Patents by Inventor David Tuveson

David Tuveson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HEDGEHOG PATHWAY INHIBITORS
    Publication number: 20120020876
    Abstract: This disclosure generally relates to methods useful for improving, for example, blood vessel density and/or blood vessel patency to a tissue by administration of a hedgehog pathway inhibitor. In certain embodiments, the hedgehog pathway inhibitor is administered with an agent to improve the delivery of the agent to the tissue. In certain embodiments, the tissue comprises tumor tissue.
    Type: Application
    Filed: January 22, 2010
    Publication date: January 26, 2012
    Inventors: Kenneth Paul Olive, David Tuveson
  • Treatment of gastrointestinal stromal tumors
    Patent number: 6958335
    Abstract: 4-(4-methylpiperazin-1-ylmethyl)-N-[4-methyl-3-(4-pyridin-3-yl)pyrimidin-2-ylamino)phenyl]-benzamide of the formula I or a pharmaceutically acceptable salt thereof can be used in the treatment of gastrointestinal stromal tumours.
    Type: Grant
    Filed: October 26, 2001
    Date of Patent: October 25, 2005
    Assignees: Novartis AG, Dana-Farber Cancer Institute, Inc., Oregon Health & Science University
    Inventors: Elisabeth Buchdunger, Renaud Capdeville, George Daniel Demetri, Sasa Dimitrijevic, Brian Jay Druker, Jonathan A. Fletcher, Michael C. Heinrich, Heikki Joensuu, Sandra Leta Silberman, David Tuveson
  • Treatment of gastrointestinal stromal tumors
    Publication number: 20040023976
    Abstract: 4-(4-methylpiperazin-1-ylmethyl)-N-[4-methyl-3-(4-pyridin-3-yl)pyrimidin-2-ylamino)phenyl]-benzamide of the formula (I) or a pharmaceutically acceptable salt thereof can be used in the treatment of gastrointestinal stromal tumours.
    Type: Application
    Filed: August 11, 2003
    Publication date: February 5, 2004
    Inventors: Elisabeth Buchdunger, Renaud Capdeville, George Daniel Demetri, Sasa Dimitrijevic, Brian Jay Druker, Jonathan A. Fletcher, Michael C. Heinrich, Heikki Joensuu, Sandra Leta Silberman, David Tuveson