Patents by Inventor David Woo
David Woo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20240131012Abstract: The present invention provides compounds, compositions thereof, and methods of using the same.Type: ApplicationFiled: November 1, 2023Publication date: April 25, 2024Inventors: David John O'NEILL, Eddine SAIAH, Seong Woo Anthony KANG
-
Patent number: 11963909Abstract: A method and surgical system including a laser source for generating a pulsed laser beam, an imaging system including a detector, shared optics configured for directing the pulsed laser beam to an object to be sampled and confocally deflecting back-reflected light from the object to the detector, a patient interface, through which the pulsed laser beam is directed, the patient interface having, a cup with a large and small opening, and a notched ring inside the cup; and a controller operatively coupled to the laser source, the imaging system and the shared optics, the controller configured to align the eye for procedure.Type: GrantFiled: October 14, 2019Date of Patent: April 23, 2024Assignee: AMO Development, LLCInventors: John S. Hart, David A. Dewey, Georg Schuele, Phillip H. Gooding, Christine J. Beltran, Javier G. Gonzalez, Katrina B. Sheehy, Jeffrey A. Golda, Raymond Woo, Madeleine C. O'Meara, Noah Bareket, Thomas Z. Teisseyre, Bruce Woodley
-
Publication number: 20240115147Abstract: A system and method are provided for determining a pressure associated with a lumen of a body. A wireless sensor is positioned in the lumen of the body. The sensor comprises an LC resonant circuit having a resonant frequency configured to vary in response to changes in pressure in the lumen. One or more sensor calibration parameters are stored at an external base unit. The external based unit generates and transmits an energizing signal. A ring down response is received from the wireless sensor. The system and method determine the resonant frequency of the LC resonant circuit from the ring down response and calculate the pressure in the lumen from the resonant frequency of the LC resonant circuit utilizing the one or more sensor calibration parameters associated with the LC resonant circuit.Type: ApplicationFiled: December 19, 2023Publication date: April 11, 2024Inventors: Florent Cros, David O'Brien, Michael Fonseca, Matthew Abercrombie, Jin Woo Park, Angad Singh
-
Patent number: 11944605Abstract: The present invention provides compounds, compositions thereof, and methods of using the same.Type: GrantFiled: November 25, 2020Date of Patent: April 2, 2024Assignee: Janssen Pharmaceutica NVInventors: Eddine Saiah, David John O'Neill, Seong Woo Anthony Kang
-
Patent number: 11939680Abstract: A method includes applying a material coating on a surface of a machine component using a thermal spray, wherein the material coating is formed from a combination of a hardfacing material and aluminum-containing particles. The method also includes thermally treating the material coating to generate an oxide layer comprising aluminum from the aluminum-containing particles, wherein the oxide layer is configured to reduce oxidation of the hardfacing material.Type: GrantFiled: March 8, 2023Date of Patent: March 26, 2024Assignee: GE Infrastructure Technology LLCInventors: Krishnamurthy Anand, Surinder Singh Pabla, Lacey Lynn Schwab, Biju Dasan, Seung-Woo Choi, Sathisha Chikkabikkodu Hanum, Ravikiran Kopparthi, David Vincent Bucci
-
Publication number: 20240098969Abstract: Systems, methods and apparatus are provided for an array of vertically stacked memory cells having horizontally oriented access devices and storage nodes formed in tiers. And, more particularly, to multiple, alternating silicon germanium (SiGe) and single crystalline silicon (Si) in different thicknesses to form tiers in which to form the horizontal access devices in vertical three-dimensional (3D) memory. The horizontally oriented access devices can have a first source/drain regions and a second source drain regions separated by single crystalline silicon (Si) channel regions. The single crystalline silicon (Si) channel regions can include a dielectric material to provide support structure to the single crystalline channel regions when forming the horizontal access devices in vertical three-dimensional (3D) memory. Horizontally oriented access lines can connect to gate structures opposing the channel regions. Vertical digit lines coupled to the first source/drain regions.Type: ApplicationFiled: September 15, 2022Publication date: March 21, 2024Inventors: David K. Hwang, Yoshitaka Nakamura, Scott E. Sills, Si-Woo Lee, Yuanzhi Ma, Glen H. Walters
-
Publication number: 20240098970Abstract: Systems, methods and apparatus are provided for an array of vertically stacked memory cells having horizontally oriented access devices and storage nodes. The horizontally oriented access devices having a first source/drain regions and a second source drain regions separated by silicon (Si) channel regions. A digit line having a global digit line (GDL) contact is formed in a trench adjacent to the first source/drain regions. In one example, the digit line is electrically isolated from a neighboring digit line at the bottom of the trench. In another example, the digit line is formed continuously along a bottom surface of trench to form shared digit lines between horizontal access devices, in two separate arrays, on opposing second vertical surfaces. The memory cells have horizontally oriented storage nodes coupled to the second source/drain regions and vertical digit lines coupled to the first source/drain regions.Type: ApplicationFiled: September 16, 2022Publication date: March 21, 2024Inventors: Scott E. Sills, Si-Woo Lee, David K. Hwang, Yoshitaka Nakamura, Yuanzhi Ma, Glen H. Walters
-
