Abstract: In one embodiment, a traffic inspection service executed by an intermediary device obtains, from a monitoring agent executed by an endpoint device, keying information for an encrypted traffic session between the endpoint device and a remote entity. The traffic inspection service provides a notification to the monitoring agent that acknowledges receipt of the keying information. The traffic inspection service uses the keying information to decrypt encrypted traffic from the encrypted traffic session. The traffic inspection service applies a policy to the encrypted traffic session between the endpoint device and the remote entity, based on the decrypted traffic from the session.

Abstract: Nucleic acids encoding fusion proteins that contain an unwanted antigen and a leader sequence for cell secretion are described. Also described are expression cassettes, vectors, cells, and cell lines containing the nucleic acids, as well as methods of using the nucleic acids to treat autoimmune, allergic and other diseases and disorders, such as multiple sclerosis.

Abstract: Disclosed herein are methods for treating a primate in need of tripeptidyl peptidase 1 (TPP1), comprising (a) providing a recombinant adeno-associated virus (AAV) vector comprising a nucleic acid encoding TPP1; and (b) administering an amount of the recombinant AAV vector to the central nervous system (CNS) of the primate, wherein the TPP1 is expressed in the primate.

Abstract: The present invention relates to a series of compounds useful for effecting purification, in particular for use in purification of synthetic peptides and proteins. The compounds of the invention are particularly efficient at securely anchoring peptides or proteins to a surface and allowing the peptide or protein to become uniformly orientated, thus ensuring that substantially all of the peptide or protein is available for molecular binding to a substrate.

Abstract: The present invention relates to a series of compounds useful for effecting purification, in particular for use in purification of synthetic peptides and proteins. The compounds of the invention are particularly efficient at securely anchoring peptides or proteins to a surface and allowing the peptide or protein to become uniformly orientated, thus ensuring that substantially all of the peptide or protein is available for molecular binding to a substrate.

Abstract: Systems and methods for enhancing the cold-formability of Ti 6-2-4-2 sheet material are described herein. Embodiments of these methods comprise cold-forming a predetermined, pretreated Ti 6-2-4-2 alloy into a cold-formed shape; subjecting the cold-formed shape to a post-forming annealing cycle comprising: heating the cold-formed shape to about 1450±25 ° F.; holding the cold-formed shape at about 1450±25° F. for about 15±2 minutes; and cooling the cold-formed shape to room temperature. Embodiments of these methods further comprise subjecting the predetermined Ti 6-2-4-2 alloy to a pre-forming annealing cycle comprising: heating the predetermined alloy to a pre-forming annealing temperature of about 1550-1750° F.; holding the predetermined alloy at the pre-forming annealing temperature for about 30 minutes; and cooling the predetermined alloy to room temperature. These methods allow components comprising 90° bend angles, having a bend factor as low as about 6.2 T, to be achieved.

Abstract: A dehusking apparatus is provided having a fixed cage like housing and a conveyor within the housing for transporting produce from an inlet to an outlet. The conveyor has helical flights with an intermediate portion being covered by a flexible covering between which and the inside of the cage the produce may travel to be dehusked as the produce is conveyed through the apparatus.

Abstract: A pelvic floor muscle weight training kit includes a casing with a cap and a bottom, a set of weights, and a retaining member mounted on each of the weights. The cap has a first inside thread, and the bottom has a second inside thread. Each of the weights is different in shape and weight and is replaced in the casing individually. The retaining member has a third thread. The first and second threads of the casing are capable of being threaded with the third thread of the retaining member such that each of the weights is retained in a universal casing individually. The pelvic floor muscle weight training kit also provides for a method of testing and/or exercising pelvic floor muscles.