Abstract: The present invention relates to a method for identification of common patient-spanning tumor-specific T cell receptors (TCRs) and their corresponding antigens. The invention also relates to these TCR sequences, a nucleic acid encoding the TCR, and a T cell comprising the TCR and/or the encoding nucleic acid.

Abstract: The present invention relates to novel tri-specific binding molecules. The invention also relates to nucleic acids encoding such binding molecules; to methods for preparing such binding molecules; to host cells expressing or capable of expressing such binding molecules; to compositions comprising such binding molecules; and to uses of such binding molecules or such compositions, in particular for therapeutic purposes in the field of cancer diseases.

Abstract: The present invention relates to novel tri-specific binding molecules. The invention also relates to nucleic acids encoding such binding molecules; to methods for preparing such binding molecules; to host cells expressing or capable of expressing such binding molecules; to compositions comprising such binding molecules; and to uses of such binding molecules or such compositions, in particular for therapeutic purposes in the field of cancer diseases.

Abstract: The invention relates to complement Factor H for use in the prevention and treatment of oxidative stress disease conditions in a patient, the use of Factor H in the preparation of a pharmaceutical preparation, and methods of determining the specific binding of Factor H to MDA and/or MAA in a sample.

Abstract: A plastic conduit bender comprises an integrally molded handle and head portion. A steel hook reinforcement is molded directly into the head portion to provide sufficient force for bending the conduit. Steel reinforcements can also be provided in a grip region of the handle. A plurality of vertical sight lines, indicating bend angles, are provided from an apex molded into the handle and extending to an arcuate shoe portion, allowing the user to gauge the approximate bend angle. A flat surface including rounded saddle portions for receiving the conduit is positioned on the handle to allow the conduit to be bent back or straightened, the rounded saddle contact surfaces preventing damage to the conduit as it is bent back.

Abstract: A plastic conduit bender comprises an integrally molded handle and head portion. A steel hook reinforcement is molded directly into the head portion to provide sufficient force for bending the conduit. Steel reinforcements can also be provided in a grip region of the handle. A plurality of vertical sight lines, indicating bend angles, are provided from an apex molded into the handle and extending to an arcuate shoe portion, allowing the user to gauge the approximate bend angle. A flat surface including rounded saddle portions for receiving the conduit is positioned on the handle to allow the conduit to be bent back or straightened, the rounded saddle contact surfaces preventing damage to the conduit as it is bent back.