Abstract: Provided herein is a device for detecting the presence of pathogens in a sample and methods of use thereof. The device and method comprises one or more amplification components, an indicator, and a sensor (e.g., a pH sensitive polymer). Contacting a sample with the one or more amplification components, the indicator, and the sensor (e.g., a pH sensitive polymer) in a first region of the device and subjecting the sample to an amplification method may lead to a change in pH, releasing the indicator to flow towards a second region of the device, which generates a visually detectable signal and indicates the presence of a pathogen.

Abstract: Disclosed herein are system, method, and computer program product embodiments for creating and utilizing machine learning models to generate a provider performance index. In some embodiments, a first and second target may be selected. The first and second targets may respectfully include target values. First and second adjusted target values may be determined by combining the first and second target values with first and second external weights. The external weights may be generated by respective first and second machine learning models. The machine learning models may correspond to the respective targets. First and second error values may be determined based on differences between respective target and adjusted target values. The error values may be normalized and combined to generate an index value.

Abstract: A method of detecting a pathogen in a fluid sample includes adding the fluid sample to a first region of an assembly; amplifying a polynucleotide sequence of a pathogen in the first region using an amplification method; and detecting a presence of the pathogen by one of the following. Identifying a release of a dye from a pH sensitive polymer. Or, identifying a release of a dye from the first region to a second region that are separated by a pH sensitive polymer. Or, activating a pH sensitive dye in the first region to indicate a presence of the pathogen. Or, indicating a presence of the pathogen on a lateral flow assay in a second region that is separated from the first region by a pH sensitive polymer. Each identification, activation, or indication step occurs after the amplification method adjusts a pH of the fluid sample.

Abstract: The present disclosure relates to a computer-implemented method for determining a real time steering angle (58) for a railway bogie (1) and to a control device (40) which is configured to perform the method, the method comprising: deter-mining by a sensor assembly at least one lateral real time sensor signal (38), which is characteristic for a lateral position of a tread of at least one wheel of the railway bogie (1) with respect to a railway track, determining, by means of a positioning algorithm (47), a real time position and/or orientation of the railway bogie (1) with respect to the railway track (31), using the received at least one lateral real time sensor signal (38) and determining the real time steering angle (58) for steering of the railway bogie (1), using the determined real time position and/or orientation of the railway bogie (1).

Abstract: Systems and methods for obtaining a transmission of a first data packet, requesting one or more available physical locations based on the first data packet, determining the first configuration based on the first data packet and the one or more available physical locations, and causing to output the first configuration to a user interface.

Abstract: Provided herein is an apparatus for the detection of analytes. In some embodiments, the analyte to be detected consists of nucleotide sequences. In some embodiments, the analytes are detected in liquid solutions. In some embodiments, the apparatus comprises a stage, a light source, a spectrometer, and a lens assembly.

Abstract: A castable, moldable, and/or extrudable structure using a metallic primary alloy. One or more additives are added to the metallic primary alloy so that in situ galvanically-active reinforcement particles are formed in the melt or on cooling from the melt. The composite contains an optimal composition and morphology to achieve a specific galvanic corrosion rate in the entire composite. The in situ formed galvanically-active particles can be used to enhance mechanical properties of the composite, such as ductility and/or tensile strength. The final casting can also be enhanced by heat treatment, as well as deformation processing such as extrusion, forging, or rolling, to further improve the strength of the final composite over the as-cast material.

Abstract: The present invention relates to the composition and production of an engineered degradable metal matrix composite that is useful in constructing temporary systems requiring wear resistance, high hardness, and/or high resistance to deformation in water-bearing applications such as, but not limited to, oil and gas completion operations.

Abstract: Charging station mounted fire extinguishing facilitating apparatus, comprising a plurality of spaced interconnected partitions fixedly mounted at a charging station that define an interior volume within which an electric bicycle battery is introducible and rechargeable, and one or more peripheral cavities in communication with the interior volume, within each of the cavities a sealed heat sensitive package containing a flowable fire extinguishing material is receivable, wherein the heat sensitive package is confined by the partitions defining the cavity within which it is received so as to remain in positional relation with the interior volume and is configured to be sufficiently deformed so as to become perforated in at least one package region during exposure to a predetermined fire-induced temperature when the battery is inflamed, thereby allowing the contained fire extinguishing material to be discharged from the package via a perforation at the at least one package region, to flow into the interior volum

Abstract: Described herein is a technology for the creation of “smooth” metal oxide films or coatings using organic cross-linking agents to enable low-temperature sintering. These metal oxide films can be used in conjunction with low-melting temperature substrates, such as plastics, metal, metal oxide, and glass, providing exquisite control over surface roughness.

