Patents by Inventor David Whitcomb
David Whitcomb has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250014752Abstract: A severity calculator analyzes patient information including a patient avatar and a patient state and along with a patient trajectory calculator, computes a predicted outcome which is used to administer treatment. The severity calculator systems and computer program products are also disclosed.Type: ApplicationFiled: September 22, 2023Publication date: January 9, 2025Inventors: Daniel M. SPAGNOLO, David WHITCOMB
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Patent number: 11783949Abstract: A severity calculator analyzes patient information including a patient avatar and a patient state and along with a patient trajectory calculator, computes a predicted outcome which is used to administer treatment. The severity calculator systems and computer program products are also disclosed.Type: GrantFiled: December 2, 2019Date of Patent: October 10, 2023Assignee: Ariel Precision Medicine, Inc.Inventors: Daniel M. Spagnolo, David Whitcomb
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Publication number: 20230201172Abstract: Compositions and methods that can be used to treat recurrent acute pancreatitis or a disease with disordered cystic fibrosis transmembrane conductance regulator (CFTR) function are described herein. For example, pharmaceutical compositions containing a compound of Formula I or a pharmaceutically acceptable salt thereof may be used to treat recurrent acute pancreatitis.Type: ApplicationFiled: May 27, 2021Publication date: June 29, 2023Inventors: David WHITCOMB, Mark HAUPT
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Publication number: 20230138035Abstract: Apparatuses, methods, computer program products, and systems are disclosed for transaction based fraud detection. A method includes receiving, over an application programming interface, an electronic request to perform an action for a user. A method includes electronically accessing one or more attributes of an account for the user. A method includes selectively performing the action for the user based on the one or more attributes of the account.Type: ApplicationFiled: October 31, 2022Publication date: May 4, 2023Applicant: MX Technologies, Inc.Inventors: MICHAEL LOTT, DAVID WHITCOMB
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Publication number: 20220351204Abstract: Apparatuses, methods, computer program products, and systems are disclosed for multi-core account migration. A method includes authenticating a user into a first environment associated with a first core processing system with first electronic credentials for the user. A method includes displaying a user interface element to the user within the first environment. A method includes authenticating the user into a second core processing system in response to user input to the user interface element. A method includes migrating a first account for the user with the first core processing system to a different account for the user with the second core processing system in response to the user input to the user interface element.Type: ApplicationFiled: May 2, 2022Publication date: November 3, 2022Applicant: MX Technologies, Inc.Inventors: DAVID WHITCOMB, MATT NICHOLS
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Publication number: 20220350896Abstract: Apparatuses, methods, computer program products, and systems are disclosed for risk assessment based data access. A method includes determining security risks for each of a plurality of executable applications accessing an application programming interface. A method includes monitoring changes in the security risks for each of the plurality of executable applications. A method includes dynamically adjusting a scope of permissions for the plurality of executable applications with regard to the application programming interface based on the monitored changes in the security risks.Type: ApplicationFiled: May 2, 2022Publication date: November 3, 2022Applicant: MX Technologies, Inc.Inventors: DAVID WHITCOMB, DANIEL D. JONES, BRIAN FROMM
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Publication number: 20220350877Abstract: Apparatuses, methods, computer program products, and systems are disclosed for multi-core account/transaction processing. A method includes authenticating a user with electronic credentials. A method includes querying a first core processing system to determine an identifier for a first account with the first core processing system. A method includes querying a second core processing system to determine a different identifier for a different account with the second core processing system. A method includes accessing the first account with the first core processing system using the first identifier for the user to receive data associated with the first account. A method includes accessing the different account with the second core processing system using the different identifier for the user to receive data associated with the different account. A method includes providing real-time access to both the data associated with the first account and with the different account within a single electronic interface.Type: ApplicationFiled: May 2, 2022Publication date: November 3, 2022Applicant: MX Technologies, Inc.Inventors: DAVID WHITCOMB, MATT NICHOLS
