Patents by Inventor David Tuschel
David Tuschel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7414725Abstract: The disclosure generally relates to a multimode imaging apparatus for simultaneously obtaining multiple wavelength-discriminative spectral images of a sample.Type: GrantFiled: September 26, 2007Date of Patent: August 19, 2008Assignee: ChemImage CorporationInventors: Xinghua Wang, Thomas Voigt, David Tuschel, Chenhui Wang, Patrick Treado
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Patent number: 7411672Abstract: The disclosure generally relates to a system for detecting a change in an attribute of a substance. The system may include a photon source for producing a first of a plurality of photons which interact with the substance while an attribute of the substance changes to produce a second plurality of photons. The system may also include a filter for receiving the collected photons and providing filtered photons; a photon detector for receiving the filtered photons and obtaining therefrom a spectrum of the substance; and a processor for detecting an aspect of the filtered photons wherein the aspect of the filtered photons is the function of the attribute of the substance.Type: GrantFiled: July 3, 2007Date of Patent: August 12, 2008Assignee: ChemImage CorporationInventors: David Tuschel, Thomas Voigt
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Patent number: 7408636Abstract: The disclosure is generally directed to a method and apparatus for providing an image of a sample. The apparatus includes an illuminating source for transmitting photons to a sample. The transmitted photons illuminate the sample or are scattered upon reaching the sample. A lens collects the scattered photons and transmits the scattered photons to a tunable filter for forming an image. The illuminating photons traveling from the illuminating source to the sample do not pass through the lens.Type: GrantFiled: June 30, 2004Date of Patent: August 5, 2008Assignee: ChemImage CorporationInventors: David Tuschel, Wesley H. Hutchison, Myles P. Berkman
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Patent number: 7394542Abstract: The disclosure generally relates to a system for detecting a change in an attribute of a substance. The system may include a photon source for producing a first of a plurality of photons which interact with the substance while an attribute of the substance changes to produce a second plurality of photons. The system may also include a filter for receiving the collected photons and providing filtered photons; a photon detector for receiving the filtered photons and obtaining therefrom a spectrum of the substance; and a processor for detecting an aspect of the filtered photons wherein the aspect of the filtered photons is the function of the attribute of the substance.Type: GrantFiled: August 18, 2004Date of Patent: July 1, 2008Assignee: ChemImage CorporationInventors: Thomas Voigt, David Tuschel
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Publication number: 20080093539Abstract: In one embodiment, the disclosure relates to a method for determining illumination parameters for a stained sample, the method may include providing a stained sample and obtaining an absorption band of the sample; obtaining an emission band of the sample and determining the illumination parameters for the sample as a function of the absorption band and the emission band of the sample.Type: ApplicationFiled: October 15, 2007Publication date: April 24, 2008Applicant: CHEMIMAGE CORPORATIONInventors: David Tuschel, John Maier
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Publication number: 20080094614Abstract: A pulse photobleaching methodology wherein a monochromatic illumination (e.g., laser illumination) having a higher power intensity (photobleaching power) just below the photodamage threshold of a luminescent sample is initially used to significantly attenuate sample luminescence without photothermally destroying the sample material. Thereafter, the laser power density may be reduced to a significantly lower level (analytical power level) to carry out spectroscopic measurements (e.g., collection of Raman scattered photons) on the sample. In one embodiment, the laser illumination wavelength remains the same despite changes in laser power intensity. Some figures-of-merit may be computed from optical measurements made at the analytical power level to guide the photobleaching process. Sample-dependent combinations of laser power density and short exposure times may be obtained to significantly expedite photobleaching to assist in collection of sample spectral data in the field without a long wait.Type: ApplicationFiled: October 19, 2007Publication date: April 24, 2008Applicant: Chemlmage CorporationInventors: David Tuschel, Arjun Bangalore
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Publication number: 20080088844Abstract: The disclosure generally relates to a multimode imaging apparatus for simultaneously obtaining multiple wavelength-discriminative spectral images of a sample.Type: ApplicationFiled: September 26, 2007Publication date: April 17, 2008Applicant: CHEMIMAGE CORPORATIONInventors: Xinghua Wang, Thomas Voigt, David Tuschel, Chenhui Wang, Patrick Treado
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Patent number: 7342214Abstract: In one embodiment, the disclosure relates to a method for determining illumination parameters for a stained sample, the method may include providing a stained sample and obtaining an absorption band of the sample; obtaining an emission band of the sample and determining the illumination parameters for the sample as a function of the absorption band and the emission band of the sample.Type: GrantFiled: May 15, 2006Date of Patent: March 11, 2008Assignee: Chemimage CorporationInventors: David Tuschel, John S. Maier
