Patents by Inventor David Tully

David Tully has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250007947
    Abstract: A system facilitating attack-resilient communications between devices. The system comprises a master system comprising a master network switch and master encryption retransmission devices. The master encryption retransmission devices comprises a master encryption unit and a master communication unit communicatively coupled with the master encryption unit. The master system is configurable for connecting with a slave system comprising a slave network switch and slave encryption retransmission devices connected with the slave network switch. Each of a managing master encryption retransmission device and a managing slave encryption retransmission device receives a managing packet.
    Type: Application
    Filed: June 30, 2023
    Publication date: January 2, 2025
    Inventors: Eric Adolphe, Benjamin David Tullis
  • Publication number: 20190376426
    Abstract: An after-treatment system includes a selective catalyst reduction on filter (SCRF) device in communication with exhaust gases from an engine yielding treated exhaust gases. A nitrogen oxides (NOx) sensor is configured to measure the treated exhaust gases and has an output signal that is NOx and ammonia (NH3) cross-sensitive. A NOx sensor model is coupled to receive the output signal and mass flow data for the treated exhaust gases and provides a NOx model signal to an electronic control unit (ECU) that is operatively associated with the after-treatment system and the engine. The NOx model signal represents an exhaust gas NOx concentration estimate based upon an actual NOx concentration and an actual NH3 concentration of the exhaust gas. The ECU is operable upon the NOx concentration estimate to control the after-treatment system and the engine to effect an overall reduction in actual NOx concentration of the treated exhaust gases.
    Type: Application
    Filed: June 8, 2018
    Publication date: December 12, 2019
    Applicant: GM GLOBAL TECHNOLOGY OPERATIONS LLC
    Inventors: Jaime Andres Cespedes Garcia, Giuseppe Mazzara Bologna, Maria Camuglia, Carlos Idefonso Hoyos Velasco, David Tulli
  • Publication number: 20190376427
    Abstract: An exhaust gas after-treatment system for an internal combustion engine that includes a selective catalyst reduction on filter (SCRF) exhaust gas after-treatment device in communication with exhaust gases from the internal combustion engine and having a treated exhaust gas output. An oxides of nitrogen (NOx) sensor is coupled to the treated exhaust gases and has a NOx sensor output signal that is NOx and ammonia (NH3) cross-sensitive. A closed loop observer (CLO) is operatively coupled to receive the NOx sensor output signal and provides a NOx concentration signal to an electronic control unit that is operatively associated with the exhaust gas after-treatment system and the internal combustion engine.
    Type: Application
    Filed: June 8, 2018
    Publication date: December 12, 2019
    Applicant: GM GLOBAL TECHNOLOGY OPERATIONS LLC
    Inventors: Giuseppe Mazzara Bologna, Maria Camuglia, Carlos Ildefonso Hoyos Velasco, Carmen Pedicini, David Tulli, Daniele Bernardini, Alberto Bemporad
  • Patent number: 10145284
    Abstract: An automotive vehicle includes an internal combustion engine and an exhaust system. The exhaust treatment system includes a dosing system that injects NH3 into an exhaust gas stream generated by the engine. An SCR device stores an amount of the NH3 and converts NOx into diatomic nitrogen (N2) and water (H2O) based on the stored amount of the NH3. The vehicle further includes an SCR status estimator device and a controller. The SCR status estimator device determines an NH3 coverage ratio (R), which indicates a stored amount of NH3 with respect to a maximum NH3 storage capacity of the SCR device. The controller determines a target NOx reduction efficiency (?NOx) of the SCR device, and an NH3 coverage ratio set point (Rsp) based on the ?NOx. The controller also generates an NH3 control signal (u) that controls the dosing system based on a comparison between the R and the Rsp.
    Type: Grant
    Filed: April 25, 2017
    Date of Patent: December 4, 2018
    Assignee: GM GLOBAL TECHNOLOGY OPERATIONS LLC
    Inventors: Carlos Ildefonso Hoyos Velasco, Vincenzo Alfieri, Maria Camuglia, Giuseppe Conte, Giuseppe Mazzara Bologna, Carmen Pedicini, David Tulli
  • Publication number: 20180306082
    Abstract: An automotive vehicle includes an internal combustion engine and an exhaust system. The exhaust treatment system includes a dosing system that injects NH3 into an exhaust gas stream generated by the engine. An SCR device stores an amount of the NH3 and converts NOx into diatomic nitrogen (N2) and water (H2O) based on the stored amount of the NH3. The vehicle further includes an SCR status estimator device and a controller. The SCR status estimator device determines an NH3 coverage ratio (R), which indicates a stored amount of NH3 with respect to a maximum NH3 storage capacity of the SCR device. The controller determines a target NOx reduction efficiency (?NOx) of the SCR device, and an NH3 coverage ratio set point (Rsp) based on the ?NOx. The controller also generates an NH3 control signal (u) that controls the dosing system based on a comparison between the R and the Rsp.
