Abstract: The present invention provides methods of preparing 2-amino-6-((1r,4r)-4-phenylcyclohexyl)-5-(3-(trifluoromethyl)benzyl)pyrimidin-4(3H)-one, and 2-amino-6-((1r,4r)-4-phenylcyclohexyl)-5-(3-(trifluoromethyl)benzyl)pyrimidin-4(3H)-one monohydrate, as well as new intermediate compounds.

Abstract: The present invention provides methods of preparing 2-amino-6-((1r,4r)-4-phenylcyclohexyl)-5-(3-(trifluoromethyl)benzyl)pyrimidin-4(3H)-one, and 2-amino-6-((1r,4r)-4-phenylcyclohexyl)-5-(3-(trifluoromethyl)benzyl)pyrimidin-4(3H)-one monohydrate, as well as new intermediate compounds.

Abstract: An antibacterial cleaning composition for hard surfaces is made from a flexible superabsorbent material and an antibacterial agent. The composition can be applied to various liquid and solid surface contaminants, including blood, vomit, fecal matter, urine, glass, food, etc. The composition may be applied to the contaminated hard surface by several methods including pouring, rolling, spraying or foaming. Once cured, the antimicrobial cleaning composition is removed from the surface, taking the contaminant along with it and leaving behind a clean surface.

Abstract: A process for preparing 1-halo-2,7-naphthyridinyl derivatives is described (I), wherein X is Cl or Br; which process comprises the following steps: (i) reaction of a 3-cyano-4-methylpyridine derivative of formula (A): with a compound of formula (II), in the presence of an N,N-dimethylformamide diC1-6alkylacetal; to give an enamine derivative of formula (III), (ii) cyclisation of the enamine of formula (III), to obtain the compound of formula (IV), (iii) reaction of the compound of formula (IV) with a halogenating agent, to obtain a compound of formula (I).

Abstract: A gas dispenser includes a reservoir for holding a liquid, and a chamber in communication with the reservoir. The chamber receives the liquid, and a micro power source generates energy for conversion of the liquid disposed in the chamber. A nozzle defining an orifice in selective communication with the chamber. The nozzle is used to release the converted liquid from the chamber through the orifice.

Abstract: A liquid dispenser includes a reservoir for holding a liquid, and a chamber in communication with the reservoir. The chamber receives the liquid, and a micro power source generates electricity for heating the liquid disposed in the chamber. A nozzle is included for releasing the heated liquid from the chamber through an orifice in the nozzle.

Abstract: A floor-cleaning apparatus includes a cleaning head having a cleaning device, a control handle connected to the cleaning head for controlling the cleaning head and a micro power source in communication with the cleaning device. The micro power source is lightweight, compact, and rechargeable or replaceable for generating energy to power the cleaning device.

Abstract: A breast pad assembly is disclosed wherein one face of the breast pad which faces the breast during use contains a composition comprising a skin benefit ingredient for improving the skin health of a woman's breast and nipple skin. In one embodiment of the invention, the skin health benefit ingredient comprises omega-3 fatty acids which can replace lipids lost from the breast and nipple during breast feeding. The omega-3 fatty acids can also be ingested by the infant to improve systemic development in the infant. In another embodiment, the skin benefit ingredient comprises omega-3 fatty acids and essential fatty acids.

Abstract: A dialyzer header cleaning device composed of: a connecting member for connecting the device to the header, the connecting member having a longitudinal passage with a longitudinal axis; and a flow directing member having first and second opposed ends and a fluid passage extending between a fluid inlet at the first end and a fluid outlet at the second end. The flow directing member has a portion that extends from the second end toward the first end and is held in the longitudinal passage. The flow directing member is manually rotatable about the longitudinal axis relative to the connecting member and is manually movable along the longitudinal axis relative to the connecting member. The fluid outlet of the flow directing member is constructed to eject at least one liquid stream in a direction transverse to the longitudinal axis when fluid is supplied to the fluid inlet.

Abstract: Methods for neutralizing dust mite feces are disclosed. In one embodiment, a botanical extract having a BAPNA-Trypsin Inhibition (IC50×10?3 (%, v/v or w/v) of from about 0.01 to about 500 and a sufficient solubility in water is introduced into water to form an aqueous botanical extract solution. The aqueous botanical extract solution is atomized into an area being treated such that the botanical extract contacts and neutralizes the dust mite feces located in the area. Particularly preferred botanical extracts for use in the botanical extract aqueous solutions of the present invention include Green Tea Extra and Grape Seed Extract.

Abstract: A process for the preparation of a class of phenylalanine enamide derivatives is described: wherein: Ar1 is an optionally substituted aromatic or heteroaromatic group; L2 is a linker group selected from —N(R4)— [where R4 is a hydrogen atom or an optionally substituted straight or branched C1-6alkyl group], —CON(R4)—, or —S(O)2N(R4)—; R1 is a carboxylic acid (—CO2H) or a derivative or biostere thereof; R2 is a hydrogen atom or a C1-6alkyl group; Rx, Ry and Rz which may be the same or different is each an atom or group -L1(Alk1)n(R3)v; and the salts, solvates, hydrates and N-oxides thereof; which comprises reacting a compound of formula (2): wherein: Qa is a group —N(R4)H; and the salts, solvates, hydrates and N-oxides thereof; with a compound Ar1W wherein W is a group selected from X1(wherein X1 is a leaving atom or group), —COX2 (wherein X2 is a halogen atom or a —OH group) or —SO2X3 (in which X3 is a halogen atom).

Abstract: Cleansing wipes comprising a film forming polymeric material and a cleansing agent stored in dry form are disclosed. The cleansing wipes are water disintegratable such that upon contact with water, the cleansing wipes release the cleansing agent and begin to dissolve/disperse into the water. Full dissolution/dispersion of the cleansing wipes occurs in about 60 seconds or less after contact with water to allow for a sufficient time for cleansing of the hands or other skin area.

Abstract: An adjustable viewing frame (27) for use by artists to help compose a view comprises two frame members (10,11) each having two frame links (21,22,23,24) at right angles to one another. The frame links (21,22,23,24) have a rib (30) along one edge over which two C-shape clips (20) engage to hold the two frame members (10,11) together where they overlap. The force exerted by the clips (30) is sufficient to hold the two frame members (10,11) together against disturbances so that the frame (27) thus formed can be held in one hand for viewing purposes, but allows adjustments to be made easily by hand to change the size and/or relative proportions of the frame (27). A scale (40) marked on the frame member (10) allows specific relative proportions to be achieved with certainty and precision.

Abstract: A process for the preparation of a class of phenylalanine enamide derivatives is described: 1

Abstract: An adjustable viewing frame (27) for use by artists to help compose a view comprises two frame members (10,11) each having two frame links (21,22,23,24) at right angles to one another. The frame links (21,22,23,24) have a rib (30) along one edge over which two C-shape clips (20) engage to hold the two frame members (10,11) together where they overlap. The force exerted by the clips (30) is sufficient to hold the two frame members (10,11) together against disturbances so that the frame (27) thus formed can be held in one hand for viewing purposes, but allows adjustments to be made easily by hand to change the size and/or relative proportions of the frame (27). A scale (40) marked on the frame member (10) allows specific relative proportions to be achieved with certainty and precision.

Abstract: Separation of anionic oligosaccharides on a preparative scale with high resolution can be achieved by anionic exchange chromatography using PEI-derivatized supports.