Publication number: 20240074141Abstract: Methods and devices for a lateral three-dimensional memory device, are described herein. One method includes forming a thin film transistor including a first thermal process having a first range of temperatures, forming a capacitor bottom electrode of a capacitor structure including a second thermal process having a second range of temperature, wherein a maximum temperature in the second range of temperatures is less than a maximum temperature in the first range of temperatures, forming a CMOS structure including a third thermal process having a third range of temperatures, wherein a maximum temperature in the third range of temperatures is less than a maximum temperature in the second range of temperatures, and forming at least one other part of the capacitor structure.Type: ApplicationFiled: August 24, 2022Publication date: February 29, 2024Inventors: Yoshitaka Nakamura, Yuanzhi Ma, Scott E. Sills, Si-Woo Lee, David K. Hwang
-
Publication number: 20240029899Abstract: Methods for forecasting case counts for a future date in one or more geographic areas of persons infected by a disease is disclosed. The presence of the disease in a biological sample is testable by a polymerase chain reaction (PCR) test. A load of one or more pathogens associated with the disease correlates with a PCR cycle which indicates presence of the one or more pathogens, and is referred to as a threshold cycle (Ct). Data relevant to forecasting the case counts including Ct data and other data is received. The Ct data comprises Ct values from PCR tests of biological samples from persons within the one or more geographic areas. Arrays of feature data for processing by a trained machine learning model are generated, comprising Ct features and other features obtained from the data. A forecasted number of infected persons are generated by processing the arrays using machine learning.Type: ApplicationFiled: July 21, 2023Publication date: January 25, 2024Applicant: Life Technologies CorporationInventors: Mahfuza Sharmin, Manimozhi Manivannan, David Woo, Imran Mujawar, Manoj Gandhi
-
Patent number: 11664090Abstract: A method of automatically sequencing or basecalling one or more DNA (deoxyribonucleic acid) molecules of a biological sample is described. The method comprises using a capillary electrophoresis genetic analyzer to measure the biological sample to obtain at least one input trace comprising digital data corresponding to fluorescence values for a plurality of scans. Scan labelling probabilities for the plurality of scans are generated using a trained artificial neural network comprising a plurality of layers including convolutional layers. A basecall sequence comprising a plurality of basecalls for the one or more DNA molecules based on the scan labelling probabilities for the plurality of scans is determined.Type: GrantFiled: June 11, 2020Date of Patent: May 30, 2023Assignee: Life Technologies CorporationInventors: Yong Chu, Stephanie Jo Schneider, Rylan Schaeffer, David Woo
-
Publication number: 20220013193Abstract: A deep basecaller system for Sanger sequencing and associated methods are provided. The methods use deep machine learning. A Deep Learning Model is used to determine scan labelling probabilities based on an analyzed trace. A Neural Network is trained to learn the optimal mapping function to minimize a Connectionist Temporal Classification (CTC) Loss function. The CTC function is used to calculate loss by matching a target sequence and predicted scan labelling probabilities. A Decoder generates a sequence with the maximum probability. A Basecall position finder using prefix beam search is used to walk through CTC labelling probabilities to find a scan range and then the scan a position of peak labelling probability within the scan range for each called base. Quality Value (QV) is determined using a feature vector calculated from CTC labelling probabilities as an index into a QV look-up table to find a quality score.Type: ApplicationFiled: December 10, 2019Publication date: January 13, 2022Inventors: Yong CHU, Stephanie SCHNEIDER, Rylan SCHAEFFER, David WOO
-
Publication number: 20210398615Abstract: A method of automatically sequencing or basecalling one or more DNA (deoxyribonucleic acid) molecules of a biological sample is described. The method comprises using a capillary electrophoresis genetic analyzer to measure the biological sample to obtain at least one input trace comprising digital data corresponding to fluorescence values for a plurality of scans. Scan labelling probabilities for the plurality of scans are generated using a trained artificial neural network comprising a plurality of layers including convolutional layers. A basecall sequence comprising a plurality of basecalls for the one or more DNA molecules based on the scan labelling probabilities for the plurality of scans is determined.Type: ApplicationFiled: June 11, 2020Publication date: December 23, 2021Applicant: Life Technologies CorporationInventors: Yong Chu, Stephanie Jo Schneider, Rylan Schaeffer, David Woo
-
Patent number: 10902593Abstract: A biological analysis system and an associated method are provided. The method is used for recovering off scale data in an image produced by a camera in a capillary electrophoresis instrument. The method comprises the steps of identifying bins of the image where electron counts exceed a maximum number of counts; setting an off-scale flag for the identified bins; and processing the image to obtain a recovered dye signal, based on the flag set for each bin, and using a dye matrix.Type: GrantFiled: August 30, 2019Date of Patent: January 26, 2021Assignee: Life Technologies CorporationInventors: Jeffrey Marks, David Woo, Wallace George
-
