Patents by Inventor David Waterman
David Waterman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240011007Abstract: Provided herein are compositions and methods of using prime editing systems comprising prime editors and prime editing guide RNAs for treatment of genetic disorders.Type: ApplicationFiled: August 14, 2023Publication date: January 11, 2024Inventors: Jennifer Gori, David Waterman, Jack Heath, Andrew V. Anzalone
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Publication number: 20230311118Abstract: A microfluidic device comprises: a sensor provided in a sensing chamber; a liquid inlet and liquid outlet connecting to the sensor chamber for respectively passing liquid into and out of the sensing chamber and; a sample input port in fluid communication with the liquid inlet; a liquid collection channel downstream of the sensing chamber outlet; a flow path interruption between the liquid outlet and the liquid collection channel, preventing liquid from flowing into the liquid collection channel from upstream; a buffer liquid filling from the sample input port to the sensing chamber, and filling the sensing chamber and filing from the liquid outlet to the flow path interruption; an activation system operable to complete the flow path between the liquid outlet and the liquid collection channel such that the sensor remains unexposed to gas or a gas/liquid interface.Type: ApplicationFiled: January 31, 2023Publication date: October 5, 2023Applicant: Oxford Nanopore Technologies PLCInventor: David Waterman
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Patent number: 11596940Abstract: A microfluidic device comprises: a sensor provided in a sensing chamber; a liquid inlet and liquid outlet connecting to the sensor chamber for respectively passing liquid into and out of the sensing chamber and; a sample input port in fluid communication with the liquid inlet; a liquid collection channel downstream of the sensing chamber outlet; a flow path interruption between the liquid outlet and the liquid collection channel, preventing liquid from flowing into the liquid collection channel from upstream; a buffer liquid filling from the sample input port to the sensing chamber, and filling the sensing chamber and filing from the liquid outlet to the flow path interruption; an activation system operable to complete the flow path between the liquid outlet and the liquid collection channel such that the sensor remains unexposed to gas or a gas/liquid interface.Type: GrantFiled: July 6, 2017Date of Patent: March 7, 2023Assignee: Oxford Nanopore Technologies PLCInventor: David Waterman
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Publication number: 20210300750Abstract: A component (8) adapted to engage with a receiver (6) has an array of contact pads (16) to removeably connect with a corresponding array of connectors (18) on the receiver (6). Each contact pad (16) of the array is electrically connected to the electrode (26) of a corresponding recess or well (28) that is part of a sensor, wherein a membrane is formable across each recess. A conductive grid (102) is configured between the contact pads (16) of the array, to inhibit an electrostatic discharge (ESD) conducting across the recesses or wells and/or direct an ESD away from the recesses or wells.Type: ApplicationFiled: May 8, 2019Publication date: September 30, 2021Inventor: David WATERMAN
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Publication number: 20210170403Abstract: A microfluidic device for analysing a test liquid comprises: a sensor (235), such as a membrane provided with nanopores, provided in a sensing chamber (237); a sensing chamber inlet channel (261) and a sensing chamber outlet channel (262), each connecting to the sensing chamber for respectively passing liquid into and out of the sensing chamber, and a reservoir (233) forming a sample input port to the microfluidic device, the reservoir being in fluid communication with the sensing chamber inlet channel (261); a liquid collection channel (232); a barrier (231) between an end of the sensing chamber outlet channel (262) and the liquid collection channel (232); a first seal (251), covering the sample input port; a second seal (252), covering the end of the sensing chamber outlet channel (262), thereby preventing liquid from flowing from the sensing chamber (237), over the barrier (231), into the liquid collection channel (232); wherein the microfluidic device is filled with a liquid from the first seal (251) at tType: ApplicationFiled: November 23, 2018Publication date: June 10, 2021Applicant: Oxford Nanopore Technologies LimitedInventor: David Waterman
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Patent number: 11024998Abstract: A kit which has a first and second component parts, which are adapted for connection with each other. The first component part has a first array of electrical sensors, two substantially parallel lateral walls on the sides of the electrical connectors, two rails extending along the sides of the array, a front contact point and an overhang for receiving the second part. The second component part has a second array of electrical sensors for connection to the first array, front end configured to fit between the lateral walls of the first connector, and lateral sides having rail reliefs to fit the rails of the first connector. Connection of the first component part and the second component part forms a shoulder that aligns to locate the second array of electrical connectors in correct position for connection to the first array of electrical connectors.Type: GrantFiled: September 28, 2017Date of Patent: June 1, 2021Assignee: Oxford Nanopore Technologies Ltd.Inventors: David Waterman, Richard Smith
