Patents by Inventor David W. Bauer

David W. Bauer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for Preparing Chiral Compounds
    Publication number: 20140187794
    Abstract: The present invention is directed to a 2-deoxyribose-5-phosphate aldolase (DERA) chemoenzymatic process for making chiral compounds.
    Type: Application
    Filed: December 20, 2013
    Publication date: July 3, 2014
    Applicant: Pfizer Inc.
    Inventors: David W. Bauer, Padraig M. O'Neill, Timothy J. Watson, Shanghui Hu
  • Process for preparing chiral compounds
    Patent number: 8642783
    Abstract: The present invention is directed to a 2-deoxyribose-5-phosphate aldolase (DERA) chemoenzymatic process for making chiral compounds.
    Type: Grant
    Filed: July 23, 2008
    Date of Patent: February 4, 2014
    Assignee: Pfizer Inc.
    Inventors: David W. Bauer, Padraig M. O'Neill, Timothy J. Watson, Shanghui Hu
  • Process for Preparing Chiral Compounds
    Publication number: 20110118476
    Abstract: The present invention is directed to a 2-deoxyribose-5-phosphate aldolase (DERA) chemoenzymatic process for making chiral compounds.
    Type: Application
    Filed: July 23, 2008
    Publication date: May 19, 2011
    Inventors: David W. Bauer, Padraig M. O'Nell, Timothy J. Watson, Shanghui Hu
  • Oomycete-resistant transgenic plants by virtue of pathogen-induced expression of a heterologous hypersensitive response elicitor
    Patent number: 7041876
    Abstract: The present invention relates to a chimeric gene that includes a first DNA molecule encoding a hypersensitive response elicitor protein or polypeptide, a promoter operably linked 5? to the first DNA molecule to induce transcription of the first DNA molecule in response to activation of the promoter by an oomycete, and a 3? regulatory region operably linked to the first DNA molecule. Also disclosed are an expression system and a host cell containing the chimeric gene. The present invention also relates to a transgenic plant resistant to disease resulting from oomycete infection, the transgenic plant including the chimeric gene, wherein the promoter induces transcription of the first DNA molecule in response to infection of the plant by an oomycete. Transgenic seeds and transgenic cultivars obtained from the transgenic plant are also disclosed. Additional aspects of the present invention include methods of making a recombinant plant cell and a transgenic plant.
    Type: Grant
    Filed: January 26, 2001
    Date of Patent: May 9, 2006
    Assignee: Cornell Research Foundation, Inc.
    Inventors: Steven V. Beer, David W. Bauer
  • Recombinant constructs and systems for secretion of proteins via type III secretion systems
    Patent number: 6596509
    Abstract: One aspect of the present invention relates to a DNA construct that contains a first DNA molecule encoding a functional type III secretion system, a promoter, and a second DNA molecule encoding a protein or polypeptide capable of being secreted by the type III secretion system. The second DNA molecule is operably coupled to the promoter so that upon introduction of the DNA construct into a host cell, the encoded protein or polypeptide and the type III secretion system are expressed and the encoded protein or polypeptide is secreted. Another aspect of the present invention relates to a system that includes (i) a first DNA construct having a first DNA molecule encoding a functional type III secretion system and (ii) a second DNA construct having a promoter operably coupled to a second DNA molecule encoding a protein or polypeptide capable of being secreted by the type III secretion system.
    Type: Grant
    Filed: July 9, 1999
    Date of Patent: July 22, 2003
    Assignee: Cornell Research Foundation, Inc.
    Inventors: David W. Bauer, Steven V. Beer, Adam J. Bogdanove, Alan Collmer, Jong Hyun Ham
  • Peer-to-peer electronic marketplace and systems and methods for conducting transactions therein
    Publication number: 20020069117
    Abstract: A peer-to-peer electronic marketplace and systems and methods for conducting transactions therein is provided. More particular, the electronic marketplace includes member systems and a market administrator. The market administrator controls the membership to a market of goods/services. Member systems communicate directly with each other using mobile agents without having to go through the market administrator. The mobile agents not only allow the users to remain anonymous, but also efficiently locate buyers and sellers of goods/services.
    Type: Application
    Filed: December 1, 2000
    Publication date: June 6, 2002
    Inventors: Christopher D. Carothers, Cheng Hsu, David W. Bauer
  • Oomycete-resistant transgenic plants by virtue of pathogen-induced expression of a heterologous hypersensitive response elicitor
    Publication number: 20020069434
    Abstract: The present invention relates to a chimeric gene that includes a first DNA molecule encoding a hypersensitive response elicitor protein or polypeptide, a promoter operably linked 5′ to the first DNA molecule to induce transcription of the first DNA molecule in response to activation of the promoter by an oomycete, and a 3′ regulatory region operably linked to the first DNA molecule. Also disclosed are an expression system and a host cell containing the chimeric gene. The present invention also relates to a transgenic plant resistant to disease resulting from oomycete infection, the transgenic plant including the chimeric gene, wherein the promoter induces transcription of the first DNA molecule in response to infection of the plant by an oomycete. Transgenic seeds and transgenic cultivars obtained from the transgenic plant are also disclosed. Additional aspects of the present invention include methods of making a recombinant plant cell and a transgenic plant.
    Type: Application
    Filed: January 26, 2001
    Publication date: June 6, 2002
    Inventors: Steven V. Beer, David W. Bauer
  • Elicitor of the hypersensitive response in plants
    Patent number: 6174717
    Abstract: The nucleic acid and amino acid sequences for proteinaceous elicitors of the plant defense reaction known as the hypersensitive response are described along with methods for preparation and processes for inactivation.
    Type: Grant
    Filed: May 5, 1997
    Date of Patent: January 16, 2001
    Assignee: Cornell Research Foundation, Inc.
    Inventors: Steven V. Beer, Zhong-Min Wei, David W. Bauer, Alan Collmer, Sheng-Yang He, Ron Laby
  • Elicitor of the hypersensitive response in plants
    Patent number: 5849868
    Abstract: The nucleic acid and amino acid sequences for proteinaceous elicitors of the plant defense reaction known as the hypersensitive response are described along with methods for preparation and processes for inactivation.
    Type: Grant
    Filed: February 23, 1994
    Date of Patent: December 15, 1998
    Assignee: Cornell Research Foundation, Inc.
    Inventors: Steven V. Beer, Zhong-Min Wei, David W. Bauer, Alan Collmer, Sheng-Yang He, Ron Laby