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Publication number: 20200176119Abstract: A severity calculator analyzes patient information including a patient avatar and a patient state and along with a patient trajectory calculator, computes a predicted outcome which is used to administer treatment. The severity calculator systems and computer program products are also disclosed.Type: ApplicationFiled: December 2, 2019Publication date: June 4, 2020Inventors: Daniel M. SPAGNOLO, David WHITCOMB
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Patent number: 10196692Abstract: A polynucleotide comprising at least the final six nucleotides of one of the following primer sequences, or a sequence complementary thereto: SEQ. ID NOS. 3 to 16, 18, 20 to 33, 35 or 37 to 39. A method of detecting the presence or absence of a mutation in the PIK3CA gene, wherein the mutation is one of H1047R, H1047L, E542K and E545K, and preferably ARMS primers are combined with Scorpion primers.Type: GrantFiled: September 18, 2015Date of Patent: February 5, 2019Assignee: QIAGEN MANCHESTER LIMITEDInventors: Ruth Board, Jennifer Haworth, Paul Francis Ravetto, Nicola Jo Thelwell, David Whitcombe
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Patent number: 10190171Abstract: A polynucleotide comprising at least the final six nucleotides of one of the following primer sequences, or a sequence complementary thereto: SEQ. ID NOS. 3 to 16, 18, 20 to 33, 35 or 37 to 39. A method of detecting the presence or absence of a mutation in the PIK3CA gene, wherein the mutation is one of H1047R, H1047L, E542K and E545K, and preferably ARMS primers are combined with Scorpion primers.Type: GrantFiled: September 18, 2015Date of Patent: January 29, 2019Assignee: QIAGEN MANCHESTER LIMITEDInventors: Ruth Board, Jennifer Haworth, Paul Francis Ravetto, Nicola Jo Thelwell, David Whitcombe
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Patent number: 9863003Abstract: A polynucleotide comprising at least the final six nucleotides of one of the following primer sequences, or a sequence complementary thereto: SEQ. ID NOS. 3 to 16, 18, 20 to 33, 35 or 37 to 39. A method of detecting the presence or absence of a mutation in the PIK3CA gene, wherein the mutation is one of H1047R, H1047L, E542K and E545K, and preferably ARMS primers are combined with Scorpion primers.Type: GrantFiled: October 24, 2013Date of Patent: January 9, 2018Assignee: QIAGEN MANCHESTER LIMITEDInventors: Ruth Board, Jennifer Haworth, Paul Francis Ravetto, Nicola Jo Thelwell, David Whitcombe
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Publication number: 20160040255Abstract: A polynucleotide comprising at least the final six nucleotides of one of the following primer sequences, or a sequence complementary thereto: SEQ. ID NOS. 3 to 16, 18, 20 to 33, 35 or 37 to 39. A method of detecting the presence or absence of a mutation in the PIK3CA gene, wherein the mutation is one of H1047R, H1047L, E542K and E545K, and preferably ARMS primers are combined with Scorpion primers.Type: ApplicationFiled: September 18, 2015Publication date: February 11, 2016Inventors: Ruth Board, Jennifer Haworth, Paul Francis Ravetto, Nicola Jo Thelwell, David Whitcombe
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Publication number: 20160032408Abstract: A polynucleotide comprising at least the final six nucleotides of one of the following primer sequences, or a sequence complementary thereto: SEQ. ID NOS. 3 to 16, 18, 20 to 33, 35 or 37 to 39. A method of detecting the presence or absence of a mutation in the PIK3CA gene, wherein the mutation is one of H1047R, H1047L, E542K and E545K, and preferably ARMS primers are combined with Scorpion primers.Type: ApplicationFiled: September 18, 2015Publication date: February 4, 2016Inventors: Ruth Board, Jennifer Haworth, Paul Francis Ravetto, Nicola Jo Thelwell, David Whitcombe
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Patent number: 8901285Abstract: A polynucleotide comprising at least the final six nucleotides of one of the following primer sequences, or a sequence complementary thereto: SEQ. ID NOS. 3 to 16, 18, 20 to 33, 35 or 37 to 39. A method of detecting the presence or absence of a mutation in the PIK3CA gene, wherein the mutation is one of H1047R, H1047L, E542K and E545K, and preferably ARMS primers are combined with Scorpion primers.Type: GrantFiled: September 29, 2008Date of Patent: December 2, 2014Assignee: Qiagen Manchester LimitedInventors: Ruth Board, Jennifer Ferguson, Paul Francis Ravetto, Nicola Jo Thelwell, David Whitcombe
