Abstract: Electrophoresis is used to identify presence of a target compound in a patient sample based on a charge state of the compound and a label. The charge state of the compound correlates to a total net charge of a binder conjugated to the compound. The bound complex or “bound complex” with the label is then applied to the electrophoresis substrate. An electric potential is applied to the substrate for a time period and causes the labeled bound complex to migrate toward the electrode with opposite charge of the labeled bound complex at a migration velocity to form a migration pattern over the time period. At some time during or at the end of the time period, the labeled bound complex produces a bound complex band as a result of its migration across the substrate. The presence of the compound is identified based on the labeled bound complex band and one or both of the migration pattern and the migration velocity.

Abstract: A computer implemented method for distributing, collecting and monitoring assignments by a content management system. The method includes receiving a request for a file request from a teacher to distribute an assignment to one or more students. In response to receiving the request, the teacher is prompted for information associated with the assignment. The information can include a name for the assignment, an assignment file and a collection identifier. In response to receiving the information, one or more metadata tags are generated based on the received information. The file request is distributed along with the one or more metadata tags to the one or more student.

Abstract: A signal assembly is provided that includes a chamber defined by isotropically luminant back and side surfaces, and a front surface having a lens and a diffuser. The signal assembly also includes LED light sources having a beam angle ?70° coupled to the back surface. The back and front surfaces are separated by a depth, and each source is located at a spacing from the other sources ?the depth divided by a predetermined factor. The predetermined factor may be set to approximately 2.5 or 2.0 when the divergence angle of the diffuser is ?20° or ?30°, respectively. The signal assembly and its components can be configured to operate as a vehicular signal lamp.

Abstract: A signal assembly is provided that includes a chamber defined by isotropically luminant back and side surfaces, and a front surface having a lens and a diffuser. The signal assembly also includes LED light sources having a beam angle ?70° coupled to the back surface. The back and front surfaces are separated by a depth, and each source is located at a spacing from the other sources?the depth divided by a predetermined factor. The predetermined factor may be set to approximately 2.5 or 2.0 when the divergence angle of the diffuser is ?20° or ?30°, respectively. The signal assembly and its components can be configured to operate as a vehicular signal lamp.

Abstract: Methods for classifying a test sample as indicative of Alzheimer's disease use protein and peptide biomarkers that are differentially expressed in the cerebral spinal fluid (CSF) of subjects with Alzheimer's disease relative to age-matched controls. The methods also use protein and peptide signatures indicative of Alzheimer's disease. Microarrays and kits for detecting the protein and peptide biomarkers in CSF samples can be used to classify Alzheimer's disease state from test samples.

Abstract: The present invention provides novel compositions comprising Epstein-Barr virus-specific oligonucleotides that are useful as primers to amplify particular regions of the genome during enzymatic nucleic acid amplification. The invention also provides a rapid, sensitive and specific method for the detection and quantitation of the virus which may be present in a clinical specimen, using the virus-specific primers and enzymatic nucleic acid amplification; hybridization of amplified target sequences, if present, with one or more Epstein-Barr virus-specific oligonucleotide probes which are labeled with a detectable moiety; and detection of the detectable moiety of labeled oligonucleotide probe hybridized to amplified target sequences of Epstein-Barr virus DNA.