Abstract: Administering a business transaction, including: receiving a request for a business transaction, the request containing data to be processed by the business transaction and metadata describing the data and the request; creating, in dependence upon classification rules, the data to be processed by the business transaction, and the metadata describing the data and the request, a business object representing the business transaction; selecting, in dependence upon workflow selection rules and attributes of the business object, one or more workflows to process the data to be processed by the business transaction; processing the data to be processed by the business transaction with the workflows, thereby creating a resultant business object and resultant data; and routing, in dependence upon content routing rules and the attributes of the resultant business object, the resultant data to a destination.

Abstract: Techniques are provided for accessing data within data repositories. Public UDTFs, private UDTFs and a metadata processor are utilized to provide access to data residing in a variety of data repositories.

Abstract: Methods, systems and articles of manufacture are provided for accessing data within data repositories. Public UDTFs, private UDTFs and a metadata processor are utilized to provide access to data residing in a variety of data repositories.

Abstract: Administering medical digital images including receiving a medical image business object representing a transaction carrying out a type of service request made by a health care provider; selecting, in dependence upon workflow selection rules and the attributes of the medical image business object, one or more clinical workflows to process the medical image according to the transaction; and processing the medical image of the request with the clinical workflows, thereby creating a resultant business object and resultant medical image including selecting, by the workflow dispatcher in dependence upon metadata for computational units in the distributed medical digital image computing environment, particular computational units in the distributed medical digital image computing environment to perform particular services of the one or more clinical workflows, deploying the particular services to the particular computational units, and executing the services on the computational units upon which they are deployed.

Abstract: Administering medical digital images including receiving a request for an image processing transaction to process the medical digital image; storing the medical image in one or more medical image caches; creating a medical image business object representing the business transaction; storing the medical image business object in the medical image metadata database; selecting, in dependence upon workflow selection rules and the attributes of the medical image business object, one or more clinical workflows to process the medical image; processing the medical image of the request with the clinical workflows, thereby creating a resultant business object and resultant medical image; routing the resultant medical image to a destination.

Abstract: Administering medical digital images including receiving a request for an image processing transaction to process the medical digital image; creating a medical image business object representing the business transaction; storing the medical image business object in the medical image metadata database; storing the medical image in the medical image repository; selecting, in dependence upon workflow selection rules and the attributes of the medical image business object, one or more clinical workflows to process the medical image; processing the medical image of the request with the clinical workflows, thereby creating a resultant business object and resultant medical image; routing the resultant medical image to a destination.

Abstract: The present invention generally provides methods, systems, and articles of manufacture for managing an annotation system that includes storing annotations for a document family, i.e., a series of versions of a data source. Annotations created for one version of the data source may be viewed in context from both subsequent and prior versions of the same data source. Embodiments of the invention associate annotations with both a data source “family identifier” as well as a “version identifier.” Other than adding a family ID to the data source, the data source remains unchanged. The family ID is maintained across different versions of the data source, whereas version IDs are determined for a specific version of the data source. Version IDs can be constructed from each data source directly, and do not need to be stored.

Abstract: The present invention relates to novel oxadiazole derivatives having pharmacological activity, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders.

Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof: wherein A is hydrogen, C1-4alkyl, C3-6cycloalkyl, C1-3alkoxy, C1-3alkoxy C1-4alkyl, C1-2fluoroalkyl, halogen, NR6R7, optionally substituted heteroaryl, or optionally substituted phenyl, and R1, R2, R3, R4, R5, R6 and R7 are as defined in the description. The compounds or salts are thought to modulate P2X7 receptor function and to be capable of antagonizing the effects of ATP at the P2X7 receptor. The invention also provides the use of the compound or salt in the treatment or prophylaxis of, for example, inflammatory pain, neuropathic pain, visceral pain, rheumatoid arthritis or osteoarthritis or neurodegenerative disorders.

Abstract: A trace gas sensing apparatus includes a cathode, an anode, a vacuum enclosure, and a membrane. The anode coaxially surrounds the cathode, wherein the cathode and the anode define an annular ionization chamber. The vacuum enclosure surrounds the cathode and the anode and includes a gas inlet fluidly communicating with the ionization chamber. The membrane is coupled to the gas inlet in a sealed manner and is permselective to trace gas. The apparatus may further include circuitry for applying a negative voltage potential to the cathode and for measuring an ion current signal generated by the cathode, and a magnet assembly for generating a magnetic field in the ionization chamber. The cathode may include an elongated member located along a longitudinal axis, and first and second end plates orthogonal to the longitudinal axis.

Abstract: The availability of one or more databases targeted by a federated query may be determined prior to running the federated query against the targeted databases. In response to determining one or more of the targeted databases are unavailable, a user may be notified. The user may also be presented with options for running the federated query. The options may include being notified when all of the targeted databases are available, automatically running the federated query (in the background) when all of the targeted databases are available, and modifying the query to run against currently available databases.

Abstract: The present invention relates to novel oxadiazole derivatives having pharmacological activity, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders.

Abstract: The present invention relates to novel oxadiazole derivatives having pharmacological activity, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders.

Abstract: The present invention relates to novel oxadiazole derivatives having pharmacological activity, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders.

Abstract: The present invention relates to novel pyrimidine derivatives such as compounds of the formula (I): and the use of such compounds or pharmaceutical compositions thereof in the treatment of diseases, particularly pain, which are mediated by the activity of the cannabinoid 2 receptor.

Abstract: Methods, systems, and articles of manufacture for proving global annotation services are disclosed. Global annotations are used to annotate a data element independently from the internal representation of a data element employed by a particular software application. Data elements are normalized into a form used by a global annotation system to identify the data element, and corresponding global annotations, independent from the application in which the data element may appear. An annotation cache may be used to store the global annotations that have been created for a particular data source, improving the efficiency of the global annotation system.

Abstract: An improved method, system, and article of manufacture for issuing a query against multiple data sources that may not each contain all the fields involved in the query is provided. A diverse query targeting the multiple data sources may be decomposed into individual query predicates. For each data source, an effective query may be generated by removing, from the diverse query, individual predicates involving fields not contained in the data source. Partial results received in response to issuing the effective queries against their corresponding data sources may be merged using any suitable technique.

Abstract: The present invention relates to novel pyridine derivatives such as compounds of the formula (I): and the use of such compounds or pharmaceutical compositions thereof in the treatment of diseases, particularly pain, which are mediated by the activity of the cannabinoid 2 receptor.

Abstract: The present invention generally provides methods, systems, and articles of manufacture for managing an annotation system that includes storing annotations for a document family, i.e., a series of versions of a data source. Annotations created for one version of the data source may be viewed in context from both subsequent and prior versions of the same data source. Embodiments of the invention associate annotations with both a data source “family identifier” as well as a “version identifier.” Other than adding a family ID to the data source, the data source remains unchanged. The family ID is maintained across different versions of the data source, whereas version IDs are determined for a specific version of the data source. Version IDs can be constructed from each data source directly, and do not need to be stored.

Abstract: Embodiments of the present invention generally provide a system, method and article of manufacture for managing federated queries. In general, the availability of one or more databases targeted by a federated query may be determined prior to running the federated query against the targeted databases. In response to determining one or more of the targeted databases are unavailable, a user may be notified. The user may also be presented with options for running the federated query. The options may include being notified when all of the targeted databases are available, automatically running the federated query (in the background) when all of the targeted databases are available, and modifying the query to run against currently available databases.