Patents by Inventor David Waddington

David Waddington has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Systems and methods for susceptibility contrast imaging of nanoparticles at low magnetic fields
    Patent number: 11835610
    Abstract: Systems and methods are provided for susceptibility contrast imaging of nanoparticles at low magnetic fields. A susceptibility-based MRI technique, such as imaging with a balanced steady-state free precession (bSSFP) pulse sequence, may be used for imaging a contrast agent such as biocompatible superparamagnetic nanoparticles at ultra-low fields. The contrast agent and imaging technique may be used to improving the visibility of anatomical structures and detecting diseases, such as cancer, with low-field MRI.
    Type: Grant
    Filed: July 15, 2022
    Date of Patent: December 5, 2023
    Assignee: The General Hospital Corporation
    Inventors: Matthew S. Rosen, Zdenka Kuncic, David Waddington
  • SYSTEMS AND METHODS FOR SUSCEPTIBILITY CONTRAST IMAGING OF NANOPARTICLES AT LOW MAGNETIC FIELDS
    Publication number: 20230029685
    Abstract: Systems and methods are provided for susceptibility contrast imaging of nanoparticles at low magnetic fields. A susceptibility-based MRI technique, such as imaging with a balanced steady-state free precession (bSSFP) pulse sequence, may be used for imaging a contrast agent such as biocompatible superparamagnetic nanoparticles at ultra-low fields. The contrast agent and imaging technique may be used to improving the visibility of anatomical structures and detecting diseases, such as cancer, with low-field MRI.
    Type: Application
    Filed: July 15, 2022
    Publication date: February 2, 2023
    Inventors: Matthew S. Rosen, Zdenka Kuncic, David Waddington
  • DENSITY FLOW METER FOR PHARMACEUTICAL FORMULATION DOSING
    Publication number: 20220071847
    Abstract: Provided are systems and method for dosing a pharmaceutical formulation. These methods and systems can displace the pharmaceutical formulation through a density flow meter, wherein the density flow meter is configured to measure a density of the pharmaceutical formulation. Next, the pharmaceutical formulation can be dosed into preformed molds and the dosing process can be stopped when the density of the pharmaceutical formulation measured by the density flow meter is below a predetermined threshold.
    Type: Application
    Filed: November 18, 2021
    Publication date: March 10, 2022
    Applicant: Catalent U.K. Swindon Zydis Limited
    Inventors: David WADDINGTON, Matthew WORT, Katherine ARNEIL
  • Density flow meter for pharmaceutical formulation dosing
    Patent number: 11185470
    Abstract: Provided are systems and method for dosing a pharmaceutical formulation. These methods and systems can displace the pharmaceutical formulation through a density flow meter, wherein the density flow meter is configured to measure a density of the pharmaceutical formulation. Next, the pharmaceutical formulation can be dosed into preformed molds and the dosing process can be stopped when the density of the pharmaceutical formulation measured by the density flow meter is below a predetermined threshold.
    Type: Grant
    Filed: July 30, 2020
    Date of Patent: November 30, 2021
    Assignee: Catalent U.K. Swindon Zydis Limited
    Inventors: David Waddington, Matthew Wort, Katherine Arneil
  • DENSITY FLOW METER FOR PHARMACEUTICAL FORMULATION DOSING
    Publication number: 20210030623
    Abstract: Provided are systems and method for dosing a pharmaceutical formulation. These methods and systems can displace the pharmaceutical formulation through a density flow meter, wherein the density flow meter is configured to measure a density of the pharmaceutical formulation. Next, the pharmaceutical formulation can be dosed into preformed molds and the dosing process can be stopped when the density of the pharmaceutical formulation measured by the density flow meter is below a predetermined threshold.
    Type: Application
    Filed: July 30, 2020
    Publication date: February 4, 2021
    Applicant: Catalent U.K. Swindon Zydis Limited
    Inventors: David WADDINGTON, Matthew WORT, Katherine ARNEIL
  • SYSTEM AND METHOD FOR IMAGING NANODIAMONDS AS DYNAMIC NUCLEAR POLARIZATION AGENT
    Publication number: 20180113185
    Abstract: A system and method performing a medical imaging process includes arranging a subject to receive solution comprising nanodiamonds, performing an MRI imaging process to acquire data from the subject, and reconstructing the data to generate a report indicating a spatial distribution of nanodiamonds in the subject.
    Type: Application
    Filed: April 1, 2016
    Publication date: April 26, 2018
    Inventors: Matthew S. Rosen, Mathieu Sarracanie, Huiliang Zhang, David Riley, Ronald L. Walsworth, David Waddington