Patents by Inventor David Weinstein

David Weinstein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250011291
    Abstract: Compounds and methods for activating Nrf2 by inhibiting KEAP1.
    Type: Application
    Filed: June 13, 2024
    Publication date: January 9, 2025
    Inventors: Karl BEDKE, Jason GREEN, Fabian GOERICKE, Shota KIKUCHI, Donald C. ROGNESS, David WEINSTEIN, Michael WALLACE, Zach OWYANG
  • Patent number: 12187685
    Abstract: Disclosed are compounds of Formula (I): or pharmaceutically acceptable salts or solvates thereof, wherein R1, R3, X, Y, Z, and W are as defined herein. The compounds are, for example, inhibitors of WRN helicase and useful in treating a proliferative disease, such as cancer.
    Type: Grant
    Filed: September 20, 2023
    Date of Patent: January 7, 2025
    Inventors: Shota Kikuchi, Betty Lam, Jason Green, Don Rogness, David Weinstein, Larry Burgess, Benjamin Horning, Kelsey Lamb, Zachary Owyang, Robert Malmstrom
  • Publication number: 20240226114
    Abstract: Compounds and methods for inhibiting Nrf2 by activating KEAP1.
    Type: Application
    Filed: September 28, 2023
    Publication date: July 11, 2024
    Inventors: David WEINSTEIN, Jason GREEN, Shota KIKUCHI, Donald C ROGNESS, Philip ALIBI, Matthew PATRICELLI, Nilotpal ROY, I-Chung LO
  • Publication number: 20240140915
    Abstract: Disclosed are compounds of Formula (I): or pharmaceutically acceptable salts or solvates thereof, wherein R1, R3, X, Y, Z, and W are as defined herein. The compounds are, for example, inhibitors of WRN helicase and useful in treating a proliferative disease, such as cancer.
    Type: Application
    Filed: September 20, 2023
    Publication date: May 2, 2024
    Inventors: Shota Kikuchi, Betty Lam, Jason Green, Don Rogness, David Weinstein, Larry Burgess, Benjamin Horning, Kelsey Lamb, Zachary Owyang, Robert Malmstrom
  • Publication number: 20240067612
    Abstract: Disclosed are compounds of Formula (I): or pharmaceutically acceptable salts or solvates thereof, wherein R1, R3, X, Y, Z, and W are as defined herein. The compounds are, for example, inhibitors of WRN helicase and useful in treating a proliferative disease, such as cancer.
    Type: Application
    Filed: July 5, 2023
    Publication date: February 29, 2024
    Inventors: Shota Kikuchi, Betty Lam, Jason Green, Don Rogness, David Weinstein, Larry Burgess, Benjamin Horning, Kelsey Lamb, Zach Owyang, Robert Malmstrom
  • Publication number: 20240039922
    Abstract: Nextdate provides an online dating and game experience for all participants, including live streamers, contestants, and viewers. Nextdate offers advantages over both offline and online speed dating. In respect to offline speed dating, Nextdate is better in that it provides conversational prompts to the participants (the “star” and the contestant), as well as a “Love-o-meter” and audience comments that provide additional items and context to which the participants can respond. In respect to online speed dating, Nextdate includes features that remove the friction from traditional online dating experience and encourage user participation. Nextdate may be implemented as a standalone app or as a tab or feature of another video-centric social networking app.
    Type: Application
    Filed: October 12, 2023
    Publication date: February 1, 2024
    Inventors: Geoffrey Cook, Anton Djamoos, David Weinstein, Omar Beiruty, Jeremy Zorn
  • Patent number: 11824868
    Abstract: Nextdate provides an online dating and game experience for all participants, including live streamers, contestants, and viewers. Nextdate offers advantages over both offline and online speed dating. In respect to offline speed dating, Nextdate is better in that it provides conversational prompts to the participants (the “star” and the contestant), as well as a “Love-o-meter” and audience comments that provide additional items and context to which the participants can respond. In respect to online speed dating, Nextdate includes features that remove the friction from traditional online dating experience and encourage user participation. Nextdate may be implemented as a standalone app or as a tab or feature of another video-centric social networking app.
    Type: Grant
    Filed: November 16, 2021
    Date of Patent: November 21, 2023
    Assignee: The Meet Group, Inc.
    Inventors: Geoffrey Cook, Anton Djamoos, David Weinstein, Omar Beiruty, Jeremy Zorn
  • Patent number: 11771689
    Abstract: Disclosed herein are compositions and methods for modulating cereblon neosubstrates. A small molecule modulator of Formula (I*), or a pharmaceutically acceptable salt or solvate thereof can be used to modulate cereblon neosubstrates.
