Abstract: The present invention provides compositions and methods to facilitate the identification of compounds that are capable of interacting with a biological macromolecule of interest. In one aspect, a composition is provided that comprises an array of one or more types of chemical compounds attached to a solid support using isocyanate or isothiocyanate chemistry, wherein the density of the array of compounds is at least 1000 spots per cm2.

Abstract: The present invention provides compositions and methods to facilitate the identification of compounds that are capable of interacting with a biological macromolecule of interest. In one aspect, a composition is provided that comprises an array of one or more types of chemical compounds attached to a solid support using isocyanate or isothiocyanate chemistry, wherein the density of the array of compounds is at least 1000 spots per cm2.

Abstract: A sealant melter incorporates a sealant block feed assembly that reduces the labor required to feed sealant blocks to the sealant tank of the melter and that reduces or even eliminates the risk that hot liquid sealant will splash out of the sealant tank when sealant blocks are fed into it. The sealant block feed assembly preferably includes a top-fed splash box and a conveyor assembly for feeding sealant blocks to the splash box from a towing/storage vehicle or the like. The splash box incorporates internal guards in the form of counterbalanced flaps that prevent hot liquid sealant from splashing out of the splash box when the sealant blocks are fed into it from above. The conveyor assembly includes a conveyor that is selectively controllable, either from the towing/storage vehicle or from curbside, to receive sealant blocks and to selectively feed the received sealant blocks to the splash box.

Abstract: Non-tumorigenic cell lines capable of indefinite growth in serum-free media are disclosed. The cell lines are capable of expressing exogenously introduced genes, and may be derived from mouse embryo cells. Methods for producing proteins utilizing these cell lines, and methods for selectively controlling the growth of the cell lines are also disclosed.

Abstract: Non-tumorigenic cell lines capable of indefinite growth in serum-free media are disclosed. The cell lines are capable of expressing exogenously introduced genes, and may be derived from mouse embryo cells. Methods for producing proteins utilizing these cell lines, and methods for selectively controlling the growth of the cell lines are also disclosed.

Abstract: A three dimensional integrated circuit interconnect for connecting a plurality of chips in a module with a standard footprint for pin grid array or quad flat pack mounting. Each IC is mounted on a custom interconnect slice and tested. The slices are stacked together with electrical connections from one slice layer to the next. The module may use multi-layer ceramic slices or printed circuit board materials.

Abstract: An adjustable pocket printing platen is disclosed for use with the printing platen of a prior art type of silk screen printing machine. The adjustable pocket printing platen includes a frame having a pair of spaced, transverse rails having end flanges positioned to bottomly underly the marginal edges of the machine platen. Thumb screws extend through the bottom flanges to lock the pocket printing platen to the machine platen in any longitudinally adjusted position. A small platen transversely rides along the transverse rails and is sized to receive and support the pocket of a garment thereupon. Set screws extend through marginal edges of the small platen to lock the platen to the transverse rails in any desired transversely adjusted position. The top surface of the small platen extends above the top surface of the machine platen to receive the printing screen when it is lowered to apply a screened design to a garment pocket.