Patents by Inventor David Wallach

David Wallach has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240346910
    Abstract: Example implementations include a method, apparatus, and computer-readable medium comprising receiving, by a short range communication radio in a control panel, a short range communication signal transmitted by a device; determining, by the control panel, whether the device is a known device; and automatically disarming the control panel responsive to recognizing the device as the known device.
    Type: Application
    Filed: June 25, 2024
    Publication date: October 17, 2024
    Inventors: Walter WALLACH, Anand SASTRY, David PULLING
  • Patent number: 12046121
    Abstract: Example implementations include a method, apparatus, and computer-readable medium comprising receiving, by a short range communication radio in a control panel, a short range communication signal transmitted by a device; determining, by the control panel, whether the device is a known device; and automatically disarming the control panel responsive to recognizing the device as the known device.
    Type: Grant
    Filed: August 25, 2021
    Date of Patent: July 23, 2024
    Assignee: Johnson Controls Tyco IP Holdings LLP
    Inventors: Walter Wallach, Anand Sastry, David Pulling
  • Publication number: 20190195891
    Abstract: A method of detecting activation of a necroptosis activation pathway in a subject is disclosed. The method comprising: (a) obtaining a biological sample comprising exosomes from the subject; (b) detecting an activity or expression of a component of the necroptosis activation pathway in an exosome fraction of the biological sample, wherein an increase in the activity or expression of the component of the necroptosis activation pathway indicates the activation of said necroptosis activation pathway. Methods of diagnosing necroptosis or inflammation by determining the level of exosomes in a biological sample. Method of modulating endocytosis by inhibiting MLKL or a cell surface receptor and a pharmaceutical composition comprising a population of exosomes comprising a component of the necroptosis activation pathway and its use in therapy of diseases, such as inflammation and cancer.
    Type: Application
    Filed: August 18, 2017
    Publication date: June 27, 2019
    Applicant: Yeda Research and Development Co. Ltd.
    Inventors: David WALLACH, Andrew KOVALENKO, Seongmin YOON
  • Patent number: 9270780
    Abstract: An apparatus, system and method of providing a latent celebration of memorable events, or a recurring celebration of an event in a timely manner, which allows for a determination of a latency or recurring period, whereupon remembrances, such as photos, may be shared amongst the celebrants.
    Type: Grant
    Filed: April 23, 2014
    Date of Patent: February 23, 2016
    Inventors: Kenneth David Wallach, Benjamin Scott Klein
  • Publication number: 20150329867
    Abstract: The invention relates to the treatment or prevention of an inflammatory skin disease, disorder or condition, by modulating a protein that is normally regulated by caspase-8 in the skin or by increasing caspase-8 activity or level in the skin. Another aspect of the invention relates to methods for diagnosing an inflammatory skin disease, disorder or condition or a predisposition to develop said disease disorder or condition in an individual. Further aspects of the invention relate to methods for identifying target proteins involved in the course or pathology of an inflammatory skin disease, disorder or condition and to methods of screening a candidate compound for treating said disease, disorder or condition. In particular, the invention relates to inflammatory skin diseases such as atopic dermatitis and psoriasis.
    Type: Application
    Filed: July 2, 2015
    Publication date: November 19, 2015
    Inventors: David WALLACH, Andrei KOVALENKO, Tae-Bong KANG, Jin Chul KIM
  • Publication number: 20140317192
    Abstract: An apparatus, system and method of providing a latent celebration of memorable events, or a recurring celebration of an event in a timely manner, which allows for a determination of a latency or recurring period, whereupon remembrances, such as photos, may be shared amongst the celebrants.
    Type: Application
    Filed: April 23, 2014
    Publication date: October 23, 2014
    Inventors: Kenneth David Wallach, Benjamin Scott Klein
  • Patent number: 8383781
    Abstract: An antibody or antibody preparation being capable of specifically binding the amino acid sequence of NF-&kgr; B-inducing kinase (NIK) MAP3K14, or a specific portion thereof, and of thereby regulating a biochemical activity of NIK, and/or enabling detection of NIK or a specific portion thereof.
    Type: Grant
    Filed: October 5, 2004
    Date of Patent: February 26, 2013
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: David Wallach, Parameswaran Ramakrishnan
  • Patent number: 8377433
    Abstract: The present invention relates to a splice variant of SIVA, SIVA3, and to its use.
    Type: Grant
    Filed: February 9, 2009
    Date of Patent: February 19, 2013
    Assignee: Yeda Research and Development Co., Inc., Weizmann Institute of Science.
    Inventors: David Wallach, Parameswaran Ramakrishnan, Andrei Kovalenko
  • Patent number: 8362206
    Abstract: The present invention provides a chimeric protein capable of killing or modifying a cell expressing abnormally high levels of a ligand of a receptor of the TNF/NGF family, comprising the amino acid sequence of at least one polypeptide consisting of an extracellular portion of said receptor connected to an effector molecule. In addition the invention provides pharmaceutical compositions comprising said chimeric protein and use thereof.
    Type: Grant
    Filed: June 28, 2005
    Date of Patent: January 29, 2013
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: David Wallach, Elena Appel, Tanya Goncahrov
  • Patent number: 8338567
    Abstract: A method of treating a disease associated with NF-?B activity. The method is effected by providing to a subject in need thereof a therapeutically effective amount of an agent capable of modulating NIK-HC8 binding.
    Type: Grant
    Filed: December 11, 2005
    Date of Patent: December 25, 2012
    Assignee: Yeda Research and Development Co., Ltd.
