Patents by Inventor David W. Holdsworth

David W. Holdsworth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11402515
    Abstract: An intraoperative imaging system combines a gamma probe and an ultrasound probe. The probes are linked to provide co-registration of gamma radiation detected by the gamma probe with an image acquired by the ultrasound probe. The gamma probe has a converging collimator made of a metal block having a plurality of channels therein, which converge from an output face toward an input face. Each channel extends between and opens out at the faces such that openings at the input face have smaller cross-sectional areas than openings at the output face so that each channel tapers inwardly from the output face to the input face. The collimator has an external focal point distant from the input face. The system improves identification and localization of cancerous cells, facilitating more accurate biopsy data and more complete surgical resection. The gamma probe increases sensitivity, while maintaining spatial resolution, and increasing depth of view.
    Type: Grant
    Filed: May 31, 2017
    Date of Patent: August 2, 2022
    Inventors: David W. Holdsworth, Mohammad Ali Tavallaei, John Matheson, Asha Parekh
  • Publication number: 20200100901
    Abstract: A bone cement mold for a bone cement spacer, the bone cement mold including: a first mold component defining a first cavity shaped to form at least a majority of a head portion of the spacer; a second mold component defining a second cavity shaped to form a first part of a stem portion of the spacer; a third mold component defining a third cavity shaped to form a second part of the stem portion of the spacer; the second mold component and the third mold component combining to define a cavity shaped to form at least a majority of the stem portion; an abutting combination of the first mold component, second mold component, and third component defining a communicative cavity shaped to form the head portion integrally connected with the stem portion. Bone cement spacers formed from the bone cement mold, and computer methods and systems for selecting and operating the bone cement mold are also described.
    Type: Application
    Filed: June 16, 2017
    Publication date: April 2, 2020
    Inventors: Brent A. LANTING, Matthew G. TEETER, Hristo NIKOLOV, David W. HOLDSWORTH, Mohammad Ali TAVALLAEI, John MATHESON, Asha PAREKH
  • Patent number: 10557911
    Abstract: 3D printing in MRI-compatible plastic resin has been used to fabricate and implement a geometric distortion phantom for MRI and CT imaging. The sparse grid structure provides a rigid and accurate phantom with identifiable intersections that are larger than the supporting members, which produces images that are amenable to fully automated quantitative analysis using morphometric erosion, greyscale segmentation and centroiding. This approach produces a 3D vector map of geometric distortion that is useful in clinical applications where geometric accuracy is important, either in routine quality assurance or as a component of distortion correction utilities.
    Type: Grant
    Filed: December 6, 2018
    Date of Patent: February 11, 2020
    Inventor: David W. Holdsworth
  • Publication number: 20190154845
    Abstract: An intraoperative imaging system combines a gamma probe and an ultrasound probe. The probes are linked to provide co-registration of gamma radiation detected by the gamma probe with an image acquired by the ultrasound probe. The gamma probe has a converging collimator made of a metal block having a plurality of channels therein, which converge from an output face toward an input face. Each channel extends between and opens out at the faces such that openings at the input face have smaller cross-sectional areas than openings at the output face so that each channel tapers inwardly from the output face to the input face. The collimator has an external focal point distant from the input face. The system improves identification and localization of cancerous cells, facilitating more accurate biopsy data and more complete surgical resection. The gamma probe increases sensitivity, while maintaining spatial resolution, and increasing depth of view.
    Type: Application
    Filed: May 31, 2017
    Publication date: May 23, 2019
    Inventors: David W. Holdsworth, Mohammad Ali Tavallaei, John Matheson, Asha Parekh
  • Publication number: 20190107596
    Abstract: 3D printing in MRI-compatible plastic resin has been used to fabricate and implement a geometric distortion phantom for MRI and CT imaging. The sparse grid structure provides a rigid and accurate phantom with identifiable intersections that are larger than the supporting members, which produces images that are amenable to fully automated quantitative analysis using morphometric erosion, greyscale segmentation and centroiding. This approach produces a 3D vector map of geometric distortion that is useful in clinical applications where geometric accuracy is important, either in routine quality assurance or as a component of distortion correction utilities.
    Type: Application
    Filed: December 6, 2018
    Publication date: April 11, 2019
    Inventors: David W. Holdsworth, Matthew G. Teeter, Jacques S. Milner, Steven I. Pollmann, Maria Drangova
  • Patent number: 10180483
    Abstract: 3D printing in MRI-compatible plastic resin has been used to fabricate and implement a geometric distortion phantom for MRI and CT imaging. The sparse grid structure provides a rigid and accurate phantom with identifiable intersections that are larger than the supporting members, which produces images that are amenable to fully automated quantitative analysis using morphometric erosion, greyscale segmentation and centroiding. This approach produces a 3D vector map of geometric distortion that is useful in clinical applications where geometric accuracy is important, either in routine quality assurance or as a component of distortion correction utilities.
    Type: Grant
    Filed: April 23, 2015
    Date of Patent: January 15, 2019
    Inventors: David W Holdsworth, Matthew G. Teeter, Jacques S. Milner, Steven I. Pollmann, Maria Drangova
  • Publication number: 20150309149
    Abstract: 3D printing in MRI-compatible plastic resin has been used to fabricate and implement a geometric distortion phantom for MRI and CT imaging. The sparse grid structure provides a rigid and accurate phantom with identifiable intersections that are larger than the supporting members, which produces images that are amenable to fully automated quantitative analysis using morphometric erosion, greyscale segmentation and centroiding. This approach produces a 3D vector map of geometric distortion that is useful in clinical applications where geometric accuracy is important, either in routine quality assurance or as a component of distortion correction utilities.
    Type: Application
    Filed: April 23, 2015
    Publication date: October 29, 2015
    Inventors: David W. Holdsworth, Matthew G. Teeter, Jacques S. Milner, Steven I. Pollmann, Maria Drangova
  • Patent number: 5485831
    Abstract: A technique for pulsed-injection of radiographic contrast agent uses a pressurized source of contrast agent interrupted by a rotary valve at rates ranging from 1 to 30 Hz. This produces well-defined boli at the end of the catheter. The position of these boli is recorded by a digital radiographic system and analyzed to produce quantitative measurements of blood velocity and flow rate throughout the cardiac cycle.
    Type: Grant
    Filed: November 30, 1993
    Date of Patent: January 23, 1996
    Assignee: University Hospital (London) Development Corporation
    Inventors: David W. Holdsworth, Maria Drangova, Aaron Fenster