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Publication number: 20110027779Abstract: A polynucleotide comprising at least the final six nucleotides of one of the following primer sequences, or a sequence complementary thereto: SEQ. ID NOS. 3 to 16, 18, 20 to 33, 35 or 37 to 39. A method of detecting the presence or absence of a mutation in the PIK3CA gene, wherein the mutation is one of H1047R, H1047L, E542K and E545K, and preferably ARMS primers are combined with Scorpion primers.Type: ApplicationFiled: September 29, 2008Publication date: February 3, 2011Inventors: Ruth Board, Jennifer Ferguson, Paul Francis Ravetto, Nicola Jo Thelwell, David Whitcombe
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Patent number: 7337683Abstract: A sampling system for separating gaseous samples from a gas stream containing particulate matter and transporting the gaseous samples to a location outside of the flowing gas stream comprises an inertial filter mounted on the end of a hollow probe, the inertial filter positioned within the flowing gaseous stream. The inertial filter comprises a filter media mounted within a tube such that a portion of the particulate-containing gaseous steam flows through an annular space between the filter media and the tube wall, the gas to be sampled passes through the filter media into an inner space and the filtered gas is then delivered through the hollow probe to analytical devices external to the space containing the flowing gas stream, such as a flue stack.Type: GrantFiled: April 27, 2005Date of Patent: March 4, 2008Assignee: M & C Products Analysis Technology, Inc.Inventors: Herbert H. DeFriez, Clifford Gordon, David Whitcomb, Joseph Gregoria
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Publication number: 20070015660Abstract: Non-photosensitive direct thermographic materials comprise a reducing agent that is a catechol borate compound. These compounds can reduce silver(I) ion to metallic silver to produce a dense black silver image under the short time and high temperature conditions that occur when using thermal print-heads during direct thermal printing.Type: ApplicationFiled: July 18, 2005Publication date: January 18, 2007Inventors: Kumars Sakizadeh, Peter Cowdery-Corvan, Leif Olson, David Whitcomb
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Publication number: 20060128566Abstract: Non-photosensitive direct thermographic materials comprise a reducing agent that is a specific ortho-amino-phenol, para-amino-phenol, or hydroquinone compound. These compounds can reduce silver(I) ion to metallic silver to produce a dense black silver image under the short time and high temperature conditions that occur when using thermal print-heads during direct thermal printing. The materials are characterized by their calculated aqueous deprotonation and their calculated anion HOMO energies.Type: ApplicationFiled: December 15, 2004Publication date: June 15, 2006Inventors: David Whitcomb, Leif Olson, Peter Cowdery-Corvan, Kumars Sakizadeh, Takuzo Ishida
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Publication number: 20050241416Abstract: A sampling system for separating gaseous samples from a gas stream containing particulate matter and transporting the gaseous samples to a location outside of the flowing gas stream comprises an inertial filter mounted on the end of a hollow probe, the inertial filter positioned within the flowing gaseous stream. The inertial filter comprises a filter media mounted within a tube such that a portion of the particulate-containing gaseous steam flows through an annular space between the filter media and the tube wall, the gas to be sampled passes through the filter media into an inner space and the filtered gas is then delivered through the hollow probe to analytical devices external to the space containing the flowing gas stream, such as a flue stack.Type: ApplicationFiled: April 27, 2005Publication date: November 3, 2005Inventors: Herbert DeFriez, Clifford Gordon, David Whitcomb, Joseph Gregoria
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Publication number: 20050164219Abstract: A method for the detection of a target nucleic acid, which method comprises contacting template nucleic acid from a sample with (i) a signalling system and (ii) a tailed nucleic acid primer having a template binding region and the tail comprising a linker and a target binding region, in the presence of appropriate nucleoside triphosphates and an agent for polymerisation thereof, under conditions such that the template binding region of the primer will hybridise to a complementary sequence in the template nucleic acid and be extended to form a primer extension product, separating any such product from the template whereupon the target binding region in the tail of the primer will hybridise to a sequence in the primer extension product corresponding to the target nucleic acid, and wherein any such target specific hybridisation causes a detectable change in the signalling system, such that the presence or absence of the target nucleic acid in the sample is detected by reference to the presence or absence of a deType: ApplicationFiled: June 8, 2004Publication date: July 28, 2005Applicant: DXS LimitedInventors: David Whitcombe, Jane Theaker, Neil Gibson, Stephen Little