    Type: Application
    Filed: April 25, 2017
    Publication date: October 25, 2018
    Inventors: Carlos Ildefonso Hoyos Velasco, Vincenzo Alfieri, Maria Camuglia, Giuseppe Conte, Giuseppe Mazzara Bologna, Carmen Pedicini, David Tulli
  • Patent number: 8490888
    Abstract: A fuel injector for delivering fuel to a combustion chamber having a chamber ceiling, the fuel injector having a primary axis and able to control fuel delivery through a first outlet opening or together through both the first outlet opening and a second outlet opening. The first and second outlet openings are oriented such that, in use, when fuel delivery is permitted through only the first outlet opening, a first spray formation reaches a first target distance below the chamber ceiling at a radial distance from the primary axis. When fuel delivery is permitted through both openings together, respective first and second spray formations merge externally of the injector so as to give rise to a combined spray formation reaching second target distance below the chamber ceiling at the radial distance from the primary nozzle axis, wherein the second target distance is larger than the first target distance.
    Type: Grant
    Filed: March 30, 2009
    Date of Patent: July 23, 2013
    Assignee: Delphi Technologies Holding S.arl
    Inventors: Godfrey Greeves, Simon David Tullis
  • Publication number: 20110186648
    Abstract: A fuel injector mountable with respect to a combustion chamber for delivering fuel thereto, the combustion chamber comprising a chamber ceiling and a chamber wall, the fuel injector comprising a nozzle body having a primary nozzle axis; a first outlet opening having a first axis; a second outlet opening having a second axis; and means for controlling fuel delivery through the first and second outlet openings. The means for controlling fuel delivery comprises an inner valve needle and an outer valve needle, and is arranged to permit fuel delivery from only the first outlet opening, or through both the first and second outlet openings together. The first and second outlet openings are oriented such that, in use, when fuel delivery is permitted through only said first outlet opening, a first spray formation is injected along the first axis, the first spray formation reaching a first target distance below said chamber ceiling at a radial distance from the primary nozzle axis.
    Type: Application
    Filed: March 30, 2009
    Publication date: August 4, 2011
    Applicant: DELPHI TECHNOLOGIES HOLDING, S.ARL
    Inventors: Godfrey Greeves, Simon David Tullis
  • Publication number: 20080242671
    Abstract: The present invention provides compounds, compositions and methods for the selective inhibition of cathepsin S. In a preferred aspect, cathepsin S is selectively inhibited in the presence of at least one other cathepsin isozyme. The present invention also provides methods for treating a disease state in a subject by selectively inhibiting cathepsin S.
    Type: Application
    Filed: March 25, 2008
    Publication date: October 2, 2008
    Applicant: IRM LLC
    Inventors: Hong Liu, Phillip Alper, Arnab Chatterjee, David Tully, Badry Bursulaya, David Woodmansee, Robert Epple, Jennifer Leslie Harris, Jun Li
  • Patent number: 7384970
    Abstract: The present invention provides compounds, compositions and methods for the selective inhibition of cathepsin S. In a preferred aspect, cathepsin S is selectively inhibited in the presence of at least one other cathepsin isozyme. The present invention also provides methods for treating a disease state in a subject by selectively inhibiting cathepsin S.
    Type: Grant
    Filed: March 23, 2004
    Date of Patent: June 10, 2008
    Assignee: IRM LLC
    Inventors: Hong Liu, Phil Alper, Arnab Chatterjee, David Tully, Badry Bursulaya, David Woodmansee, Robert Epple, Jennifer Leslie Harris, Jun Li
  • Publication number: 20080108595
    Abstract: The present invention provides compounds, compositions and methods for the selective inhibition of cathepsin S. In a preferred aspect, cathepsin S is selectively inhibited in the presence of at least one other cathepsin isozyme. The present invention also provides methods for treating a disease state in a subject by selectively inhibiting cathepsin S.
    Type: Application
    Filed: October 31, 2007
    Publication date: May 8, 2008
    Applicant: IRM LLC
    Inventors: Hong Liu, Arnab Chatterjee, David Tully, Phillip Alper, Badry Bursulaya, Jianhua Guo, David Woodmansee, Daniel Mutnick, Donald Karanewsky, Yun He
  • Patent number: 7307095
    Abstract: The present invention provides compounds, compositions and methods for the selective inhibition of cathepsin S. In a preferred aspect, cathepsin S is selectively inhibited in the presence of at least one other cathepsin isozyme. The present invention also provides methods for treating a disease state in a subject by selectively inhibiting cathepsin S.
    Type: Grant
    Filed: January 5, 2007
    Date of Patent: December 11, 2007
    Assignee: IRM LLC
    Inventors: Hong Liu, David Tully, Phillip Alper, Robert Epple, Arnab Chatterjee, Michael Roberts
  • Publication number: 20070275906
    Abstract: The invention provides compounds and pharmaceutical compositions thereof, which are useful for modulating channel activating proteases, and methods for, using such compounds to treat, ameliorate or prevent a condition associated with a channel activating protease, including but not limited to prostasin, PRSS22, TMPRSS11 (e.g., TMPRSS11B, TMPRSS11E), TMPRSS2, TMPRSS3, TMPRSS4 (MTSP-2), matriptase (MTSP-1), CAP2, CAP3, trypsin, cathepsin A, or neutrophil elastase.
