Abstract: A biomedical lead conductor cable formed of a core wire strand and a plurality of perimeter wire strands wrapped in a helical pattern around the core wire strand, wherein the core wire strand is formed of M wires and the perimeter wire strands are formed of N wires. The core wire strand is formed of a first core wire and M-1 first peripheral wires helically wrapped about the first core wire in a non-overlapping manner, the first core wire having a mechanical strength exceeding the mechanical strength of each first peripheral wire and an electrical conductivity lower than the electrical conductivity of each first peripheral wire.

Abstract: A body compatible stent is formed of multiple filaments arranged in two sets of oppositely directed helical windings interwoven with one another in a braided configuration. Each of the filaments is a composite including a central core and a case surrounding the core. In the more preferred version, the core is formed of a radiopaque and relatively ductile material, e.g. tantalum or platinum. The outer case is formed of a relatively resilient material, e.g. a cobalt/chromium based alloy. Favorable mechanical characteristics of the stent are determined by the case, while the core enables in vivo imaging of the stent. The composite filaments are formed by a drawn filled tubing process in which the core is inserted into a tubular case of a diameter substantially more than the intended final filament diameter. The composite filament is cold-worked in several steps to reduce its diameter, and annealed between successive cold-working steps.

Abstract: A body compatible stent is formed of multiple filaments arranged in at least two sets of oppositely directed helical windings interwoven with one another in a braided configuration. Each of the filaments is a composite including a central core and a case surrounding the core. In the more preferred version, the core is formed of a radiopaque and relatively ductile material, e.g. tantalum or platinum. The outer case is formed of a relatively resilient material, e.g. a cobalt/chromium based alloy. Favorable mechanical characteristics of the stent are determined by the case, while the core enables in vivo imaging of the stent. The composite filaments are formed by a drawn filled tubing process in which the core is inserted into a tubular case of a diameter substantially more than the intended final filament diameter. The composite filament is cold-worked in several steps to reduce its diameter, and annealed between successive cold-working steps.

Abstract: A body compatible stent is formed of multiple filaments arranged in two sets of oppositely directed helical windings interwoven with one another in a braided configuration. Each of the filaments is a composite including a central core and a case surrounding the core. In the more preferred version, the core is formed of a radiopaque and relatively ductile material having a linear attenuation coefficient of at least 25 cm.sup.-1 at 100 KeV, e.g. tantalum or platinum. The outer case is formed of a relatively resilient material, e.g. a cobalt/chromium based alloy. Favorable mechanical characteristics of the stent are determined by the case, while the core enables in vivo imaging of the stent. Alternative composite filaments employ an intermediate barrier layer between the case and core formed for example of tantalum, niobium or platinum. To improve compatibility, a biocompatible cover layer can surround the case.

Abstract: An adapter for extending a sensing and stimulation delivery lead in a body stimulation system, such as a cardiac pacer or cardioverter defibrillator, includes a resilient, electrically insulative housing with a longitudinal barrel extended through the majority of the housing length for the insertion of a lead terminal connector. Two spaced apart transverse bores are formed in the housing, open to barrel and to the housing exterior. Two connector assemblies are mounted in the housing and positioned to receive respective pin and ring terminals of the lead when inserted into the barrel. Each connector assembly can be adjusted to secure the lead in the housing, by a tool inserted through one of the transverse bores. Each connector assembly is isolated from the housing exterior by a seal means mounted in the associated bore. Each seal means includes a seal member elastically deformable to admit a tool to the associated connector assembly via a passage through the seal member.

Abstract: A biocompatible covering, soluble in body fluids, surrounds the fixation helix of an implantable cardiac electrode as the electrode, and its adjoining lead, are inserted intravenously to a selected cardiac chamber. The covering size and shape are selected for protection of blood vessels and other body tissues during insertion, and for exposure of the fixation element shortly after its proper positioning. The covering may be applied to the fixation element by a dip coating process, or formed separately by casting or injection molding, for later attachment to the lead distal end using an adhesive.

Abstract: A biocompatible covering, soluble in body fluids, surrounds the fixation helix of an implantable cardiac electrode as the electrode, and its adjoining lead, are inserted intravenously to a selected cardiac chamber. The covering size and shape are selected for protection of blood vessels and other body tissues during insertion, and for exposure of the fixation element shortly after its proper positioning. The covering may be applied to the fixation element by a dip coating process, or formed separately by casting or injection molding, for later attachment to the lead distal end using an adhesive.

Abstract: A catheter assembly designed for long term or short term implantation in an animal body comprising a flexible tube of a biocompatible polymeric material in which plural electrical conductors are helically wound at a predetermined pitch with the conductors being laterally offset from one another and totally buried between the walls of the tube whereby many conductive signal paths can be established through the catheter without increasing its overall diameter. The inclusion of the helically wound conductors in the walls of the tube also allows the torque transfer, flexibility and structural properties to be tailored to fit a variety of applications. Such a catheter may be used as a cardiac pacer lead assembly or as an instrument for carrying out various diagnostic catheterization procedures.