    Inventors: David Wallach, Parameswaran Makrishnan, Taisa Shmushkovich
  • Patent number: 8330026
    Abstract: The invention relates to the use of NF-?B inducing kinase (NIK) and related molecules for the modulation of signal activities controlled by cytokines, and some new such molecules.
    Type: Grant
    Filed: April 15, 2003
    Date of Patent: December 11, 2012
    Assignee: Yeda Research and Development Co., Ltd., Weizmann Institute of Science
    Inventors: David Wallach, Parameswaran Ramakrishnan, Taisia Shmushkovich
  • Patent number: 8318660
    Abstract: The invention relates to caspases and to extracellular use of caspases for regulating cell functions.
    Type: Grant
    Filed: March 5, 2007
    Date of Patent: November 27, 2012
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: David Wallach, Elena Appel, Andrei Kovalenko, Rajput Akhill
  • Patent number: 8304384
    Abstract: The present invention relates to the regulatory role of caspase-8 in infection by intracellular pathogen, inflammation and wound healing.
    Type: Grant
    Filed: June 27, 2007
    Date of Patent: November 6, 2012
    Assignees: Yeda Research and Development Co., Ltd, Hadasit Medical Research Services and Development Ltd.
    Inventors: David Wallach, Rinat Abramovitch, Eitan Galun, Tehila Ben Moshe, Hila Barash
  • Patent number: 8273545
    Abstract: The present invention relates to the ubiquitination and/or degradation-related activity of a SIVA polypeptide and to agents capable of modulating said activity.
    Type: Grant
    Filed: January 11, 2007
    Date of Patent: September 25, 2012
    Assignees: Yeda Research and Development Co. Ltd, Weizmann Institute of Science
    Inventors: David Wallach, Parameswaran Ramakrishnan, Wang Wangxia, Andrei Kovalenko
  • Patent number: 8236507
    Abstract: A DNA sequence encoding a protein capable of binding to a tumor necrosis factor receptor-associated factor (TRAF) molecule, TRAF-binding proteins, their isoforms, analogs, fragments and derivatives encoded by the DNA sequence, their methods for the production of the DNA sequences and proteins, and the uses for the DNA sequence and proteins.
    Type: Grant
    Filed: February 3, 2009
    Date of Patent: August 7, 2012
    Assignee: Yeda Research and Development Co., Ltd.
    Inventors: David Wallach, Nikolai Malinin, Mark Boldin, Andrei Kovalenko, Igor Mett
  • Publication number: 20120144504
    Abstract: The invention relates to the treatment or prevention of an inflammatory skin disease, disorder or condition, by modulating a protein that is normally regulated by caspase-8 in the skin or by increasing caspase-8 activity or level in the skin. Another aspect of the invention relates to methods for diagnosing an inflammatory skin disease, disorder or condition or a predisposition to develop said disease disorder or condition in an individual. Further aspects of the invention relate to methods for identifying target proteins involved in the course or pathology of an inflammatory skin disease, disorder or condition and to methods of screening a candidate compound for treating said disease, disorder or condition. In particular, the invention relates to inflammatory skin diseases such as atopic dermatitis and psoriasis.
    Type: Application
    Filed: October 16, 2006
    Publication date: June 7, 2012
    Applicant: Yeda Research and Development Co. Ltd.
    Inventors: David Wallach, Andrei Kovalenko, Tae-Bong Kang, Jin Chul Kim
  • Patent number: 8138323
    Abstract: An isolated DNA molecule has the sequence of encoding a fragment of encoding Tumor Necrosis Factor (TNF) Binding Protein II. It has a length sufficient to serve as an immunogen for raising antibodies against a polypeptide that is a fragment of TNF Binding Protein II. The DNA may be used to produce replicable expression vehicles and prokaryotic or eukaryotic expression host cells. Such host cells may be used to produce polypeptides encoded by such DNA molecules.
    Type: Grant
    Filed: December 16, 2002
    Date of Patent: March 20, 2012
    Assignee: Yeda Research and Development Co., Ltd.
    Inventors: David Wallach, Hartmut Engelmann, Dan Aderka, Daniela Novick, Menachem Rubinstein
  • Patent number: 8092806
    Abstract: The present invention relates to a chimeric protein comprising a cell-targeting agent and a Yersinia outer protein, connected by a translocating polypeptide. The invention further relates to the preparation and use of such chimeric protein.
    Type: Grant
    Filed: April 10, 2006
    Date of Patent: January 10, 2012
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: David Wallach, Elena Appel
  • Publication number: 20110293593
    Abstract: The present invention relates to modulation of SIVA2 stability by N-acetylglucosamine, phosphorylation of ubiquitination in treatment or prevention of diseases, disorders or conditions.
    Type: Application
    Filed: February 11, 2009
    Publication date: December 1, 2011
    Applicant: YEDA RESEARCH AND DEVELOPMENT CO., LTD.
    Inventors: David Wallach, Parameswaran Ramakrishnan, Andrei Kovalenko
  • Patent number: 8048847
    Abstract: This invention relates to the use of the IL-2 common gamma (c?c) and related molecules for the modulation of signal activities controlled by NIK, and some new such molecules.
    Type: Grant
    Filed: July 1, 2008
    Date of Patent: November 1, 2011
    Assignee: Yeda Research and Development Co., Ltd.
    Inventors: David Wallach, Parameswaran Ramakrishnan, Taisia Shmushkovich