    Type: Grant
    Filed: November 17, 2020
    Date of Patent: October 3, 2023
    Assignees: VIVIDION THERAPEUTICS, INC., THE SCRIPPS RESEARCH INSTITUTE
    Inventors: Benjamin F. Cravatt, Matthew Patricelli, Dean Stamos, Gabe Simon, Benjamin Horning, David Weinstein, Ekaterina Vinogradova
  • Publication number: 20220298213
    Abstract: Disclosed herein are in vivo engineered cereblon protein and methods of making the same. The in vivo engineered cereblon protein can include a site-specific non-naturally occurring modification at cysteine 287 as set forth in SEQ ID NO:1, or cysteine 286 as set forth in SEQ ID NO: 2 or 3, the modification comprising a moiety resulting from an in vivo Michael addition reaction between an exogenous Michael acceptor and the cysteine 287 as set forth in SEQ ID NO: 1, or cysteine 286 as set forth in SEQ ID NO: 2 or 3.
    Type: Application
    Filed: May 23, 2022
    Publication date: September 22, 2022
    Inventors: David WEINSTEIN, Benjamin F. CRAVATT, Matthew PATRICELLI, Dean STAMOS, Gabe SIMON, Benjamin HORNING, Ekaterina VINOGRADOVA, Brian NORDIN, Kristen BALTGALVIS, Todd KINSELLA
  • Publication number: 20220224691
    Abstract: Nextdate provides an online dating and game experience for all participants, including live streamers, contestants, and viewers. Nextdate offers advantages over both offline and online speed dating. In respect to offline speed dating, Nextdate is better in that it provides conversational prompts to the participants (the “star” and the contestant), as well as a “Love-o-meter” and audience comments that provide additional items and context to which the participants can respond. In respect to online speed dating, Nextdate includes features that remove the friction from traditional online dating experience and encourage user participation. Nextdate may be implemented as a standalone app or as a tab or feature of another video-centric social networking app.
    Type: Application
    Filed: November 16, 2021
    Publication date: July 14, 2022
    Inventors: Geoffrey Cook, Anton Djamoos, David Weinstein, Omar Beiruty, Jeremy Zorn
  • Publication number: 20220062248
    Abstract: Disclosed herein are compositions and methods for modulating cereblon neosubstrates. A small molecule modulator of Formula (I*), or a pharmaceutically acceptable salt or solvate thereof can be used to modulate cereblon neosubstrates.
    Type: Application
    Filed: November 17, 2020
    Publication date: March 3, 2022
    Inventors: Benjamin F. CRAVATT, Matthew PATRICELLI, Dean STAMOS, Gabe SIMON, Benjamin HORNING, David WEINSTEIN, Ekaterina VINOGRADOVA
  • Patent number: 11178152
    Abstract: Nextdate provides an online dating and game experience for all participants, including live streamers, contestants, and viewers. Nextdate offers advantages over both offline and online speed dating. In respect to offline speed dating, Nextdate is better in that it provides conversational prompts to the participants (the “star” and the contestant), as well as a “Love-o-meter” and audience comments that provide additional items and context to which the participants can respond. In respect to online speed dating, Nextdate includes features that remove the friction from traditional online dating experience and encourage user participation. Nextdate may be implemented as a standalone app or as a tab or feature of another video-centric social networking app.
    Type: Grant
    Filed: September 25, 2019
    Date of Patent: November 16, 2021
    Assignee: The Meet Group, Inc.
    Inventors: Geoffrey Cook, Anton Djamoos, David Weinstein, Omar Beiruty, Jeremy Zorn
  • Publication number: 20210100772
    Abstract: The present invention is directed to a method for simultaneously treating alopecia and achromotrichia comprising topically administering to a human in need thereof an effective amount of a composition comprising a compound of formula (II) or a pharmaceutically acceptable salt or ester thereof, minoxidil and cyclosporine A.
    Type: Application
    Filed: December 17, 2020
    Publication date: April 8, 2021
    Inventor: David Weinstein
  • Publication number: 20210037020
    Abstract: Nextdate provides an online dating and game experience for all participants, including live streamers, contestants, and viewers. Nextdate offers advantages over both offline and online speed dating. In respect to offline speed dating, Nextdate is better in that it provides conversational prompts to the participants (the “star” and the contestant), as well as a “Love-o-meter” and audience comments that provide additional items and context to which the participants can respond. In respect to online speed dating, Nextdate includes features that remove the friction from traditional online dating experience and encourage user participation. Nextdate may be implemented as a standalone app or as a tab or feature of another video-centric social networking app.