Patent number: 10648912Abstract: In one exemplary embodiment, a method for validating an instrument is provided. The method includes receiving amplification data from a validation plate to generate a plurality of amplification curves. The validation plate includes a sample of a first quantity and a second quantity, and each amplification curve includes an exponential region. The method further includes determining a set of fluorescence thresholds based on the exponential regions of the plurality of amplification curves and determining, for each fluorescence threshold of the set, a first set of cycle threshold (Ct) values of amplification curves generated from the samples of the first quantity and a second set of Ct values of amplification curves generated from the samples of the second quantity. The method includes calculating if the first and second quantities are sufficiently distinguishable based on Ct values at each of the plurality of fluorescence thresholds.Type: GrantFiled: February 5, 2016Date of Patent: May 12, 2020Assignee: Life Technologies CorporationInventors: Thomas Wessel, Yong Chu, Jacob Freudenthal, David Woo
-
Publication number: 20200074624Abstract: A biological analysis system and an associated method are provided. The method is used for recovering off scale data in an image produced by a camera in a capillary electrophoresis instrument. The method comprises the steps of identifying bins of the image where electron counts exceed a maximum number of counts; setting an off-scale flag for the identified bins; and processing the image to obtain a recovered dye signal, based on the flag set for each bin, and using a dye matrix.Type: ApplicationFiled: August 30, 2019Publication date: March 5, 2020Inventors: Jeffrey MARKS, David WOO, Wallace GEORGE
-
Patent number: 10557821Abstract: In one exemplary embodiment, a method for detecting variants in electropherogram data is provided. The method includes receiving electropherogram data from an instrument and analyzing the electropherogram data to identify mixed bases in the electropherogram data. The method further includes validating the identified mixed bases. Then the method includes determining variants in the electropherogram data based on the validated mixed bases.Type: GrantFiled: February 1, 2019Date of Patent: February 11, 2020Assignee: LIFE TECHNOLOGIES CORPORATIONInventors: David Denny, David Woo, Manjula Aliminati, Siva Kumar Samsani, Stephanie Schneider, Yoke Peng Lim, Sylvia Chang
-
Publication number: 20200003728Abstract: Embodiments implementing selected automated quality control operations in sample processing instruments that analyze dye-labeled samples are disclosed. In some embodiments, temperature and/or pressure parameters are measured and compared to thresholds to determine whether warning should be provided and/or actions taken. Embodiments for implementing automated correction of spectral error during the instrument's normal runtime operation without requiring the user to conduct a special, separate calibration run are also disclosed.Type: ApplicationFiled: February 16, 2018Publication date: January 2, 2020Applicant: Life Technologies CorporationInventors: Nivedita Majumdar, Wallace George, Jeffrey Marks, Ming Jiang, Sylvia Chang, David Woo
-
Publication number: 20190228053Abstract: The present teachings comprise systems and methods for calibrating the background or baseline signal in a PCR or other reaction. The background signal derived from detected emissions of sample wells can be subjected to a normalized statistical metric, and be compared to a threshold or other standard to discard outlier cycles or other extraneous data. According to various embodiments, a relative standard deviation (relativeSTD) for the background component can be generated by dividing the standard deviation by the median of differences across all wells, where the difference is defined as the difference between maximum and minimum pixel values of a well. The relativeSTD as a metric is not sensitive to machine-dependent variations in absolute signal output that can be caused by different gain settings, different LED draw currents, different optical paths, or other instrumental variations. More accurate background characterization can be achieved.Type: ApplicationFiled: January 28, 2019Publication date: July 25, 2019Inventors: Chengyong YANG, David WOO
-
Publication number: 20190170684Abstract: In one exemplary embodiment, a method for detecting variants in electropherogram data is provided. The method includes receiving electropherogram data from an instrument and analyzing the electropherogram data to identify mixed bases in the electropherogram data. The method further includes validating the identified mixed bases. Then the method includes determining variants in the electropherogram data based on the validated mixed bases.Type: ApplicationFiled: February 1, 2019Publication date: June 6, 2019Inventors: David DENNY, David WOO, Manjula ALIMINATI, Siva Kumar SAMSANI, Stephanie SCHNEIDER, Yoke Peng LIM, Sylvia CHANG
-
Publication number: 20190126281Abstract: A biological analysis system is provided. The system comprises a sample block assembly. The sample block assembly comprises a sample block configured to accommodate a sample holder, the sample holder configured to receive a plurality of samples. The system also comprises a control system configured to cycle the plurality of samples through a series of temperatures. The system further comprises an automated tray comprising a slide assembly, the tray configured to reversibly slide the sample block assembly from a closed to an open position to allow user access to the plurality of sample holders.Type: ApplicationFiled: August 29, 2018Publication date: May 2, 2019Inventors: Yong CHU, Jeffrey MARKS, Jacob FREUDENTHAL, Mingsong CHEN, Tiong Han TOH, Mauro AGUANNO, Lik Seng LAU, Lian Seng LOH, Kok Siong TEO, Zeng Wei CHU, Xin MATHERS, Michael UY, Huei Steven YEO, Kuan Moon BOO, Way Xuang LEE, Chin Yong KOO, Wei Fuh TEO, Soo Yong LAU, Hon Siu SHIN, Zeqi TAN, Thomas WESSEL, David WOO