Patents by Inventor David Tristram Brown

David Tristram Brown has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL POTASSIUM CHANNEL INHIBITORS
    Publication number: 20240034717
    Abstract: The present invention relates to novel compounds, pharmaceutical compositions comprising such compounds and their use for treating, alleviating or preventing diseases or disorders relating to the activity of potassium channels.
    Type: Application
    Filed: September 21, 2021
    Publication date: February 1, 2024
    Inventors: David Tristram BROWN, Palle CHRISTOPHERSEN, Thomas Amos JACOBSEN, Janus S. LARSEN, Pernille Hartveit POULSEN, Dorte STRØBAEK
  • NOVEL POTASSIUM CHANNEL INHIBITORS
    Publication number: 20220169602
    Abstract: The present invention relates to novel compounds, pharmaceutical compositions comprising such compounds and their use for treating, alleviating or preventing diseases or disorders relating to the activity of potassium channels.
    Type: Application
    Filed: March 20, 2020
    Publication date: June 2, 2022
    Inventors: David Tristram BROWN, Palle CHRISTOPHERSEN, Thomas Amos JACOBSEN, Janus S. LARSEN, Pernille Hartveit Poulsen, Dorte STRØBAEK
  • Imidazole derivatives for the treatment of anxiety and related diseases
    Patent number: 8030339
    Abstract: This invention relates to novel imidazole derivatives, pharmaceutical compositions containing these compounds, and methods of treatment therewith. The compounds of the invention are useful in the treatment of central nervous system diseases and disorders, which are responsive to modulation of the GABAA receptor complex, and in particular for combating anxiety and related diseases.
    Type: Grant
    Filed: October 12, 2006
    Date of Patent: October 4, 2011
    Assignee: Neurosearch A/S
    Inventors: William Dalby Brown, Janus S. Larsen, Lene Teuber, David Tristram Brown, Philip K. Ahring, Naheed Mirza, Elsebet Østergaard Nielsen
  • Imidazole derivatives and their use for modulating the GABAreceptor complex
    Patent number: 7939556
    Abstract: This invention relates to novel imidazole derivatives, pharmaceutical compositions containing these compounds, and methods of treatment therewith. The compounds of the invention are useful in the treatment of central nervous system diseases and disorders, which are responsive to modulation of the GABAA receptor complex, and in particular for combating anxiety and related diseases.
    Type: Grant
    Filed: October 12, 2006
    Date of Patent: May 10, 2011
    Assignee: Neurosearch A/S
    Inventors: William Dalby Brown, Janus S. Larsen, Lene Teuber, David Tristram Brown, Philip K. Ahring, Naheed Mirza, Elsebet Østergaard Nielsen
  • Imidazole derivatives and their use for modulating the GABAreceptor complex
    Patent number: 7858649
    Abstract: This invention relates to novel imidazole derivatives, pharmaceutical compositions containing these compounds, and methods of treatment therewith. The compounds of the invention are of the general formula (I) and include any of its stereoisomers, any mixture of its stereoisomers, and pharmaceutically acceptable salts thereof. The compounds of the invention are useful in the treatment of central nervous system diseases and disorders, which are responsive to modulation of the GABAA receptor complex, and in particular for combating anxiety and related diseases.
    Type: Grant
    Filed: October 12, 2006
    Date of Patent: December 28, 2010
    Assignee: Neurosearch A/S
    Inventors: William Dalby Brown, Janus S. Larsen, Lene Teuber, David Tristram Brown, Philip K. Ahring, Naheed Mirza, Elsebet Østergaard Nielsen
  • Enantiomers of 3-heteroaryl-8H-8-azabicyclo(3.2.1)oct-2-ene and their use as monoamine neurotransmitter re-uptake inhibitors
    Patent number: 7781456
    Abstract: This invention relates to novel enantiomers useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Grant
    Filed: December 15, 2005
    Date of Patent: August 24, 2010
    Assignee: Neurosearch A/S
    Inventors: Dan Peters, David Tristram Brown, Börje Egestad, Sinikka Marjatta Taurio, legal representative, Eva Dam, David Spencer Jones, Brian Frøstrup, Elsebet Østergaard Nielsen, Gunnar M. Olsen, John Paul Redrobe
  • 3-aryloxy-8-aza-bicyclo[3.2.1]oct-6-ene derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
    Patent number: 7638532
    Abstract: This invention relates to novel 8-aza-bicyclo[3.2.1]oct-6-ene derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Grant
    Filed: June 7, 2006
    Date of Patent: December 29, 2009
    Assignee: NeuroSearch A/S
    Inventors: Dan Peters, David Tristram Brown, John Paul Redrobe, Elsebet Østergaard Nielsen
  • Imidazole Derivatives for the Treatment of Anxiety and Related Diseases
    Publication number: 20090233929
    Abstract: This invention relates to novel imidazole derivatives, pharmaceutical compositions containing these compounds, and methods of treatment therewith. The compounds of the invention are useful in the treatment of central nervous system diseases and disorders, which are responsive to modulation of the GABAA receptor complex, and in particular for combating anxiety and related diseases.
