Patents by Inventor David Wilkes

David Wilkes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20060174323
    Abstract: The invention is directed to techniques to secure interactions between entities communicating on a computer network. In general, techniques are described in which a first entity provides assurances to a second entity that an agent interacting with the second entity is interacting with the second entity on behalf of the first entity. Specifically, the techniques provide the second entity with information tending to indicate that the first entity authorized the agent to perform the interaction with the second entity pursuant to some prior agreement between the two entities. The techniques employ authentication systems and encryption to ensure the security of the interaction.
    Type: Application
    Filed: September 23, 2005
    Publication date: August 3, 2006
    Inventors: Mark Brown, David Wilke
  • Patent number: 6878728
    Abstract: The invention provides novel compounds of formula (I) wherein all variables are as defined in the specification, that are useful as inhibitors of aspartyl proteases.
    Type: Grant
    Filed: June 9, 2000
    Date of Patent: April 12, 2005
    Assignee: Vertex Pharmaceutical Incorporated
    Inventors: Michael R. Hale, Roger Tung, Stephen Price, Robin David Wilkes, Wayne Carl Schairer, Ashley Nicholas Jarvis, Andrew Spaltenstein, Eric Steven Furfine, Vicente Samano, Istvan Kaldor, John Franklin Miller, Michael Stephen Brieger
  • Publication number: 20040122000
    Abstract: The present invention relates to a novel class of sulfonamides which are aspartyl protease inhibitors. In one embodiment, this invention relates to a novel class of HIV aspartyl protease inhibitors characterized by specific structural and physicochemical features. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well suited for inhibiting HIV-1 and HIV-2 protease activity and consequently, may be advantageously used as anti-viral agents against the HIV-1 and HIV-2 viruses. This invention also relates to methods for inhibiting the activity of HIV aspartyl protease using the compounds of this invention and methods for screening compounds for anti-HIV activity.
    Type: Application
    Filed: October 21, 2003
    Publication date: June 24, 2004
    Applicant: Vertex Pharmaceuticals Incorporated.
    Inventors: Michael R. Hale, Roger Tung, Stephen Price, Robin David Wilkes, Wayne Carl Schairer, Ashley Nicholas Jarvis, Andrew Spaltenstein, Eric Steven Furfine, Vicente Samano, Istvan Kaldor, John Franklin Miller, Michael Stephen Brieger, Ronald George Sherrill
  • Patent number: 5689701
    Abstract: A system and method facilitating an operating system user's ability to reference objects in a distributed file system having an incompatible namespace. Compatibility is thereby provided between DFS namespaces and operating system pathname syntax not supported in the DFS. A DFS pathname prefix is associated with each drive letter that is attached to a DFS IFS driver. Before an IFS driver is used, an application program issues a command to associate a drive letter with a particular IFS driver. The command issued also carries a DFS pathname prefix within a data buffer. The IFS services the command by validating existence of the DFS pathname prefix, and thereafter stores such prefix into an internal table of the buffer where it is associated with the attached drive letter. File system requests later received by the DFS client IFS driver carrying a pathname containing that drive letter will have their file specifications edited by the DFS code prior to processing.
    Type: Grant
    Filed: December 14, 1995
    Date of Patent: November 18, 1997
    Assignee: International Business Machines Corporation
    Inventors: Michael Bradford Ault, Ernst Robert Plassmann, Bruce Arland Rich, Michael David Wilkes
  • Patent number: 5493979
    Abstract: A guide mechanism for the roller presser bar of a sewing machine of the type that includes an upper surface roller feeder for imparting movement to the upper work surface and a presser foot that cooperates with the feed dog. The guide mechanism for the roller presser bar is independent of the guide mechanism for the presser foot bar. The independent guide mechanism for the roller presser bar avoids binding of the roller presser bar that occurs when a common guide mechanism is utilized for both the roller presser and the presser foot bar. The roller presser bar guide mechanism includes a pair of movable vertically aligned surfaces attached to the bar and a cooperating block attached to the sewing machine housing with a pair of adjustable guide plates.
    Type: Grant
    Filed: May 3, 1994
    Date of Patent: February 27, 1996
    Assignee: Union Special Corporation
    Inventors: Manfred Ackermann, Troy Vanderhoof, David Wilke