Abstract: A laundry care or dish care composition can include a poly alpha-1,6-glucan derivative, wherein the poly alpha-1,6-glucan derivative includes: (i) a poly alpha-1,6-glucan backbone of glucose monomer units, wherein greater than or equal to 40% of the glucose monomer units are linked via alpha-1,6 glycosidic linkages, and wherein from 0% to less than 30% of the glucose monomer units are linked via alpha-1,3 glycosidic linkages, and optionally at least 5% of the backbone glucose monomer units have branches via alpha-1,2 and/or alpha-1,3 glycosidic linkages; and (ii) at least one organic group linked to the poly alpha-1,6-glucan backbone through a linkage moiety; wherein, the poly alpha-1,6-glucan backbone has a weight average degree of polymerization of at least 5; and wherein, the poly alpha-1,6-glucan derivative has a degree of substitution of linkage moiety of from 0.20 to 1.00.

Abstract: The present invention is directed to inhibitors of the interaction of menin with MLL and MLL fusion proteins, pharmaceutical compositions containing the same, and their use in the treatment of cancer and other diseases mediated by the menin-MLL interaction.

Abstract: The present disclosure is directed to a reference voltage calibration. An apparatus includes a memory and a memory controller including a calibration circuit configured to perform a reference voltage calibration to determine a reference voltage used to distinguish between logic values read from the memory. The reference voltage calibration comprises performing horizontal calibrations at different reference voltage values to determine a range of delay values applied to a data strobe signal at which valid data is read from the memory. The calibration includes determining scores corresponding to ones of the plurality of horizontal calibrations in which a score for a particular one of the plurality of horizontal calibrations is based on a corresponding range of delay values and a reference voltage margin. Thereafter, the calibration circuit selects a calibrated reference voltage based on the scores corresponding to ones of the plurality of horizontal calibrations.

Abstract: Disclosed are a device, system, methods and computer-readable medium products that provide an updated insulin-to-carbohydrate ratio and an updated total daily insulin. The described processes may be used for periodic updating of the insulin-to-carbohydrate ratio and the total daily insulin. The insulin-to-carbohydrate ratio and/or the total may be used in the calculation of new doses of insulin that a drug delivery device may be commanded to deliver to a user.

Abstract: The invention relates to compounds of formula (I): or a salt thereof, wherein R1, G, L1, L2, L3, and Y are as described herein. Compounds of formula (I) and pharmaceutical compositions thereof are inhibitors of one, or both of, ?v?1 integrin and ?v?6 integrin that are useful for treating fibrosis such as in nonalcoholic steatohepatitis (NASH), idiopathic pulmonary fibrosis (IPF) and nonspecific interstitial pneumonia (NSIP).

Abstract: A switching power converter is provided that communicates with a mobile device to receive a value of a load detection current. The switching power converter adjusts the cycling of a power switch until a constant current mode of operation is entered with a known output current driving the mobile device. The switching power converter subtracts the load current from the output current to measure a soft-short circuit current.

Abstract: Example embodiments of the present disclosure relate to devices, methods, apparatuses and computer readable storage media for semi-static scheduling of multicast broadcast service traffic. In example embodiments, at least one of enabling, disabling or modification of a semi-persistent scheduling configuration is determined for a group of devices on a bandwidth part for multicast broadcast service traffic. The at least one of enabling, disabling or modification of the semi-persistent scheduling configuration is indicated to the group of devices.

Abstract: A neural network may be used to determine corner points of a skewed polygon (e.g., as displacement values to anchor box corner points) that accurately delineate a region in an image that defines a parking space. Further, the neural network may output confidence values predicting likelihoods that corner points of an anchor box correspond to an entrance to the parking spot. The confidence values may be used to select a subset of the corner points of the anchor box and/or skewed polygon in order to define the entrance to the parking spot. A minimum aggregate distance between corner points of a skewed polygon predicted using the CNN(s) and ground truth corner points of a parking spot may be used simplify a determination as to whether an anchor box should be used as a positive sample for training.

Abstract: The disclosure relates to modulating pyruvate kinase and provides novel chemical compounds useful as activators of PKR, as well as various uses of these compounds. PKR activating compounds are useful in the treatment of diseases and disorders associated with PKR and/or PKM2, such as pyruvate kinase deficiency (PKD), sickle cell disease (SCD), and thalassemia.

Abstract: The present invention relates to inhibitors of histone deacetylases, in particular HDAC8, that are useful for the treatment of cancer and other diseases and disorders, as well as the synthesis and applications of said inhibitors.