    Type: Application
    Filed: October 12, 2006
    Publication date: September 17, 2009
    Applicant: NeuroSearch A/S
    Inventors: William Dalby Brown, Janus S. Larsen, Lene Teuber, David Tristram Brown, Philip K. Ahring, Naheed Mirza, Elsebet Ostergaard Nielsen
  • IMIDAZOLE DERIVATIVES AND THEIR USE FOR MODULATING THE GABA ALPHA RECEPTOR COMPLEX
    Publication number: 20090209597
    Abstract: This invention relates to novel imidazole derivatives, pharmaceutical compositions containing these compounds, and methods of treatment therewith. The compounds of the invention are useful in the treatment of central nervous system diseases and disorders, which are responsive to modulation of the GABAA receptor complex, and in particular for combating anxiety and related diseases.
    Type: Application
    Filed: October 12, 2006
    Publication date: August 20, 2009
    Applicant: NeuroSearch A/S
    Inventors: William Dalby Brown, Janus S. Larsen, Lene Teuber, David Tristram Brown, Philip K. Ahring, Naheed Mirza, Elsebet Ostergaard Nielsen
  • Imidazole Derivatives and their use for Modulating the Gabaa Receptor Complex
    Publication number: 20090163566
    Abstract: This invention relates to novel imidazole derivatives of the general formula (I): pharmaceutical compositions containing these compounds, and methods of treatment therewith. The compounds of the invention are useful in the treatment of central nervous system diseases and disorders, which are responsive to modulation of the GABAA receptor complex, and in particular for combating anxiety and related diseases.
    Type: Application
    Filed: October 12, 2006
    Publication date: June 25, 2009
    Applicant: NeuroSearch A/S
    Inventors: William Dalby Brown, Janus S. Larsen, Lene Teuber, David Tristram Brown, Philip K. Ahring, Naheed Mirza, Elseber Østergaard Nielsen
  • 3-Aryloxy-8-aza-bicyclo[3.2.1]]oct-6-ene derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
    Publication number: 20090030035
    Abstract: This invention relates to novel 8-aza-bicyclo[3.2.1]oct-6-ene derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: June 7, 2006
    Publication date: January 29, 2009
    Applicant: NeuroSearch A/S
    Inventors: Dan Peters, David Tristram Brown, John Paul Redrobe, Elsebet Ostergaard Nielsen
  • Imidazole Derivatives and Their Use for Modulating the Gabaa Receptor Complex
    Publication number: 20080312303
    Abstract: This invention relates to novel imidazole derivatives, pharmaceutical compositions containing these compounds, and methods of treatment therewith. The compounds of the invention are useful in the treatment of central nervous system diseases and disorders, which are responsive to modulation of the GABAA receptor complex, and in particular for combating anxiety and related diseases.
    Type: Application
    Filed: October 12, 2006
    Publication date: December 18, 2008
    Applicant: NeuroSearch A/S
    Inventors: William Dalby Brown, Janus S. Larsen, Lene Teuber, David Tristram Brown, Philip K. Ahring, Naheed Mirza, Elsebet Ostergaard Nielsen
  • Enantiomers of 3-Heteroaryl-8H-8-Azabicyclo (3.2.1) Oct-2-Ene and their Use as Monoamine Neurotransmitter Re-Uptake Inhibitors
    Publication number: 20080214820
    Abstract: This invention relates to novel enantiomers useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: December 15, 2005
    Publication date: September 4, 2008
    Applicant: NeuroSearch A/S
    Inventors: Dan Peters, David Tristram Brown, Borje Egestad, Eva Dam, David Spencer Jones, Brian Frostrup, Elsebet Ostergaard Nielsen, Gunnar M. Olsen, John Paul Redrobe