Patents by Inventor David W. Old

David W. Old has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted gamma lactams as therapeutic agents
    Patent number: 8377984
    Abstract: Disclosed herein is a compound represented by the formula: Methods, compositions, and medicaments related to these compounds are also disclosed.
    Type: Grant
    Filed: January 16, 2009
    Date of Patent: February 19, 2013
    Assignee: Allergan, Inc.
    Inventor: David W. Old
  • N,N-DIALKYLALKYLENYL ESTERS, COMPOSITIONS THEREOF, AND METHODS FOR USE THEREOF
    Publication number: 20130029992
    Abstract: The invention provides well defined N,N-dialkylalkenyl ester compounds for treating glaucoma or ocular hypertension. The esters of the invention are particularly advantageous due to their stability in aqueous solutions.
    Type: Application
    Filed: July 25, 2012
    Publication date: January 31, 2013
    Applicant: Allergan, Inc.
    Inventors: Robert M. Burk, David W. Old
  • Therapeutic substituted lactams
    Patent number: 8362054
    Abstract: Therapeutic compounds, compositions, methods, and medicaments related thereto are disclosed herein.
    Type: Grant
    Filed: February 8, 2008
    Date of Patent: January 29, 2013
    Assignee: Allergan, Inc.
    Inventors: David W. Old, Wha Bin Im, Vinh X. Ngo
  • THERAPEUTIC COMPOUNDS
    Publication number: 20130005767
    Abstract: Disclosed herein are compounds of the formula or salts or bioisosteres thereof. Therapeutic methods, medicaments, and compositions related thereto are also disclosed.
    Type: Application
    Filed: September 14, 2012
    Publication date: January 3, 2013
    Applicant: Allergan, Inc.
    Inventors: David W. Old, Vinh X. Ngo
  • Therapeutic compounds
    Patent number: 8338637
    Abstract: Disclosed herein are compounds of the formula or salts or bioisosteres thereof. Therapeutic methods, medicaments, and compositions related thereto are also disclosed.
    Type: Grant
    Filed: August 6, 2008
    Date of Patent: December 25, 2012
    Assignee: Allergan, Inc.
    Inventors: David W. Old, Vinh X. Ngo
  • Therapeutic compounds
    Patent number: 8252788
    Abstract: Compounds comprising or a pharmaceutically acceptable salt or a prodrug thereof are disclosed, wherein a dashed line represents the presence or absence of a bond; and, wherein Y, A, R, D, and n are as described. Methods, compositions, and medicaments related thereto are also disclosed.
    Type: Grant
    Filed: May 13, 2009
    Date of Patent: August 28, 2012
    Assignee: Allergan, Inc.
    Inventors: David W. Old, Vinh X. Ngo
  • Substituted beta-lactams
    Patent number: 8202855
    Abstract: Disclosed herein is a compound comprising a formula or a pharmaceutically acceptable salt or a prodrug or a metabolite thereof; Y is A is —(CH2)6—, cis —CH2CH?CH—(CH2)3—, or —CH2C?C—(CH2)3—, wherein 1 or 2 carbon atoms may be substituted with S or O; or A is —(CH2)m—Ar—(CH2)o— wherein Ar is interarylene or heterointerarylene, the sum of m and o is from 1 to 4, and wherein one CH2 may be substituted with S or O; and D is aryl or heteroaryl. Methods of use are also disclosed.
    Type: Grant
    Filed: March 2, 2009
    Date of Patent: June 19, 2012
    Assignee: Allergan, Inc
    Inventor: David W. Old
  • Therapeutic substituted cyclic lactams
    Patent number: 8198315
    Abstract: Disclosed and described herein is a compound having a formula (I) therapeutic methods, medicaments, and compositions related thereto are also disclosed.
    Type: Grant
    Filed: May 19, 2008
    Date of Patent: June 12, 2012
    Assignee: Allergan, Inc.
    Inventor: David W. Old
  • Therapeutic amides
    Patent number: 8198318
    Abstract: Compounds comprising or a pharmaceutically acceptable salt or a prodrug thereof, are disclosed, wherein G, E, B, Y, and A are as described. Methods, compositions, and medicaments related thereto are also disclosed.
    Type: Grant
    Filed: March 16, 2009
    Date of Patent: June 12, 2012
    Assignee: Allergen, Inc.
    Inventors: David W. Old, Robert M. Burk, Todd Gac
  • Therapeutic lactams
    Patent number: 8124648
    Abstract: Compounds comprising or a pharmaceutically acceptable salt or a prodrug thereof, are disclosed, wherein J1, J2, B, Y, and A are as described. Methods, compositions, and medicaments related thereto are also disclosed.
    Type: Grant
    Filed: May 13, 2009
    Date of Patent: February 28, 2012
    Assignee: Allergan, Inc.
    Inventors: David W. Old, Robert M. Burk
  • THERAPEUTIC AGENTS FOR OCULAR HYPERTENSION
    Publication number: 20120015978
    Abstract: This invention provides well defined 6-alkyl or hydroxyalkyl-1-naphthamide or quinoline compounds for treating glaucoma or ocular hypertension.
