Patents by Inventor David Winkler

David Winkler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7592429
    Abstract: Compositions and methods relating to epitopes of sclerostin protein, and sclerostin binding agents, such as antibodies capable of binding to sclerostin, are provided.
    Type: Grant
    Filed: April 25, 2006
    Date of Patent: September 22, 2009
    Assignees: UCB SA, Amgen Inc.
    Inventors: Christopher Paszty, Martyn Kim Robinson, Kevin Graham, Alistair James Henry, Kelly Sue Hoffmann, John Latham, Hsieng Sen Lu, Alastair Lawson, Andy Popplewell, Wenyan Shen, David Winkler, Aaron George Winters
  • Publication number: 20080081234
    Abstract: A gating device (100) and associated method (900) for identifying a fuel container (101) used to refill a fuel cell (102) are presented. A fuel source identification device (103) identifies a fuel container (101) to verify that it is compatible with the fuel cell (102). Upon identification, a gating engine (105) opens a retractable barrier (106), thereby providing access to the fuel cell (102). The gating engine (105) moves the retractable barrier (106) from a closed position to an open position when a control circuit (803) indicates that the fuel container (101) is compatible with the fuel cell (102). The fuel container identification device may be an impedance detector (201), a connectivity detector (301), a barcode reader (401), a memory reader (501), a radio-frequency identification device (601), a label reader (701), or other similar device.
    Type: Application
    Filed: October 2, 2006
    Publication date: April 3, 2008
    Inventor: David A. Winkler
  • Publication number: 20070152630
    Abstract: Disclosed are methods and devices in a battery powered electronic device (202) for hot swapping batteries, the battery powered electronic device having a battery holder (210) with a first connector (203) and a second connector (205), and having a first battery (204) in contact with both the first connector (203) and the second connector (205). The method includes maintaining power to the device from a first battery (706). The method also includes partially moving the first battery out of the battery holder in a predetermined direction to break contact with the first connector (712) while maintaining contact with the second connector (714). The method further includes partially inserting a second battery into the battery holder in the predetermined direction so that the second battery is received by the battery holder and makes contact with the first connector (712). In another embodiment the method includes charging one or another battery through the first connector or the second connector.
    Type: Application
    Filed: December 29, 2005
    Publication date: July 5, 2007
    Inventors: David Winkler, Mark Barabolak, Bokchain Koh, Arthur Leyh, Edward Naddeo
  • Publication number: 20070110747
    Abstract: Compositions and methods relating to epitopes of sclerostin protein, and sclerostin binding agents, such as antibodies capable of binding to sclerostin, are provided.
    Type: Application
    Filed: April 25, 2006
    Publication date: May 17, 2007
    Applicants: UCB S.A., Amgen, Inc.
    Inventors: Christopher Paszty, Martyn Robinson, Kevin Graham, Alistair Henry, Kelly Hoffmann, John Latham, Hsieng Lu, Alastair Lawson, Andy Popplewell, Wenyan Shen, David Winkler, Aaron Winters
  • Publication number: 20070099232
    Abstract: The present invention relates to structural studies of the functional insect ecdysone receptor. More particularly, the invention relates to the crystal structure of the whitefly ecdysone receptor ligand-binding domain, specifically that of Bemisia tabaci, and uses of the crystal and related structural information to select and screen for compounds that interact with the receptor.
    Type: Application
    Filed: May 27, 2004
    Publication date: May 3, 2007
    Inventors: Michael Lawrence, Patricia Pilling, George Lovrecz, Vidana Epa, Jennifer Camichael, Leonie Noyce, Lloyd Graham, Garry Hannan, David Winkler, Ronald Hill
  • Publication number: 20070072797
    Abstract: Compositions and methods relating to epitopes of sclerostin protein, and sclerostin binding agents, such as antibodies capable of binding to sclerostin, are provided.
    Type: Application
    Filed: April 25, 2006
    Publication date: March 29, 2007
    Applicants: UCB S.A., Amgen, Inc.
    Inventors: Martyn Robinson, Alistair Henry, Alastair Lawson, Hsieng Lu, Christopher Paszty, Kelly Hoffmann, John Latham, David Winkler, Aaron Winters
  • Publication number: 20070005551
    Abstract: A system and computer-implemented method for the creation of a structure using Lego building blocks is disclosed. Aspects of the methods are equally appropriate for numerous structures, including but not limited to, studs-up and studs-out configurations or a ‘wall’ style mosaic or a ‘floor’ style mosaic. Given the systems and methods disclosed, aspects of the invention are applicable to three-dimensional sculpture structures too. The system and method may use a recursive overlapping divide-and-conquer breadth-first search feature to improve the quality of the structures while only slightly, if at all, increasing the time and memory required. Furthermore, the system and method may use dithering algorithms and/or cost analysis to determine which building block can be used and placed to achieve high-quality structures. In another example, aspects of the invention may be used to more optimally schedule delivery trucks.