Abstract: A low osmolality oral rehydration slush composition is provided. The oral rehydration slush composition includes: water; a source of carbohydrate; a source of electrolytes; and a source of citrate. The oral rehydration slush composition has an osmolality of 70 mOsm/kg H2O to 350 mOsm/kg H2O. The oral rehydration slush composition can be used to treat individuals suffering from dehydration.

Abstract: The present invention relates to the composition and production of an engineered degradable metal matrix composite that is useful in constructing temporary systems requiring wear resistance, high hardness, and/or high resistance to deformation in water-bearing applications such as, but not limited to, oil and gas completion operations.

Abstract: A system for intelligently processing queries for cloud-based network file stores includes a file store that stores groups of documents that are associated with files, a non-transitory storage medium that stores instructions, and a processor. The processor may execute the instructions to receive a ticket based on a communication associated with a query to the file store, pull data for the ticket, check a sender of the communication, identify a file using the data, and/or analyze the communication using an artificial intelligence engine to generate a recommendation. The processor may monitor changes to the recommendation made before being sent in order to update the artificial intelligence engine for the changes.

Abstract: Exemplary embodiments relate to methods, mediums, and systems for associating information, including critical-to-quality (CTQ) information such as minimum or maximum part dimensions, with parts in a three-dimensional model of a product. The information may be identified by performing a failure mode effect analysis (FMEA) against the model. The information is stored with the model data (e.g., in the form of an annotation applied to a model feature corresponding to the part in question). The model data may be consulted by product lifecycle management (PLM) applications during various phases of the product's lifecycle. Among other possibilities, the information may be used to automatically generate regulatory compliance documentation, to ensure product quality standards are met during a manufacturing process, or to perform postproduction quality monitoring of the product.

Abstract: A server-client architecture including a host server and a client device. The client device executes a client application that communicably couples to the host server. The host server is configured to receive an input including information related to a particular asset, such as a real property. The host server is configured to access one or more third party databases to enumerate encumbrances upon a seller's title to the particular asset and, in response, generate a grading of a property based on, without limitation, the (1) number and (2) type of encumbrances identified by the third party databases. The grading is thereafter transmitted to the client device for display to a user of the client device.

Abstract: A tastable, moldable, and/or extrudable structure using a metallic primary alloy. One or more additives are added to the metallic primary alloy so that in situ galvanically-active reinforcement particles are formed in the melt or on cooling from the melt. The composite contains an optimal composition and morphology to achieve a specific galvanic corrosion rate in the entire composite. The in situ formed galvanically-active particles can be used to enhance mechanical properties of the composite, such as ductility and/or tensile strength. The final casting can also be enhanced by heat treatment, as well as deformation processing such as extrusion, forging, or rolling, to further improve the strength of the final composite over the as-cast material.

Abstract: A castable, moldable, and/or extrudable structure using a metallic primary alloy. One or more additives are added to the metallic primary alloy so that in situ galvanically-active reinforcement particles are formed in the melt or on cooling from the melt. The composite contains an optimal composition and morphology to achieve a specific galvanic corrosion rate in the entire composite. The in situ formed galvanically-active particles can be used to enhance mechanical properties of the composite, such as ductility and/or tensile strength. The final casting can also he enhanced by heat treatment, as well as deformation processing such as extrusion, forging, or rolling, to further improve the strength of the final composite over the as-cast material.

Abstract: Disclosed herein are methods and systems for use in database hosting and other systems, such as systems for real estate and other transactions with distributed clients. The methods and systems are directed to maintaining and updating core data to ensure all clients and users have correct data for the transactions. Core data is maintained and updated, in part, by use of append-only ledger systems that assigns a unique identifier to events (inputs) received from users. Such methods and system may be implemented by a cloud-based hosting service. The methods and systems may use an append-only ledger and support schema validation, subscriptions and event replay. The replay of events from the ledger may use a subscription and replay fanout tables.

Abstract: The present invention relates to the composition and production of an engineered degradable metal matrix composite that is useful in constructing temporary systems requiring wear resistance, high hardness, and/or high resistance to deformation in water-bearing applications such as, but not limited to, oil and gas completion operations.

Abstract: The present invention relates to the composition and production of an engineered degradable metal matrix composite that is useful in constructing temporary systems requiring wear resistance, high hardness, and/or high resistance to deformation in water-bearing applications such as, but not limited to, oil and gas completion operations.