Patents by Inventor David W. Miles

David W. Miles has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240141824
    Abstract: The power system includes a compression ignition engine configured to combust intake gas; an intake arrangement configured to intake charge air; an exhaust arrangement to receive a first portion of the exhaust; an EGR arrangement to receive a second portion of the exhaust as EGR gas; a first mixer to selectively mix a first portion of the EGR gas and the charge air as mixed gas; an intake heat exchanger positioned upstream or downstream of the first mixer and respectively configured to receive one of the intake charge air or the mixed gas such that heat is exchanged with engine coolant; a second mixer positioned downstream of the first mixer and the intake heat exchanger and configured to selectively mix a second portion of the EGR gas and the mixed gas to form the intake gas; and an intake manifold configured to direct the intake gas into the engine.
    Type: Application
    Filed: September 6, 2023
    Publication date: May 2, 2024
    Inventors: Craig W. Lohmann, Jacob M. Rosswurm, Scott R. Miles, David A. Arntz, Darrin L. Treptow
  • Publication number: 20230405079
    Abstract: Provided herein are stable lisinopril oral liquid formulations. Also provided herein are methods of using lisinopril oral liquid formulations for the treatment of certain diseases including hypertension, heart failure and acute myocardial infarction.
    Type: Application
    Filed: August 16, 2023
    Publication date: December 21, 2023
    Inventors: Gerold L. MOSHER, David W. MILES
  • Patent number: 11795241
    Abstract: The present invention relates to compositions comprising fractionated alkylated cyclodextrin compositions having a single degree of substitution, and processes for preparing and using the same.
    Type: Grant
    Filed: November 24, 2020
    Date of Patent: October 24, 2023
    Assignee: CyDex Pharmaceuticals, Inc.
    Inventors: Vincent D. Antle, Charles Alan Watson, David W. Miles
  • Patent number: 11771733
    Abstract: Provided herein are stable lisinopril oral liquid formulations. Also provided herein are methods of using lisinopril oral liquid formulations for the treatment of certain diseases including hypertension, heart failure and acute myocardial infarction.
    Type: Grant
    Filed: October 21, 2021
    Date of Patent: October 3, 2023
    Assignee: SILVERGATE PHARMACEUTICALS, INC.
    Inventors: Gerold L. Mosher, David W. Miles
  • Publication number: 20220111000
    Abstract: Provided herein are stable lisinopril oral liquid formulations. Also provided herein are methods of using lisinopril oral liquid formulations for the treatment of certain diseases including hypertension, heart failure and acute myocardial infarction.
    Type: Application
    Filed: October 21, 2021
    Publication date: April 14, 2022
    Inventors: Gerold L. MOSHER, David W. MILES
  • Publication number: 20220047549
    Abstract: Provided herein are stable enalapril oral liquid formulations. Also provided herein are methods of using enalapril oral liquid formulations for the treatment of certain diseases including hypertension, heart failure and asymptomatic left ventricular dysfunction.
    Type: Application
    Filed: October 29, 2021
    Publication date: February 17, 2022
    Inventors: Gerold L. MOSHER, David W. MILES
  • Patent number: 11179434
    Abstract: Provided herein are stable lisinopril oral liquid formulations. Also provided herein are methods of using lisinopril oral liquid formulations for the treatment of certain diseases including hypertension, heart failure and acute myocardial infarction.
    Type: Grant
    Filed: March 5, 2021
    Date of Patent: November 23, 2021
    Assignee: Silvergate Pharmaceuticals Inc.
    Inventors: Gerold L. Mosher, David W. Miles
  • Patent number: 11173141
    Abstract: Provided herein are stable enalapril oral liquid formulations. Also provided herein are methods of using enalapril oral liquid formulations for the treatment of certain diseases including hypertension, heart failure and asymptomatic left ventricular dysfunction.
    Type: Grant
    Filed: June 3, 2021
    Date of Patent: November 16, 2021
    Assignee: Azurity Pharmaceuticals, Inc.
    Inventors: Gerold L. Mosher, David W. Miles
  • Patent number: 11141405
    Abstract: Provided herein are stable enalapril oral liquid formulations. Also provided herein are methods of using enalapril oral liquid formulations for the treatment of certain diseases including hypertension, heart failure and asymptomatic left ventricular dysfunction.
    Type: Grant
    Filed: April 12, 2021
    Date of Patent: October 12, 2021
    Assignee: AZURITY PHARMACEUTICALS, INC.
