Abstract: A resealable container is provided for storing and dispensing liquids. The container is formed in a one-piece molded construction and includes a cap covering an outlet defined by an externally threaded neck, with a frangible section coupling the cap to the neck. An outer ring is threadedly interfitted over the cap in engagement with the neck, with the outer ring having a plurality of inwardly extending slightly flexible fingers which fit around the cap to captivate the cap. The cap is forced downwardly during downward rotation of the outer ring thereby severing the cap from the neck at the frangible section.

Abstract: A thermoplastic pharmaceutical solution container includes a neck portion having at least one port through the neck portion. A thermoplastic port protector or closure covers the port and defines a frangible section. The closure has a length to diameter ratio providing good mechanical advantage leverage to rupture the frangible section when the closure is pushed sideways. A seal is formed with the closure by forcing a die heated above the melting point of the plastic material into the neck portion, removing a portion of the port protector and forming a depression. The frangible section is formed in the vertical side wall of the depression.

Abstract: A method is provided for forming a fracturable seal of the type wherein a plastic cup-shaped closure is hermetically sealed to a plastic planar surface, such as the neck of pharmaceutical solution containers. The seal is formed with the closure by forcing a die heated above the melting point of the plastic material into the planar surface, with the sealing die also being in heat exchange relationship with a portion of the closure. Both the planar surface and the closure adjacent thereto become molten and the surface material is displaced to form a fused seal transverse to the surface. The surface is depressed at least 0.005 inch from its original height by the sealing action of the die, and a frangible section is formed in the vertical side wall of the depression. The seal will be fractured due to tension stress when the closure is removed from the surface.

Abstract: A plastic container such as a collapsible blood bag or a parenteral solution container may include a flexible sheet member integrally attached to a plastic container and defining lines of tearing weakness for defining and unfolding an elongated sheet member portion, which, in turn, defines a second line of tearing weakness for forming a retaining aperture for receiving a sample tube and the like. Also, the container may have a retention member positioned at each end of the plastic container comprising open, transverse channel means proportioned to receive a length of flexible tubing wound about the ends of said container.

Abstract: A cap closure is provided for bonding to the neck of a container. The cap closure includes a base portion enclosed by a side wall, a peripheral rim extending outwardly from the side wall with the rim being adapted for bonding to the neck of the container, an administration port connected to the base portion, a medication addition port connected to the base portion, a resealable injection site connected to the medication addition port, and port protectors covering and hermetically sealing the administration and medication addition ports. In the illustrative embodiment, the base portion, side wall, peripheral rim, administration port and medication addition ports are molded as an integral, unitary member, and a method is provided for fusing a membrane to the medication addition port and for fusing port protectors with the base member.

Abstract: A screw top closure for a container opening defining a helically threaded neck, and a rotatable screw top positioned to permit rotation by the screw top between outward and inward positions on the neck. A sealing partition is positioned across the opening of the neck. In accordance with this invention, an aperture is defined in the sealing partition, the aperture being positioned in off-center relation to the rotational axis of the screw top. A sealing cap member is positioned across the aperture, with a rupturable seal, facing the screw top. A projection is defined on the side of the screw top facing the partition, being positioned to be longitudinally spaced from the sealing cap member when the screw top is in the outward position, and to engage the sealing cap member when the screw top is rotationally advanced to its inward position. Accordingly, the seal between the cap member and the partition may be ruptured in aseptic manner by the projection, to open the aperture.

Abstract: A thermoplastic pharmaceutical solution container includes a neck portion having at least one port through the neck portion. A thermoplastic port protector or closure covers the port and defines a frangible section. The closure has a length to diameter ratio providing good mechanical advantage leverage to rupture the frangible section when the closure is pushed sideways. A seal is formed with the closure by forcing a die heated above the melting point of the plastic material into the neck portion, removing a portion of the port protector and forming a depression. The frangible section is formed in the vertical side wall of the depression.

Abstract: A thermoplastic pharmaceutical solution container includes a neck portion having at least one port through the neck portion. A thermoplastic port protector or closure covers the port and defines a frangible section. The closure has a length to diameter ratio providing good mechanical advantage leverage to rupture the frangible section when the closure is pushed sideways.

Abstract: A container for storing and dispensing sterile liquids is provided with a hermetically sealed primary cap and overcap. The overcap and primary cap are provided, respectively, with an interlocking ring and undercut lip to provide for limited relative axial movement; the overcap and bottle neck are provided with interfitting lugs and ribs to provide for limited rotational movement. An outer ring has internal threads engaging external threads on the overcap and defines a jacking member whereby rotation of the outer ring moves the overcap upwardly to break the hermetic seals.

Abstract: A one-piece hanger for a container comprises attachment means to a container and an elongated, flexible hanger member secured at both ends to the attaching means to define a closed loop. The elongated hanger member is positioned in generally longitudinal relationship to the attaching means and defines a pair of first flex sections positioned respectively adjacent the ends of the hanger members, and a pair of spaced second flex sections positioned more remotely from the ends of the flexible hanger member. Accordingly, the hanger member is generally approximately coplanar with the attachment means so that it does not project upwardly away from the container which carries it. However, the hanger can be bent into transverse relation to the attachment means to unfold and expose a large loop for hanging of the container.

Abstract: A container for storing and dispensing sterile liquids is provided with a hermetically sealed overcap. An outer ring fits over the overcap and the overcap and outer ring have interfitting threads. The outer ring defines a jacking member for moving the overcap axially upwardly on a bottle neck when the outer ring is rotated downwardly. Antibackoff means are provided for axially interlocking the outer ring and overcap, limiting upward rotational displacement of the outer ring with respect to the overcap.

Abstract: A ratchet mechanism is provided for preventing disassembly of an outer ring used to jack a hermetically sealed overcap from the neck of a container. The ratchet mechanism comprises a set of teeth on the outer ring which act in cooperation with a set of teeth on the overcap thereby providing a means for preventing rotation of the outer ring in a direction tending to unscrew the outer ring from the overcap, but permitting rotation of the outer ring in the jacking direction.

Abstract: A supplemental additive indication cap for installation about a tubular access port of a container, which defines at one end thereof gripper means such as gripper arms for engaging the access port, to prevent removal of the cap after installation. An auxiliary sleeve is carried by the cap for enclosing the gripper means, to prevent the manual disengagement of the gripper means from the access port and removal of the cap, and also to force the gripper means into engagement with the access port. The cap prevents the addition of further additives such as medication to a parenteral solution container after it is installed.

Abstract: There is provided an improved means and method for attaching a flexible tube to a container of the type having a stub tube port with an end of the tube fitted over the stub port. The attaching means includes a resilient ring tightly fitted over the tube end and a retainer cap fitted over the ring and bonded to the container.

Abstract: A protector cap for establishing a sterile seal over a port having a puncturable section in a container wall and a cylindrical neck portion projecting from the periphery of the wall section. The cap comprises a molded housing having a ring-shaped recess for sealingly engaging the neck member and a chamber formed at least in part within a compressible handle portion. The handle portion is compressed prior to inserting the cap on the neck portion of the port and is subsequently released to establish a partial vacuum in the chamber. The partial vacuum assists in retaining the protector cap in position and prevents trapped air from forcing the cap off during subsequent heat-sterilization of the container.