Abstract: The present disclosure relates methods for treating skin disorders caused by an immune deficiency with topical formulations comprising ethyl (R)-4-((1-(2-cyanoacetyl)piperidin-3-yl)amino)-1H-pyrrolo[2,3-b]pyridine-5-carboxylate (Compound I) or pharmaceutically acceptable derivative thereof. In particular, the topical formulations described herein may be used to treat atopic dermatitis, alopecia areata, or vitiligo.

Abstract: Aspects of the disclosure relate to phosphotriesterase (PTE) enzymes and PTE-related (PTER) enzymes and their use in hydrolyzing OPNAs.

Abstract: A parts packing method is used to optimize build bed part placement for additive manufacturing. The method includes a user interface to parts packing software, enabling a process engineer to select parts from a pool of parts, group parts to have uniform orientation, and specify a range of angles and rotation of the parts. Additionally, the user interface accepts input related to process variations among different printers as well as drift over time of a single printer. The user interface feeds the data into the parts packing program to optimize build bed part placement.

Abstract: A medical instrument port is described for use with a surgical mask or other protective face covering. The medical instrument port provides a sealed pathway through which a medical instrument can be passed without exposing the clinician to aerosolized droplets expelled from the patient's respiratory system when the medical instrument is introduced into the patient's nasal and/or oral passages.

Abstract: Provided is a method for configuring at least one rule, e.g., using a graphical user interface. The method may include displaying a graphical user interface including a polygon having at least three edges and an icon at a first position within the polygon. Each edge of the polygon may be associated with a potential outcome of at least one rule. An input to move the icon to a second position within the polygon may be received. The graphical user interface may be displayed with the icon at the second position within the polygon. A distance from the second position of the icon to each edge of the polygon may be determined. The rule(s) may be adjusted based on the distance from the second position of the icon to each edge of the polygon. A system and computer program product are also disclosed.

Abstract: The invention relates to a method and system for Industry Gift Voucher (IGV) management in fence networks. The method includes determining a base value, a unique alphanumeric key, and an expiration date to create an IGV; assigning an ownership of the IGV to a first user upon receiving a purchase request from the first user and required information of the first user; transferring the ownership of the IGV to a second user upon receiving a gift request from the first user and required information of the second user; and facilitating redemption of the IGV to the second user to utilize the IGV through at least one enterprise of a plurality of enterprises associated with one of the fence networks, wherein the IGV is circulated within the fence networks.

Abstract: A system and method for assisting a driver in controlling a vehicle, the vehicle comprising one or more driver controls, the method comprising determining an optimal path for the vehicle; determining, based on the current motion of the vehicle and a current setting of one or more driver controls, a predicted path of the vehicle; determining if there is a difference between the optimal path for the vehicle and the predicted path of the vehicle; and if it is determined that there is a difference between the optimal path and the predicted path, delivering haptic and non-haptic feedback to the driver of the vehicle, the feedback comprising an indication that the driver should alter the current setting of one or more driver controls, wherein alteration of the setting of one or more driver controls modifies the motion of the vehicle to reduce the difference.

Abstract: Provided is a method for configuring at least one rule, e.g., using a graphical user interface. The method may include displaying a graphical user interface including a polygon having at least three edges and an icon at a first position within the polygon. Each edge of the polygon may be associated with a potential outcome of at least one rule. An input to move the icon to a second position within the polygon may be received. The graphical user interface may be displayed with the icon at the second position within the polygon. A distance from the second position of the icon to each edge of the polygon may be determined. The rule(s) may be adjusted based on the distance from the second position of the icon to each edge of the polygon. A system and computer program product are also disclosed.

Abstract: An augmented reality system for assisting the driver of a vehicle comprising a display headset, a positioning system and a display driver configured to generate graphic elements which appear to the driver to move independently with respect to one another.

Abstract: Provided is a method for configuring at least one rule, e.g., using a graphical user interface. The method may include displaying a graphical user interface including a polygon having at least three edges and an icon at a first position within the polygon. Each edge of the polygon may be associated with a potential outcome of at least one rule. An input to move the icon to a second position within the polygon may be received. The graphical user interface may be displayed with the icon at the second position within the polygon. A distance from the second position of the icon to each edge of the polygon may be determined. The rule(s) may be adjusted based on the distance from the second position of the icon to each edge of the polygon. A system and computer program product are also disclosed.