    Inventors: Gerold L. Mosher, David W. Miles
  • Publication number: 20210299092
    Abstract: Provided herein are stable enalapril oral liquid formulations. Also provided herein are methods of using enalapril oral liquid formulations for the treatment of certain diseases including hypertension, heart failure and asymptomatic left ventricular dysfunction.
    Type: Application
    Filed: June 3, 2021
    Publication date: September 30, 2021
    Inventors: Gerold L. Mosher, David W. Miles
  • Publication number: 20210251956
    Abstract: Provided herein are stable enalapril oral liquid formulations. Also provided herein are methods of using enalapril oral liquid formulations for the treatment of certain diseases including hypertension, heart failure and asymptomatic left ventricular dysfunction.
    Type: Application
    Filed: April 12, 2021
    Publication date: August 19, 2021
    Inventors: Gerold L. Mosher, David W. Miles
  • Publication number: 20210187055
    Abstract: Provided herein are stable lisinopril oral liquid formulations. Also provided herein are methods of using lisinopril oral liquid formulations for the treatment of certain diseases including hypertension, heart failure and acute myocardial infarction.
    Type: Application
    Filed: March 5, 2021
    Publication date: June 24, 2021
    Inventors: Gerold L. MOSHER, David W. MILES
  • Patent number: 11040023
    Abstract: Provided herein are stable enalapril oral liquid formulations. Also provided herein are methods of using enalapril oral liquid formulations for the treatment of certain diseases including hypertension, heart failure and asymptomatic left ventricular dysfunction.
    Type: Grant
    Filed: January 15, 2021
    Date of Patent: June 22, 2021
    Assignee: SILVERGATE PHARMACEUTICALS, INC.
    Inventors: Gerold L. Mosher, David W. Miles
  • Publication number: 20210147582
    Abstract: The present invention relates to compositions comprising fractionated alkylated cyclodextrin compositions having a single degree of substitution, and processes for preparing and using the same.
    Type: Application
    Filed: November 24, 2020
    Publication date: May 20, 2021
    Inventors: Vincent D. Antle, Charles Alan Watson, David W. Miles
  • Publication number: 20210137882
    Abstract: Provided herein are stable enalapril oral liquid formulations. Also provided herein are methods of using enalapril oral liquid formulations for the treatment of certain diseases including hypertension, heart failure and asymptomatic left ventricular dysfunction.
    Type: Application
    Filed: January 15, 2021
    Publication date: May 13, 2021
    Inventors: Gerold L. Mosher, David W. Miles
  • Patent number: 10940177
    Abstract: Provided herein are stable lisinopril oral liquid formulations. Also provided herein are methods of using lisinopril oral liquid formulations for the treatment of certain diseases including hypertension, heart failure and acute myocardial infarction.
    Type: Grant
    Filed: March 18, 2020
    Date of Patent: March 9, 2021
    Assignee: SILVERGATE PHARMACEUTICALS, INC.
    Inventors: Gerold L. Mosher, David W. Miles
  • Patent number: 10918621
    Abstract: Provided herein are stable enalapril oral liquid formulations. Also provided herein are methods of using enalapril oral liquid formulations for the treatment of certain diseases including hypertension, heart failure and asymptomatic left ventricular dysfunction.
    Type: Grant
    Filed: August 12, 2020
    Date of Patent: February 16, 2021
    Assignee: SILVERGATE PHARMACEUTICALS, INC.
    Inventors: Gerold L. Mosher, David W. Miles
  • Patent number: 10851184
    Abstract: The present invention relates to compositions comprising fractionated alkylated cyclodextrin compositions having a single degree of substitution, and processes for preparing and using the same.
    Type: Grant
    Filed: August 21, 2015
    Date of Patent: December 1, 2020
    Assignee: CyDex Pharmaceuticals, Inc.
    Inventors: Vincent D. Antle, Charles Alan Watson, David W. Miles
  • Publication number: 20200368200
    Abstract: Provided herein are stable enalapril oral liquid formulations. Also provided herein are methods of using enalapril oral liquid formulations for the treatment of certain diseases including hypertension, heart failure and asymptomatic left ventricular dysfunction.
    Type: Application
    Filed: August 12, 2020
    Publication date: November 26, 2020
    Inventors: Gerold L. MOSHER, David W. MILES
  • Patent number: 10799476
    Abstract: Provided herein are stable enalapril oral liquid formulations. Also provided herein are methods of using enalapril oral liquid formulations for the treatment of certain diseases including hypertension, heart failure and asymptomatic left ventricular dysfunction.
    Type: Grant
    Filed: May 26, 2020
    Date of Patent: October 13, 2020
    Assignee: Silvergate Pharmaceuticals, Inc.
    Inventors: Gerold L. Mosher, David W. Miles