Patents by Inventor David Zaccardelli

David Zaccardelli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Buffer solutions having selective bactericidal activity against gram negative bacteria and methods of using same
    Patent number: 9327031
    Abstract: Buffer solutions for pharmaceutical preparations that have bactericidal activity preferentially against gram negative bacteria are provided. The buffers have a pH of greater than about 10 or less than about 4.5 with low buffer capacity. Methods of their use in reducing the occurrence of blood stream infections in a mammal is also provided.
    Type: Grant
    Filed: January 17, 2014
    Date of Patent: May 3, 2016
    Assignee: United Therapeutics Corporation
    Inventors: Roger Andrew Jeffs, David Zaccardelli
  • STABLE SOLUTIONS OF TREPROSTINIL
    Publication number: 20140288179
    Abstract: An improved method for administering treprostinil or a salt is described that allows for use of the diluted solution prior to administration for a longer period of time to avoid wasted medication.
    Type: Application
    Filed: June 12, 2014
    Publication date: September 25, 2014
    Inventors: David Zaccardelli, Roger Andrew Jeffs
  • BUFFER SOLUTIONS HAVING SELECTIVE BACTERICIDAL ACTIVITY AGAINST GRAM NEGATIVE BACTERIA AND METHODS OF USING SAME
    Publication number: 20140194520
    Abstract: Buffer solutions for pharmaceutical preparations that have bactericidal activity preferentially against gram negative bacteria are provided. The buffers have a pH of greater than about 10 or less than about 4.5 with low buffer capacity. Methods of their use in reducing the occurrence of blood stream infections in a mammal is also provided.
    Type: Application
    Filed: January 17, 2014
    Publication date: July 10, 2014
    Applicant: United Therapeutics Corporation
    Inventors: Roger Andrew Jeffs, David Zaccardelli
  • Buffer solutions having selective bactericidal activity against gram negative bacteria and methods of using same
    Patent number: 8658694
    Abstract: Buffer solutions for pharmaceutical preparations that have bactericidal activity preferentially against gram negative bacteria are provided. The buffers have a pH of greater than about 10 or less than about 4.5 with low buffer capacity. Methods of their use in reducing the occurrence of blood stream infections in a mammal is also provided.
    Type: Grant
    Filed: February 7, 2011
    Date of Patent: February 25, 2014
    Assignee: United Therapeutics Corporation
    Inventors: Roger Andrew Jeffs, David Zaccardelli
  • Buffer solutions having selective bactericidal activity against gram negative bacteria and methods of using same
    Patent number: 8653137
    Abstract: Buffer solutions for pharmaceutical preparations that have bactericidal activity preferentially against gram negative bacteria are provided. The buffers have a pH of greater than about 10 or less than about 4.5 with low buffer capacity. Methods of their use in reducing the occurrence of blood stream infections in a mammal is also provided.
    Type: Grant
    Filed: June 7, 2013
    Date of Patent: February 18, 2014
    Assignee: United Therapeutics Corporation
    Inventors: Roger Andrew Jeffs, David Zaccardelli
  • BUFFER SOLUTIONS HAVING SELECTIVE BACTERICIDAL ACTIVITY AGAINST GRAM NEGATIVE BACTERIA AND METHODS OF USING SAME
    Publication number: 20130274340
    Abstract: Buffer solutions for pharmaceutical preparations that have bactericidal activity preferentially against gram negative bacteria are provided. The buffers have a pH of greater than about 10 or less than about 4.5 with low buffer capacity. Methods of their use in reducing the occurrence of blood stream infections in a mammal is also provided.
    Type: Application
    Filed: June 7, 2013
    Publication date: October 17, 2013
    Inventors: Roger Andrew Jeffs, David Zaccardelli
  • Buffer solutions having selective bactericidal activity against gram negative bacteria and methods of using same
    Patent number: 7999007
    Abstract: Buffer solutions for pharmaceutical preparations that have bactericidal activity preferentially against gram negative bacteria are provided. The buffers have a pH of greater than about 10 or less than about 4.5 with low buffer capacity. Methods of their use in reducing the occurrence of blood stream infections in a mammal is also provided.
    Type: Grant
    Filed: November 24, 2008
    Date of Patent: August 16, 2011
    Assignee: United Therapeutics Corporation
    Inventors: Roger Jeffs, David Zaccardelli
  • BUFFER SOLUTIONS HAVING SELECTIVE BACTERICIDAL ACTIVITY AGAINST GRAM NEGATIVE BACTERIA AND METHODS OF USING SAME
    Publication number: 20110144204
    Abstract: Buffer solutions for pharmaceutical preparations that have bactericidal activity preferentially against gram negative bacteria are provided. The buffers have a pH of greater than about 10 or less than about 4.5 with low buffer capacity. Methods of their use in reducing the occurrence of blood stream infections in a mammal is also provided.
    Type: Application
    Filed: February 7, 2011
    Publication date: June 16, 2011
    Inventors: Roger Jeffs, David Zaccardelli
  • BUFFER SOLUTIONS HAVING SELECTIVE BACTERICIDAL ACTIVITY AGAINST GRAM NEGATIVE BACTERIA AND METHODS OF USING SAME
    Publication number: 20090081319
    Abstract: Buffer solutions for pharmaceutical preparations that have bactericidal activity preferentially against gram negative bacteria are provided. The buffers have a pH of greater than about 10 or less than about 4.5 with low buffer capacity. Methods of their use in reducing the occurrence of blood stream infections in a mammal is also provided.
    Type: Application
    Filed: November 24, 2008
    Publication date: March 26, 2009
    Inventors: Roger Jeffs, David Zaccardelli