Abstract: A wettable barrier fabric is provided that exhibits barrier function to dry particles and splashed liquids while also exhibiting wettability and wicking properties. A garment formed from a wettable barrier fabric that has good absorption properties and that retains good barrier properties is also provided.

Abstract: An elastomeric composition, including at least one skin layer and a core layer, with non-blocking properties such that the elastomeric composition can be wound is provided. The core layer includes an elastomer, and the skin layer includes an elastomer, which may be the same or different from the core layer, and a non-elastic polyolefin. Further, the skin layer can be present as a small portion of the total elastomeric composition, and may maintain the elastic efficiency of the composition.

Abstract: In various embodiments, the disclosed system facilitates the access, creation, addition, deletion, revision, security, availability, integrity, registration, conclusion, validation, and notification of certain digital assets, such as an individual's consent for use or reuse or personal information, legal documentation, on a distributed ledger or blockchain system by using cross-party authentication of both a creator's and validator's unique identifying information. In general, in multiple embodiments, the disclosed system provides the ability to update details to documentation in real time, improves security through private key encryption and the implementation of a distributed ledger, and makes the documentation an immutable record.

Abstract: Provided is a method for configuring at least one rule, e.g., using a graphical user interface. The method may include displaying a graphical user interface including a polygon having at least three edges and an icon at a first position within the polygon. Each edge of the polygon may be associated with a potential outcome of at least one rule. An input to move the icon to a second position within the polygon may be received. The graphical user interface may be displayed with the icon at the second position within the polygon. A distance from the second position of the icon to each edge of the polygon may be determined. The rule(s) may be adjusted based on the distance from the second position of the icon to each edge of the polygon. A system and computer program product are also disclosed.

Abstract: Provided is a method for configuring at least one rule, e.g., using a graphical user interface. The method may include displaying a graphical user interface including a polygon having at least three edges and an icon at a first position within the polygon. Each edge of the polygon may be associated with a potential outcome of at least one rule. An input to move the icon to a second position within the polygon may be received. The graphical user interface may be displayed with the icon at the second position within the polygon. A distance from the second position of the icon to each edge of the polygon may be determined. The rule(s) may be adjusted based on the distance from the second position of the icon to each edge of the polygon. A system and computer program product are also disclosed.

Abstract: The present disclosure is drawn to 3D printing kits and methods of making 3D printed articles. In one example, a 3D printing kit can include a powder bed material, a fusible fluid, and an activator fluid. The powder bed material can include polymer particles. The fusible fluid can include a radiation absorber. The fusible fluid can be to selectively apply to the powder bed material. The activator fluid can include a non-conductive electroless metal plating activator. The activator fluid can also be to selectively apply to the powder bed material.

Abstract: A system and method for assisting a driver in controlling a vehicle, the vehicle comprising one or more driver controls, the method comprising determining an optimal path for the vehicle; determining, based on the current motion of the vehicle and a current setting of one or more driver controls, a predicted path of the vehicle; determining if there is a difference between the optimal path for the vehicle and the predicted path of the vehicle; and if it is determined that there is a difference between the optimal path and the predicted path, delivering haptic and non-haptic feedback to the driver of the vehicle, the feedback comprising an indication that the driver should alter the current setting of one or more driver controls, wherein alteration of the setting of one or more driver controls modifies the motion of the vehicle to reduce the difference.

Abstract: An augmented reality system for assisting the driver of a vehicle comprising a display headset, a positioning system and a display driver configured to generate graphic elements which appear to the driver to move independently with respect to one another.

Abstract: The present disclosure is drawn to 3D printing kits and methods of making 3D printed articles. In one example, a 3D printing kit can include a powder bed material, a fusible fluid, and an activator fluid. The powder bed material can include polymer particles. The fusible fluid can include a radiation absorber. The fusible fluid can be to selectively apply to the powder bed material. The activator fluid can include a non-conductive electroless metal plating activator. The activator fluid can also be to selectively apply to the powder bed material.