    Type: Application
    Filed: September 25, 2019
    Publication date: February 4, 2021
    Inventors: Geoffrey Cook, Anton Djamoos, David Weinstein, Omar Beiruty, Jeremy Zorn
  • Publication number: 20210002337
    Abstract: Disclosed herein are in vivo engineered cereblon protein and methods of making the same. The in vivo engineered cereblon protein can include a site-specific non-naturally occurring modification at cysteine 287 as set forth in SEQ ID NO:1, or cysteine 286 as set forth in SEQ ID NO: 2 or 3, the modification comprising a moiety resulting from an in vivo Michael addition reaction between an exogenous Michael acceptor and the cysteine 287 as set forth in SEQ ID NO:1, or cysteine 286 as set forth in SEQ ID NO: 2 or 3.
    Type: Application
    Filed: June 16, 2020
    Publication date: January 7, 2021
    Inventors: David WEINSTEIN, Benjamin F. CRAVATT, Matthew PATRICELLI, Dean STAMOS, Gabe SIMON, Benjamin HORNING, Ekaterina VINOGRADOVA, Brian NORDIN, Kristen BALTGALVIS, Todd KINSELLA
  • Patent number: 10869860
    Abstract: Disclosed herein are compositions and methods for modulating cereblon neosubstrates. A small molecule modulator of Formula (I*), or a pharmaceutically acceptable salt or solvate thereof can be used to modulate cereblon neosubstrates.
    Type: Grant
    Filed: July 3, 2019
    Date of Patent: December 22, 2020
    Assignees: VIVIDION THERAPEUTICS, INC., THE SCRIPPS RESEARCH INSTITUTE
    Inventors: Benjamin F. Cravatt, Matthew Patricelli, Dean Stamos, Gabe Simon, Benjamin Horning, David Weinstein, Ekaterina Vinogradova
  • Patent number: 10841323
    Abstract: Methods, systems, and non-transitory computer readable storage media are disclosed for detecting robotic activity while monitoring Internet traffic across a plurality of domains. For example, the disclosed system identifies network session data for each domain of a plurality of domains, the network session data including network sessions comprising features that indicate human activity. In one or more embodiments, the disclosed system generates a classifier to output a probability that a network session at a domain includes human activity. In one or more embodiments, the disclosed system also generates a classifier to output a probability that a network session includes good robotic activity. Additionally, the disclosed system generates a domain-agnostic machine-learning model by combining models from a plurality of domains with network sessions including human activity.
    Type: Grant
    Filed: May 17, 2018
    Date of Patent: November 17, 2020
    Assignee: ADOBE INC.
    Inventors: Ritwik Sinha, Vishwa Vinay, Sunny Dhamnani, Margarita Savova, Lilly Kumari, David Weinstein
  • Patent number: 10783560
    Abstract: Systems and methods disclosed herein generate a segment of tracked entities from a collection of profiles merged from different sources. Individuals and other entities use multiple electronic device and online accounts. Options for merging authentication-based profiles and device-based profiles of tracked entities are presented on a user interface accessible to a tracking entity. Systems and methods receive a selection of the options, the selection specifying criteria for merging authentication-based profiles with device-based profiles. Upon generating a collection of profiles by merging the authentication-based and device-based profiles based on the received options, a targeted segment of tracked entities is generated by applying defined segment rules to the collection of profiles.
    Type: Grant
    Filed: November 4, 2015
    Date of Patent: September 22, 2020
    Assignee: Adobe Inc.
    Inventors: Catalin Costache, Edward Schuchardt, David Weinstein
  • Patent number: 10781239
    Abstract: Disclosed herein are in vivo engineered cereblon protein and methods of making the same. The in vivo engineered cereblon protein can include a site-specific non-naturally occurring modification at cysteine 287 as set forth in SEQ ID NO:1, or cysteine 286 as set forth in SEQ ID NO:2 or 3, the modification comprising a moiety resulting from an in vivo Michael addition reaction between an exogenous Michael acceptor and the cysteine 287 as set forth in SEQ ID NO:1, or cysteine 286 as set forth in SEQ ID NO:2 or 3.
    Type: Grant
    Filed: August 8, 2019
    Date of Patent: September 22, 2020
    Assignees: VIVIDION THERAPEUTICS, INC., THE SCRIPPS RESEARCH INSTITUTE
    Inventors: David Weinstein, Benjamin F. Cravatt, Matthew Patricelli, Dean Stamos, Gabe Simon, Benjamin Horning, Ekaterina Vinogradova, Brian Nordin, Kristen Baltgalvis, Todd Kinsella
  • Publication number: 20200276158
    Abstract: The present invention is directed to a composition for treating alopecia containing minoxidil, cyclosporine A and a compound that binds FK506 binding protein 4 suitable for administration to humans. The present invention is further directed to treating alopecia in humans by administering a composition of the invention.
    Type: Application
    Filed: May 18, 2020
    Publication date: September 3, 2020
    Inventor: David Weinstein