    Type: Application
    Filed: June 29, 2005
    Publication date: January 4, 2007
    Applicant: Microsoft Corporation
    Inventor: David Winkler
  • Publication number: 20060233801
    Abstract: A novel class or family of TGF-? binding proteins is disclosed. Also disclosed are assays for selecting molecules for increasing bone mineralization and methods for utilizing such molecules. In particular, compositions and methods relating to antibodies that specifically bind to TGF-beta binding proteins are provided. These methods and compositions relate to altering bone mineral density by interfering with the interaction between a TGF-beta binding protein sclerostin and a TGF-beta superfamily member, particularly a bone morphogenic protein. Increasing bone mineral density has uses in diseases and conditions in which low bone mineral density typifies the condition, such as osteopenia, osteoporosis, and bone fractures.
    Type: Application
    Filed: April 5, 2006
    Publication date: October 19, 2006
    Inventors: Mary Brunkow, David Galas, Brian Kovacevich, John Mulligan, Bryan Paeper, Jeffrey Ness, David Winkler
  • Publication number: 20060119129
    Abstract: A retractable awning for attachment to a golf cart is provided. The awning is comprised of a framework having a plurality of U-shaped rib members and a fabric cover. The U-shaped rib members have ends terminating at a common pivot point to allow respective relative movement to move the awning between an extended deployed position and a retracted closed position over a rear compartment of the golf cart. Each successively adjacent rib member is dimensioned slightly less than its preceding rib member to allow nesting of all the rib members in a common plane so that the framework can lie substantially flat in its retracted position. A tab on the fabric cover allows an operator to move and secure the framework between an extended position, whereat a rear portion of the cart is covered, and a retracted position, whereat the rear portion of the cart is exposed.
    Type: Application
    Filed: January 27, 2006
    Publication date: June 8, 2006
    Inventor: David Winkler
  • Publication number: 20060123159
    Abstract: Systems, methods, and computer-readable media process computer input data (such as electronic ink data, speech input data, keyboard input data, etc.), including focus change data, in a manner so that the input insertion range better comports with the user's original intent. More specifically, user input data may be accepted, before, during, and/or after a focus change event is initiated, and the systems and methods will process this input data in an intuitive manner, directing the data to areas of an application program or the operating system that better comport with the user's original intent. In this manner, loss of input data may be avoided and misdirected input data may be avoided, thereby lowering user frustration during focus change events.
    Type: Application
    Filed: November 19, 2004
    Publication date: June 8, 2006
    Applicant: Microsoft Corporation
    Inventors: Josh Clow, Adrian Garside, David Winkler
  • Publication number: 20060112349
    Abstract: Systems, methods, and computer-readable media process computer input data (such as electronic ink data, speech input data, keyboard input data, etc.), including focus change data, in a manner so that the input insertion range better comports with the user's original intent. More specifically, user input data may be accepted, before, during, and/or after a focus change event is initiated, and the systems and methods will process this input data in an intuitive manner, directing the data to areas of an application program or the operating system that better comport with the user's original intent. In this manner, loss of input data may be avoided and misdirected input data may be avoided, thereby lowering user frustration during focus change events.
    Type: Application
    Filed: November 19, 2004
    Publication date: May 25, 2006
    Applicant: Microsoft Corporation
    Inventors: Josh Clow, Adrian Garside, David Winkler
  • Publication number: 20050273713
    Abstract: A correction tool that displays a correction widget when a user acts to correct text is provided. More particularly, if the user places an insertion point in or to the immediate left of the text, or selects the text, the tool displays the correction widget immediately to the left of the selected text. The user can then quickly access a correction interface for correcting the text simply by moving the pointer the short distance from the insertion point to the correction widget. When the user activates the correction widget, the tool displays the correction interface immediately proximal to the correction widget. Thus, the user need only move the pointer a small distance further to then correct the text using the correction interface.
    Type: Application
    Filed: July 27, 2005
    Publication date: December 8, 2005
    Applicant: Microsoft Corporation
    Inventors: Ravipal Soin, Adrian Garside, David Winkler, Luis Huapaya, Marieke Iwema
  • Publication number: 20050262442
    Abstract: A correction tool that displays a correction widget when a user acts to correct text is provided. More particularly, if the user places an insertion point in or to the immediate left of the text, or selects the text, the tool displays the correction widget immediately to the left of the selected text. The user can then quickly access a correction interface for correcting the text simply by moving the pointer the short distance from the insertion point to the correction widget. When the user activates the correction widget, the tool displays the correction interface immediately proximal to the correction widget. Thus, the user need only move the pointer a small distance further to then correct the text using the correction interface.
    Type: Application
    Filed: July 27, 2005
    Publication date: November 24, 2005
    Applicant: Microsoft Corporation
    Inventors: Ravipal Soin, Adrian Garside, David Winkler, Luis Huapaya, Marieke Iwema
  • Publication number: 20050106683
    Abstract: Compositions and methods relating to antibodies that specifically bind to TGF-beta binding proteins are provided. These methods and compositions relate to altering bone mineral density by interfering with the interaction between a TGF-beta binding protein sclerostin and a TGF-beta superfamily member, particularly a bone morphogenic protein. Increasing bone mineral density has uses in diseases and conditions in which low bone mineral density typifies the condition, such as osteopenia, osteoporosis, and bone fractures.