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Patent number: 7317526Abstract: A system and method for detecting dynamic changes that occur in a sample between a first time interval and a second time interval using a series of at least first and second sequential chemical images of the sample. During the first time interval: (i) the sample is illuminated with a plurality of photons to thereby produce photons scattered or emitted by the sample; (ii) a two-dimensional array of detection elements is used to simultaneously detect scattered or emitted photons in a first predetermined wavelength band from different locations on or within the sample; and (iii) the two-dimensional array of detection elements is thereafter used one or more further times to simultaneously detect scattered or emitted photons in one or more further predetermined wavelength band(s) from different locations on or within the sample. The outputs of the two-dimensional array of detection elements during the first time interval are then combined to generate the first chemical image of the sample.Type: GrantFiled: April 6, 2006Date of Patent: January 8, 2008Assignee: Chem Image CorporationInventors: Thomas C. Voigt, David Tuschel, John S. Maier
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Publication number: 20070258089Abstract: The disclosure generally relates to a system for detecting a change in an attribute of a substance. The system may include a photon source for producing a first of a plurality of photons which interact with the substance while an attribute of the substance changes to produce a second plurality of photons. The system may also include a filter for receiving the collected photons and providing filtered photons; a photon detector for receiving the filtered photons and obtaining therefrom a spectrum of the substance; and a processor for detecting an aspect of the filtered photons wherein the aspect of the filtered photons is the function of the attribute of the substance.Type: ApplicationFiled: July 3, 2007Publication date: November 8, 2007Applicant: Chem Image CorporationInventors: David Tuschel, Thomas Voigt
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Publication number: 20070241177Abstract: The disclosure relates generally to methods and apparatus for protecting against counterfeit products and for methods and apparatus for providing counterfeiting protection for an object. In one embodiment, the method includes the steps of: (a) accessing an object including an identifying mark having a first portion and a second portion wherein said second portion includes an encrypted feature; (b) reading the first portion to thereby obtain a first set of information; (c) transmitting the first set of information to a remote location; (d) receiving from the remote location a second set of information; and (e) reading the second portion using the second set of information to thereby determine the authenticity of the object.Type: ApplicationFiled: December 20, 2006Publication date: October 18, 2007Inventors: David Tuschel, Wesley Hutchison, Thomas Voigt
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Patent number: 7283241Abstract: The disclosure generally relates to a multimode imaging apparatus for simultaneously obtaining multiple wavelength-discriminative spectral images of a sample.Type: GrantFiled: January 31, 2005Date of Patent: October 16, 2007Assignee: Chemimage Corp.Inventors: Xinghua Wang, Thomas C. Voigt, David Tuschel, Chenhui Wang, Patrick J. Treado
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Publication number: 20070221732Abstract: The disclosure relates generally to methods and apparatus for protecting against counterfeit products and for methods and apparatus for providing counterfeiting protection for an object. In one embodiment, the method includes the steps of: (a) accessing an object including an identifying mark having a first portion and a second portion wherein said second portion includes an encrypted feature; (b) reading the first portion to thereby obtain a first set of information; (c) transmitting the first set of information to a remote location; (d) receiving from the remote location a second set of information; and (e) reading the second portion using the second set of information to thereby determine the authenticity of the object.Type: ApplicationFiled: December 20, 2006Publication date: September 27, 2007Inventors: David Tuschel, Wesley Hutchison, Thomas Voigt
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Publication number: 20070222982Abstract: A system and method for collecting Raman data sets without the “contaminating” effect of luminescence emitted photons. Using a frame transfer CCD for time resolved data collection, Raman imaging may be performed without photobleaching the sample. The system may include a light source, a frame transfer CCD, an optical lens and at least one controller. The light source illuminates the sample with a plurality of photons to generate scattered photons from the sample. The frame transfer CCD has an image array and a storage array. The optical lens collects scattered photons and directs the scattered photons to the image array. The controller transfers a Raman data set representative of the scattered photons from the image array to the storage array. The frame transfer CCD may be configured so as the image array integrates the scattered photons during a Raman integration time and the controller transfers the Raman data set from the image array to storage array during a parallel transfer time.Type: ApplicationFiled: March 26, 2007Publication date: September 27, 2007Inventors: David Tuschel, Jingyun Zhang
