Patents by Inventor David Wilson Spence

David Wilson Spence has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant cephalosporin C amidohydrolase in cephalosporin biosynthesis
    Patent number: 6297032
    Abstract: The present invention relates to an enzyme process for the one-step conversion of cephalosporin C or a derivative thereof into 7-aminocephalosporanic acid or a corresponding derivative thereof. The one step conversion is effected using a cephalosphorin C amidohydrolase derived from Pseudomonas Vesicularis B965, or from any cephalosporin C amidolydrolase producing or potentially producing descendants thereof, or from expression of DNA derived from Pseudomonas Vesicularis B965 or any cephalosporin C amidohydrolase producing or potentially producing descendants thereof.
    Type: Grant
    Filed: January 26, 1999
    Date of Patent: October 2, 2001
    Assignee: Glaxo Group Limited
    Inventors: Martin Ramsden, David Wilson Spence
  • Industrial enzymes
    Patent number: 5919648
    Abstract: The present invention relates to an enzyme process for the one-step conversion of cephalosporin C or a derivative thereof into 7-aminocephalosporanic acid or a corresponding derivative thereof.
    Type: Grant
    Filed: April 25, 1997
    Date of Patent: July 6, 1999
    Assignee: Glaxo Group Limited
    Inventors: Keith William Burr, Martin Ramsden, Graham Timothy Illing, Leslie Ann Harrison, Nicholas John Maishman, David Wilson Spence, Andrew Slade