    Type: Application
    Filed: June 27, 2011
    Publication date: January 19, 2012
    Applicant: ALLERGAN, INC.
    Inventor: David W. Old
  • Therapeutic N-aryl or N-heteroaryl pyrazolidine and pyrazolidinone derivatives
    Patent number: 8093282
    Abstract: Compounds comprising or a pharmaceutically acceptable salt or a prodrug thereof, are disclosed, wherein J1, U1, U2, B, Y, and A are as described. Methods, compositions, and medicaments related thereto are also disclosed.
    Type: Grant
    Filed: May 1, 2009
    Date of Patent: January 10, 2012
    Assignee: Allergan, Inc.
    Inventors: David W. Old, Danny T. Dinh
  • Therapeutic beta-lactams
    Patent number: 8063033
    Abstract: Compounds comprising or a pharmaceutically acceptable salt or a prodrug thereof, are disclosed, wherein Y is A is —(CH2)6—, cis —CH2CH?CH—(CH2)3—, or —CH2C?C—(CH2)3—, wherein 1 or 2 carbon atoms may be substituted with S or O; or A is —(CH2)m—Ar—(CH2)o— wherein Ar is substituted or unsubstituted phenyl or monocyclic heteroaryl, the sum of m and o is from 1 to 4, and wherein one CH2 may be replaced with S or O; X is S or O; R is a hydrocarbyl or a hydroxyhydrocarbyl moiety having from 1 to 12 carbon atoms; D is independently a moiety comprising from 1 to 6 non-hydrogen atoms; and n is an integer from 0 to 4. Methods, compositions, and medicaments related thereto are also disclosed.
    Type: Grant
    Filed: January 13, 2009
    Date of Patent: November 22, 2011
    Assignee: Allergan, Inc.
    Inventors: David W. Old, Danny T. Dinh, Robert M. Burk
  • SUBSTITUTED GAMMA LACTAMS AS THERAPEUTIC AGENTS
    Publication number: 20110275692
    Abstract: A compound comprising or a pharmaceutically acceptable salt, prodrug, or a metabolite thereof is disclosed herein. Y, A, and B are as described herein. Methods, compositions, and medicaments related to these compounds are also disclosed.
    Type: Application
    Filed: May 27, 2011
    Publication date: November 10, 2011
    Applicant: ALLERGAN, INC.
    Inventors: David W. Old, Danny T. Dinh
  • Therapeutic compounds
    Patent number: 8044092
    Abstract: A compound having a substituted five or six-membered carbocycle or heterocycle directly bonded to a substituted aryl or heteroaryl ring, wherein said compound has an EC50 value of 20 nM or less at the prostaglandin EP2 receptor according to the cAMP assay. Methods, compositions, and medicaments related thereto are also disclosed.
    Type: Grant
    Filed: August 20, 2010
    Date of Patent: October 25, 2011
    Assignee: Allergan, Inc.
    Inventors: Yariv Donde, Robert M. Burk, David W. Old
  • Therapeutic substituted gamma lactams
    Patent number: 8039507
    Abstract: Disclosed herein is a compound having a structure or a pharmaceutically acceptable salt or a prodrug thereof; wherein Y, A, X, R and D are as described. Methods, compositions, and medicaments related thereto are also disclosed.
    Type: Grant
    Filed: June 6, 2006
    Date of Patent: October 18, 2011
    Assignee: Allergan, Inc.
    Inventor: David W. Old
  • Therapeutic compounds
    Patent number: 8039496
    Abstract: Disclosed herein is a compound of the formula. Therapeutic methods, compositions, and medicaments for the treatment of glaucoma or ocular hypertension related thereto are also disclosed.
    Type: Grant
    Filed: January 22, 2008
    Date of Patent: October 18, 2011
    Assignee: Allergan, Inc.
    Inventors: David W. Old, Vinh X. Ngo
  • Therapeutic compounds
    Patent number: 8003680
    Abstract: Disclosed herein are compounds of the formula therapeutic methods, compositions, and medicaments related thereto are also disclosed.
    Type: Grant
    Filed: September 8, 2009
    Date of Patent: August 23, 2011
    Assignee: Allergan, Inc.
    Inventors: David W. Old, Vinh X. Ngo
  • Therapeutic substituted thiazolidinones, oxazolidinones, and related compounds
    Patent number: 8003678
    Abstract: A compound having a structure is disclosed herein. Therapeutic methods, compositions, and medicaments related thereto are also disclosed.
    Type: Grant
    Filed: December 15, 2009
    Date of Patent: August 23, 2011
    Assignee: Allergan, Inc.
    Inventor: David W. Old
  • Therapeutic substituted lactams
    Patent number: 7998998
    Abstract: Disclosed herein are compounds having a formula: (I) Compositions, methods, and medicaments related thereto are also disclosed.
    Type: Grant
    Filed: October 16, 2008
    Date of Patent: August 16, 2011
    Assignee: Allergan, Inc.
    Inventors: David W. Old, Vinh X. Ngo