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Publication number: 20200266568Abstract: A kit comprising first and second component parts adapted for connection to each other, wherein: the first component part comprises: a first array of electrical connectors; two substantially parallel lateral walls, one provided on either side of the first array of electrical connectors at a predetermined position with respect to the first array of electrical connectors; two rails provided between the first array of electrical connectors and the lateral walls, one rail being on either side of the first array of electrical connectors, wherein each rails extends at least along a length of the first array of electrical connectors, and has a front tip positioned at a predetermined position with respect to the first array of electrical connectors; a front contact point; an overhang for receiving the second component; the second component part comprises: a second array of electrical connectors, for connection to the first array of electrical connectors; a front end being configured to fit to a width between the paraType: ApplicationFiled: September 28, 2017Publication date: August 20, 2020Applicant: Oxford Nanopore Technologies LimitedInventors: David Waterman, Richard Smith
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Publication number: 20190210021Abstract: A microfluidic device comprises: a sensor provided in a sensing chamber; a liquid inlet and liquid outlet connecting to the sensor chamber for respectively passing liquid into and out of the sensing chamber and; a sample input port in fluid communication with the liquid inlet; a liquid collection channel downstream of the sensing chamber outlet; a flow path interruption between the liquid outlet and the liquid collection channel, preventing liquid from flowing into the liquid collection channel from upstream; a buffer liquid filling from the sample input port to the sensing chamber, and filling the sensing chamber and filing from the liquid outlet to the flow path interruption; an activation system operable to complete the flow path between the liquid outlet and the liquid collection channel such that the sensor remains unexposed to gas or a gas/liquid interface.Type: ApplicationFiled: July 6, 2017Publication date: July 11, 2019Applicant: Oxford Nanopore Technologies Ltd.Inventor: David Waterman
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Patent number: 8540172Abstract: A sachet (1) having walls of flexible material is disclosed. The walls are joined so as to form an impermeable seal, thereby defining a cavity within the sachet (1). A conduit (2) passing through the seal and having inner and outer ends is disposed with the inner end within the cavity and the outer end outside the sachet (1) such that the cavity is in fluid communication, via the conduit, with the outside of the sachet. The cavity contains a volume of liquid (8) in use, and the conduit (2) is adapted to prevent the liquid (8) flowing from the cavity without the application of an additional stimulus, irrespective of the orientation of the sachet (1).Type: GrantFiled: July 28, 2005Date of Patent: September 24, 2013Assignee: Atrium Innovation, LimitedInventors: David Waterman, Alastair Pirrie
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Patent number: 8448819Abstract: A dispenser system comprising a reservoir, a closure device for controlling the flow of liquid from the reservoir, and a housing to which the reservoir is attached is disclosed. The reservoir is movable relative to the housing from a storage position in which the closure device prevents liquid flowing from the reservoir to a dispensing position in which the closure device allows liquid to flow from the reservoir. The housing comprises an activation device which on movement of the reservoir from the storage position to the dispensing position causes the closure device to allow the liquid to flow from the reservoir.Type: GrantFiled: January 17, 2006Date of Patent: May 28, 2013Assignee: Atrium Innovation LimitedInventors: Alastair Bruce Pirrie, David Waterman
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Patent number: D643024Type: GrantFiled: February 18, 2011Date of Patent: August 9, 2011Assignee: Samson Technologies Corp.Inventors: Scott Goodman, Min Yang, Douglas Bryant, David Waterman
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Patent number: D891400Type: GrantFiled: August 27, 2018Date of Patent: July 28, 2020Assignee: ZIGBEE PTY LTD.Inventors: David Waterman, Taisen Maddern, Scott Pringle
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Patent number: D892081Type: GrantFiled: September 6, 2018Date of Patent: August 4, 2020Assignee: ZIGBEE PTY LTD.Inventors: David Waterman, Taisen Maddern, Scott Pringle
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Patent number: D906287Type: GrantFiled: September 6, 2018Date of Patent: December 29, 2020Assignee: Zigbee PTY LTD.Inventors: David Waterman, Taisen Maddern, Scott Pringle
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Patent number: D910196Type: GrantFiled: May 9, 2019Date of Patent: February 9, 2021Assignee: Oxford Nanopore Technologies Ltd.Inventor: David Waterman
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Patent number: D910197Type: GrantFiled: May 9, 2019Date of Patent: February 9, 2021Assignee: Oxford Nanopore Technologies Ltd.Inventor: David Waterman
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Patent number: D911545Type: GrantFiled: May 9, 2019Date of Patent: February 23, 2021Assignee: Oxford Nanopore Technologies Ltd.Inventor: David Waterman
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Patent number: D933892Type: GrantFiled: April 20, 2020Date of Patent: October 19, 2021Assignee: EDGEWELL PERSONAL CARE BRANDS, LLCInventors: David Waterman, Ju Byung Hoon
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Patent number: D980526Type: GrantFiled: August 17, 2021Date of Patent: March 7, 2023Assignee: EDGEWELL PERSONAL CARE BRANDS, LLCInventors: David Waterman, Ju Byung Hoon, Tai Hoon Kim
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Patent number: D1023073Type: GrantFiled: February 24, 2023Date of Patent: April 16, 2024Assignee: CQMS Pty LtdInventors: Samuel Beck, Ian Ashby, David Hume, Brendan Waterman, Bruce Lilley, Todd Lawler