked position. The angled track provides for control of the release of the implantable object.

Abstract: A fluid collection and testing device includes a collection vial having a bottom and an open top along with an expresser sized for insertion into the vial open end. The expresser includes a ribbed base enabling fluid to pass therethrough and a support member holds the expresser within the collection vial with the ribbed base in a spaced apart relationship with the vial bottom. A fluid collector includes an absorbent member capturing a fluid and the absorbent member is sized for insertion into the expresser and is compressible against the ribbed base for releasing captured fluid through the ribbed base and into the vial bottom. A catch mechanism is provided for latching the fluid collector to the expresser after insertion into the expresser for enabling simultaneous removal of the expresser and the fluid collector from the collection vial.

Abstract: The present invention is directed to a method for the treatment of gastroparesis by the use of metoclopramide nasal formulation.

Abstract: The present invention is directed to a method for the treatment of gastroparesis by the use of metoclopramide nasal formulation.

Abstract: The present invention is directed to a method for the treatment of gastroparesis by the use of metoclopramide nasal formulation.