Patents by Inventor David W. Cushman

David W. Cushman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Carboxyalkylacylamino acids
    Patent number: 4146639
    Abstract: New carboxyalkylacylamino acids which have the general formula ##STR1## are useful as angiotensin converting enzyme inhibitors.
    Type: Grant
    Filed: May 4, 1978
    Date of Patent: March 27, 1979
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Miguel A. Ondetti, David W. Cushman
  • Method for alleviating angiotensin related hypertension
    Patent number: 4140786
    Abstract: A method for alleviating or reducing angiotensin related hypertension in hypertensive mammals comprises administering to such hypertensive mammals an effective amount of an angiotensin converting enzyme inhibitor selected from a group of mercaptoacyl aminoacids.
    Type: Grant
    Filed: March 9, 1978
    Date of Patent: February 20, 1979
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Miguel A. Ondetti, David W. Cushman
  • Method for alleviating angiotensin related hypertension
    Patent number: 4140797
    Abstract: A method for alleviating or reducing angiotensin related hypertension in hypertensive mammals comprises administering to such hypertensive mammals an effective amount of an angiotensin converting enzyme inhibitor selected from a group of mercaptoacyl aminoacids.
    Type: Grant
    Filed: March 9, 1978
    Date of Patent: February 20, 1979
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Miguel A. Ondetti, David W. Cushman
  • Reduction of blood pressure with carboxyalkylacyl-pipecolic acid derivatives
    Patent number: 4128653
    Abstract: New carboxyalkylacylamino acids which are derivatives of proline, pipecolic acid and azetidine-2-carboxylic acid and have the general formula ##STR1## are useful as angiotensin converting enzyme inhibitors.
    Type: Grant
    Filed: February 11, 1977
    Date of Patent: December 5, 1978
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: David W. Cushman, Miguel A. Ondetti
  • Method for alleviating angiotensin related hypertension
    Patent number: 4112119
    Abstract: A method for alleviating or reducing angiotensin related hypertension in hypertensive mammals comprises administering to such hypertensive mammals an effective amount of an angiotensin converting enzyme inhibitor selected from a group of mercaptoacyl aminoacids.
    Type: Grant
    Filed: March 3, 1977
    Date of Patent: September 5, 1978
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Miguel Angel Ondetti, David W. Cushman
  • Proline derivatives and related compounds
    Patent number: 4105776
    Abstract: New proline derivatives and related compounds which have the general formula ##STR1## are useful as angiotensin converting enzyme inhibitors.
    Type: Grant
    Filed: December 22, 1976
    Date of Patent: August 8, 1978
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Miguel Angel Ondetti, David W. Cushman
  • Carboxyalkylacylamino acids
    Patent number: 4105789
    Abstract: New carboxyalkylacylamino acids which have the general formula ##STR1## are useful as angiotensin converting enzyme inhibitors.
    Type: Grant
    Filed: May 10, 1976
    Date of Patent: August 8, 1978
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Miguel Angel Ondetti, David W. Cushman
  • N-carboxyalkanoyl derivatives of azetidine-2-carboxylic acid
    Patent number: 4086338
    Abstract: New carboxyalkylacylamino acids which are derivatives of proline, pipecolic acid and azetidine-2-carboxylic acid and have the general formula ##STR1## are useful as angiotensin converting enzyme inhibitors.
    Type: Grant
    Filed: February 11, 1977
    Date of Patent: April 25, 1978
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: David W. Cushman, Miguel Angel Ondetti
  • Compounds and method for alleviating angiotensin related hypertension
    Patent number: 4053651
    Abstract: A method for alleviating or reducing angiotensin related hypertension in hypertensive mammals comprises administering to such hypertensive mammals an effective amount of an angiotensin converting enzyme inhibitor selected from a group of mercaptoacyl aminoacids.
    Type: Grant
    Filed: May 10, 1976
    Date of Patent: October 11, 1977
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Miguel Angel Ondetti, David W. Cushman
  • Carboxyacylproline derivatives
    Patent number: 4052511
    Abstract: New carboxyalkylacylamino acids which are derivatives of proline, pipecolic acid and azetidine-2-carboxylic acid and have the general formula ##STR1## are useful as angiotensin converting enzyme inhibitors.
    Type: Grant
    Filed: February 13, 1976
    Date of Patent: October 4, 1977
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: David W. Cushman, Miguel Angel Ondetti
  • Azetidine-2-carboxylic acid derivatives
    Patent number: 4046889
    Abstract: New proline derivatives and related compounds which have the general formula ##STR1## are useful as angiotensin converting enzyme inhibitors.
    Type: Grant
    Filed: February 13, 1976
    Date of Patent: September 6, 1977
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Miguel Angel Ondetti, David W. Cushman