Abstract: A brushless direct-current (BLDC) motor is provided. The motor includes a stator including a stator core, stator teeth, and windings; a rotor shaft disposed within the stator and extending along a longitudinal axis; and a rotor. The rotor includes a rotor core including an inner body mounted on the rotor shaft and radial projections projecting outwardly from the inner body, a permanent magnet mounted on an outer end of the radial projections, and a mold structure formed in contact with the radial projections and configured to secure the permanent magnet to the rotor core.

Abstract: An apparatus and method for receiving a magnetic resonance (MR) signal for imaging a patient. The MR signal includes a MR frequency. A radio frequency (RF) coil has first and second end portions. An impedance converter is in electrical communication with the RF coil. A preamplifier in electrical communication with the impedance converter, the preamplifier having a gain. At least one resonant circuit electrically connected to at least one end portion of the RF coil.

Abstract: An apparatus and method for receiving a magnetic resonance (MR) signal for imaging a patient. The MR signal includes a MR frequency. A radio frequency (RF) coil has first and second end portions. An impedance converter is in electrical communication with the RF coil. A preamplifier in electrical communication with the impedance converter, the preamplifier having a gain. At least one resonant circuit electrically connected to at least one end portion of the RF coil.

Abstract: An apparatus and method for receiving a magnetic resonance (MR) signal for imaging a patient. The MR signal includes a MR frequency. A radio frequency (RF) coil has first and second end portions. An impedance converter is in electrical communication with the RF coil. A preamplifier in electrical communication with the impedance converter, the preamplifier having a gain. At least one resonant circuit electrically connected to at least one end portion of the RF coil.

Abstract: An uninterruptible power supply (UPS) system includes an enclosure and a plurality of power converter modules positioned in the enclosure, each power conversion module including a power converter circuit, a module controller circuit configured to control the power converter circuit and at least one module fan controlled by the module controller circuit. The system further includes a system controller positioned in the enclosure and configured to communicate with the module controller circuits over a communications bus and at least one exhaust fan configured to exhaust air from the enclosure and controlled by the system controller. The system controller is configured to control the at least one exhaust fan responsive to information, such as temperature and/or load information, received from the module controller circuits.

Abstract: A UPS circuit, comprising a rectification phase leg (PL1) for rectification, which is used for converting a received alternating current into a direct current; inversion phase legs (PL21, PL22, PL23) for inversion, which are used for inverting the direct current output by the rectification phase leg into an alternating current; a failure detection device (D) which is used for detecting whether an inversion phase leg has failed; a redundant inversion phase leg (PL2a), with an input end thereof being connected to an output end of the rectification phase leg; and a control device which is used for receiving a signal sent by the failure detection device and is also used for enabling the redundant inversion phase leg to replace the inversion phase leg which has failed when a failure occurs.

Abstract: A valve includes an inlet, an outlet, and a biasing element. The biasing element includes a first spring element, a second spring element, and a valve element. The second spring element includes at least one bimetallic disk including a first and second material. The first material includes a first coefficient of linear thermal expansion, and the second material includes a second coefficient of linear thermal expansion different than the first coefficient of linear thermal expansion. The valve element disposed on an end of the first spring element.

Abstract: The present invention provides a bidirectional DC-DC converter. The bidirectional DC-DC converter includes a first switching tube connected in antiparallel to a first diode; a second switching tube connected in antiparallel to a second diode; a third switching tube connected in antiparallel to a third diode; a fourth switching tube connected in antiparallel to a fourth diode; and a first inductor and a second inductor, where an anode of the first diode and a cathode of the second diode are connected to form a first node, an anode of the second diode and a cathode of the third diode are connected to a neutral point, an anode of the third diode and a cathode of the fourth diode are connected to form a second node, and one end of the first inductor and one end of the second inductor are respectively connected to the first node and the second node. The bidirectional DC-DC converter in the present invention has high conversion efficiency.

Abstract: Power control systems are provided including a digital controller configured to control gating mechanism for power switches responsive to an input from a power conversion circuit. The digital controller includes a conversion circuit, a modulation circuit and a gating control circuit. The system further includes an analog circuit comprising a filter, a current limiter and a compare circuit. The current limiter is configured to control a magnitude of a current pulled through a power convertor during a device switching operation.

Abstract: A gas turbine engine anti-icing system troubleshooting method comprising providing an anti-icing system comprising a bleed air source coupled to a pressure regulating valve set having an upper valve coupled end-to-end in series with a lower valve; and an air pressure sensor coupled to the pressure regulating valve set downstream of the pressure regulating valve set; detecting at least one valve fault; checking the upper valve for the at least one valve fault; checking the lower valve for the at least one valve fault; deactivating at least one of the upper valve and the lower valve; and replacing at least one of the upper valve and lower valve.