Abstract: Aspects of this disclosure provide compositions, strategies, systems, reagents, methods, and kits that are useful for the targeted editing of nucleic acids, including editing a single site within the genome of a cell or subject, e.g., within the human genome. Fusion proteins capable of inducing a cytosine (C) to guanine (G) change (i.e., transversion changes) in a nucleic acid (e.g., genomic DNA) are provided. Fusion proteins of a nucleic acid programmable DNA binding protein (e.g., Cas9) and nucleic acid editing proteins or protein domains, e.g., deaminase domains, polymerase domains, base excision enzymes, and/or DNA repair proteins, are also provided. Methods for targeted nucleic acid editing are also provided. Reagents and kits for the generation of targeted nucleic acid editing proteins, e.g., fusion proteins of a nucleic acid programmable DNA binding protein (e.g., Cas9), and nucleic acid editing proteins or domains, are further provided in the present disclosure.

Abstract: A method and apparatus for automatically switching the resolution of an image stored in a memory when the memory can no longer store another image with the present resolution. A processor first determines the amount of available memory in the memory for storing image data. The resolution is then automatically switched from a high resolution to a low resolution when available memory is above a first predetermined level and below a second predetermined level.

Abstract: A special purpose modular receptacle comprises a generally rectangular housing having an opening which exposes a cavity within the housing. A plurality of electrical contacts are disposed within the cavity of the housing. Terminal ends of the contacts electrically connect to corresponding contacts on a standard modular connector or a modified modular connector inserted into the cavity. The contacts are exposed at a lower rear portion of the housing allowing connection between the contacts and a printed circuit board. Attachment means allow physical and electrical connection of the housing to a printed circuit board. A guiding means may be present as a modular connector insertion aid.

Abstract: A special purpose modular connector comprising a generally rectangular housing having a central body portion and two extending side arm portions. A plurality of electrical contacts are disposed within the body and arm portions. Slots at a front end of each portion of the housing expose a terminal end of each electrical contact. Openings in the rear portions of the housing allow connection of cables or other types of component wiring to the contacts. A locking tab is formed at the underside of the housing and functions to align and securely connect the special purpose modular connector with a correspondingly modified receptacle.