    Type: Application
    Filed: June 15, 2004
    Publication date: May 19, 2005
    Applicant: Celltech R & D Limited
    Inventors: David Winkler, Jiye Shi, John Latham
  • Publication number: 20050099398
    Abstract: Systems and methods enhance editing capabilities associated with a wide variety of different types of electronic documents. Such systems and methods may include a processor that maintains an electronic document having a first portion (e.g., an individual word, character, character string, or the like) provided by a recognizer (e.g., by handwriting or speech recognition software), and they may provide access to potential alternative characters, words, or character strings generated by the recognizer during various user editing functions and operations. Other data associated with the first portion of the document also may be stored and made available to the user during various functions and operations. This invention further relates to computer-readable media including instructions for performing various methods and/or operating various systems for editing electronic documents, including systems and methods like those described above.
    Type: Application
    Filed: November 7, 2003
    Publication date: May 12, 2005
    Applicant: Microsoft Corporation
    Inventors: Adrian Garside, David Winkler, Joshua Clow
  • Publication number: 20050085418
    Abstract: Compositions and methods are provided that relate to the unexpected specific association of (i) the TGF-beta binding protein sclerostin with the BMP antagonist protein chordin to form a complex, and of (ii) the TGF-beta binding protein sclerostin with the BMP antagonist protein noggin to form a complex, either of which complex is incapable of binding to a TGF-beta superfamily member such as a BMP. The invention provides isolated complexes for use in screening assays to identify agents that modulate bone mineralization, and offers other related advantages.
    Type: Application
    Filed: March 12, 2004
    Publication date: April 21, 2005
    Applicant: CELLTECH R & D LTD.
    Inventors: David Winkler, John Latham, John Skonier, Diana Shpektor, Trenton Hayes, James Geoghegan
  • Publication number: 20050080807
    Abstract: A tool for creating integrated collections. The tool may include a “basket” control that includes interfaces for receiving and displaying the data objects that are selected by a user to be included in a collection, and a collection creation component then provides a collection with one or more data items corresponding to the objects submitted to the basket control. The basket control may be employed by itself to make collections, or it may be hosted by another software object, such as a “listmaker” control that conveniently contains both the basket control and one or more user interfaces that a user can employ to provide data objects to the basket control. The listmaker control may thus include a viewing graphical user interface for viewing data objects and a navigation toolbar for navigating the viewing graphical user interface. The listmaker control may then be hosted as desired in a variety of software applications.
    Type: Application
    Filed: October 12, 2003
    Publication date: April 14, 2005
    Applicant: Microsoft Corporation
    Inventors: Craig Beilinson, Christopher Evans, David Winkler, Jae Park, Emily Buchanan, Jared Henderson, Jeffrey Belt, Pritvinath Obla, Anthony Chor, William Gould, Shabbir Shahpurwala, Relja Ivanovic
  • Patent number: 6451785
    Abstract: A method of inhibiting or reducing cell proliferation in a human or mammal is disclosed. This method involves administering to a human or mammal an effective amount of CoA-independent transacylase inhibiting amount of a compound of the formula disclosed in the specification.
    Type: Grant
    Filed: January 28, 2000
    Date of Patent: September 17, 2002
    Assignees: SmithKline Beecham Corporation, Wake Forest University
    Inventors: James David Winkler, Floyd Harold Chilton, III
  • Publication number: 20020082250
    Abstract: This invention relates to a method of treating or reducing cell proliferation in a mammal in need thereof which comprises administering to said mammal an effective CoA-independent transacylase (CoA-IT) inhibiting amount of a compound of formula (I), wherein the variables of Y, X, m, R 3, R 4, R 10, R 20, R 5, R 6 and R 7 are defined in the specification. FIG. 3 demonstrates the ability of SB216754, ((3S,4R)-4-(isobutenyloxy)-3-triphenylmethylamino)azetidin-2-one) to decrease the viability of HL-60 cells.
    Type: Application
    Filed: January 28, 2000
    Publication date: June 27, 2002
    Inventors: JAMES DAVID WINKLER, FLOYD HAROLD CHILTON III
  • Patent number: 6221860
    Abstract: This invention relates to methods for treating diseases or disorders mediated by lipid inflammatory mediators, arachidonic acid, its metabolites and/or platelet activating factor (PAF), which method comprises administration to a mammal in need thereof of an effective Coenzyme A independent transacylase (CoA-IT) inhibiting amount of a triphenylmethylazetidinone. This invention also relates to a method of treating or reducing inflammation in a mammal in need thereof, which comprises administering to said mammal an effective amount of a triphenylmethylazetidinone.
    Type: Grant
    Filed: November 8, 1999
    Date of Patent: April 24, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: William E. Bondinell, James David Winkler