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Patent number: 7268330Abstract: In one embodiment, the disclosure relates to a method for determining illumination parameters for a sample, the method may include obtaining an absorption band of the sample; obtaining an emission band of the sample and determining the illumination parameters for the sample as a function of the absorption band and the emission band of the sample.Type: GrantFiled: June 13, 2006Date of Patent: September 11, 2007Assignee: Chemimage CorporationInventors: David Tuschel, Thomas Voigt, Chenhui Wang
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Publication number: 20070206185Abstract: The present disclosure describes methods and systems that combine Raman spectroscopy performed in a manner that utilizes one or more of widefield illumination, simultaneous multipoint Raman spectral acquisition, and spectral unmixing for the purpose of high throughput polymorph screening. Features of this methodology include: (a) high throughput polymorph screening to reduce crystal orientation effects on Raman spectra; (b) in-well multi-polymorph screening using increased statistical sampling; and (c) multipoint spectral sampling to enable spectral unmixing.Type: ApplicationFiled: March 5, 2007Publication date: September 6, 2007Applicant: CHEMIMAGE CORPORATIONInventors: David Tuschel, Patrick J. Treado, Matthew P. Nelson
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Publication number: 20070200335Abstract: The disclosure relates generally to methods and apparatus for protecting against counterfeit products and for methods and apparatus for providing counterfeiting protection for an object. In one embodiment, the method includes the steps of: (a) accessing an object including an identifying mark having a first portion and a second portion wherein said second portion includes an encrypted feature; (b) reading the first portion to thereby obtain a first set of information; (c) transmitting the first set of information to a remote location; (d) receiving from the remote location a second set of information; and (e) reading the second portion using the second set of information to thereby determine the authenticity of the object.Type: ApplicationFiled: December 20, 2006Publication date: August 30, 2007Inventors: David Tuschel, Wesley Hutchison
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Publication number: 20070182959Abstract: The invention relates to methods of dynamic chemical imaging, including methods of cellular imaging. The method comprises illuminating at least a portion of a cell with substantially monochromatic light and assessing Raman-shifted light scattered from the illuminated portion at a plurality of discrete times. The Raman-shifted light can be assessed at a plurality of Raman shift (RS) values at each of the discrete times, and the RS values can be selected to be characteristic of a pre-selected component at each of the discrete times. Multivariate analysis of Raman spectral features of the images thus obtained can yield the location and chemical identity of components in the field of view. This information can be combined or overlaid with other spectral data (e.g., a visible microscopic image) obtained from the field of view.Type: ApplicationFiled: June 30, 2005Publication date: August 9, 2007Applicant: ChemImage, Inc.Inventors: John Maier, Patrick Treado, David Tuschel, Thomas Voigt
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Publication number: 20070152032Abstract: The disclosure relates generally to methods and apparatus for protecting against counterfeit products and for methods and apparatus for providing counterfeiting protection for an object. In one embodiment, the method includes the steps of: (a) accessing an object including an identifying mark having a first portion and a second portion wherein said second portion includes an encrypted feature; (b) reading the first portion to thereby obtain a first set of information; (c) transmitting the first set of information to a remote location; (d) receiving from the remote location a second set of information; and (e) reading the second portion using the second set of information to thereby determine the authenticity of the object.Type: ApplicationFiled: December 20, 2006Publication date: July 5, 2007Inventors: David Tuschel, Thomas C. Voigt
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Publication number: 20070152056Abstract: The disclosure relates generally to methods and apparatus for protecting against counterfeit products and for methods and apparatus for providing counterfeiting protection for an object. In one embodiment, the method includes the steps of: (a) accessing an object including an identifying mark having a first portion and a second portion wherein said second portion includes an encrypted feature; (b) reading the first portion to thereby obtain a first set of information; (c) transmitting the first set of information to a remote location; (d) receiving from the remote location a second set of information; and (e) reading the second portion using the second set of information to thereby determine the authenticity of the object.Type: ApplicationFiled: December 20, 2006Publication date: July 5, 2007Inventors: David Tuschel, Wesley Hutchison, Thomas Voigt