    Type: Application
    Filed: May 16, 2007
    Publication date: November 29, 2007
    Applicant: IRM LLC
    Inventors: David Tully, Arnab Chatterjee, Agnes Vidal, Hank Petrassi, Zhiwei Wang, Badry Bursulaya, Glen Spraggon
  • Publication number: 20070276002
    Abstract: The invention provides compounds and pharmaceutical compositions thereof, which are useful for modulating channel activating proteases, and methods for using such compounds to treat, ameliorate or prevent a condition associated with a channel activating protease, including but not limited to prostasin, PRSS22, TMPRSS11 (e.g., TMPRSS11B, TMPRSS11E), TMPRSS2, TMPRSS3, TMPRSS4 (MTSP-2), matriptase (MTSP-1), CAP2, CAP3, trypsin, cathepsin A, or neutrophil elastase.
    Type: Application
    Filed: May 15, 2007
    Publication date: November 29, 2007
    Applicant: IRM LLC
    Inventors: David Tully, Arnab Chatterjee, Hank Michael Petrassi, Badry Bursulaya, Glen Spraggon
  • Publication number: 20070232606
    Abstract: The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of Cathepsin S.
    Type: Application
    Filed: April 29, 2005
    Publication date: October 4, 2007
    Inventors: Hong Liu, David Tully, Arnab Chatterjee, Phillip Alper, David Woodmansee, Daniel Mutnick
  • Publication number: 20070123523
    Abstract: The present invention provides compounds, compositions and methods for the selective inhibition of cathepsin S. In a preferred aspect, cathepsin S is selectively inhibited in the presence of at least one other cathepsin isozyme. The present invention also provides methods for treating a disease state in a subject by selectively inhibiting cathepsin S.
    Type: Application
    Filed: January 5, 2007
    Publication date: May 31, 2007
    Applicant: IRM LLC
    Inventors: Hong Liu, David Tully, Phillip Alper, Robert Epple, Arnab Chatterjee, Michael Roberts
  • Patent number: 7173051
    Abstract: The present invention provides compounds, compositions and methods for the selective inhibition of cathepsin S. In a preferred aspect, cathepsin S is selectively inhibited in the presence of at least one other cathepsin isozyme. The present invention also provides methods for treating a disease state in a subject by selectively inhibiting cathepsin S.
    Type: Grant
    Filed: June 10, 2004
    Date of Patent: February 6, 2007
    Assignee: IRM, LLC
    Inventors: Hong Liu, David Tully, Phillip Alper, Robert Epple, Arnab Chatterjee, Michael Roberts
  • Patent number: 7109243
    Abstract: The present invention provides compounds, compositions and methods for the selective inhibition of cathepsin S. In a preferred aspect, cathepsin S is selectively inhibited in the presence of at least one other cathepsin isozyme (e.g., cathespin K). The present invention also provides methods for treating a disease state in a subject by selectively inhibiting cathepsin S.
    Type: Grant
    Filed: March 23, 2004
    Date of Patent: September 19, 2006
    Assignee: IRM LLC
    Inventors: Hong Liu, David Tully, Robert Epple, Badry Bursulaya, Jennifer Williams, Arnab Chatterjee, Jennifer Leslie Harris, Jun Li
  • Patent number: 6906158
    Abstract: This invention provides novel methods for synthesis of narrow polydispersity oxazolone-containing polymers via nitroxide-mediated living free radical polymerization, as well as the products and derivatives thereof.
    Type: Grant
    Filed: March 11, 2004
    Date of Patent: June 14, 2005
    Assignee: IRM, LLC
    Inventor: David Tully
  • Publication number: 20050113356
    Abstract: The present invention provides compounds, compositions and methods for the selective inhibition of cathepsin S. In a preferred aspect, cathepsin S is selectively inhibited in the presence of at least one other cathepsin isozyme. The present invention also provides methods for treating a disease state in a subject by selectively inhibiting cathepsin S.
    Type: Application
    Filed: August 18, 2004
    Publication date: May 26, 2005
    Applicant: IRM LLC
    Inventors: Hong Liu, Arnab Chatterjee, David Tully, Phillip Alper, Badry Bursulaya, Jianhua Guo, David Woodmansee, Daniel Mutnick, Donald Karanewsky, Yun He
  • Publication number: 20050049244
    Abstract: The present invention provides compounds, compositions and methods for the selective inhibition of cathepsin S. In a preferred aspect, cathepsin S is selectively inhibited in the presence of at least one other cathepsin isozyme. The present invention also provides methods for treating a disease state in a subject by selectively inhibiting cathepsin S.
    Type: Application
    Filed: June 10, 2004
    Publication date: March 3, 2005
    Applicant: IRM LLC
    Inventors: Hong Liu, David Tully, Phillip Alper, Robert Epple, Arnab Chatterjee, Michael Roberts