Abstract: Embodiments of the invention generally provide pharmaceutical drug compositions, methods of preparing oral drug compositions, such as extended release dosage compositions, and methods for treating antidepressant or smoking cessation. In one aspect, the invention provides a pharmaceutical formulation comprising a core, including bupropion and its salt derivatives, and a coating. The coating may include from about 5% to about 99% by weight of the coating of a pharmaceutically acceptable pH-independent polymer. The coating may further include from about 0.001% to about 30% by weight of the coating of a surfactant. In another aspect, the invention provides methods for preparing and administering a pharmaceutical composition in oral dosage form, such as a tablet.

Abstract: The present invention is directed to an apparatus for pre-assembly of an electrically connected array of solar panels for a solar canopy including a substantially planar base member for resting on a horizontal surface; a substantially planar support member; a track member disposed proximate a bottom portion of the support member attached to or integral with the support member or base member for vertically aligning side-by-side and vertically supporting a plurality of solar panels when a side edge portion of the solar panels rests on the track member; and at least two arm members, each having a free end and an attached end, the attached ends pivotally attached proximate to opposing ends of the base member or support member, the arm members being configured and adapted for removably attaching at least two solar panel support channels.

Abstract: Presented is a method of completing a subterranean well having an open wellbore extending through a subterranean formation having a target zone. In a preferred embodiment, a tubing assembly is placed in the wellbore, extending through the target zone. An annular space is defined between the outer surface of the tubing assembly and the wellbore wall. A gravel pack is placed in the annular space along at least a length of the target zone. Then an annular barrier forming material is flowed into the annular space along at least a length of the target zone. Then the annular barrier forming material is “set” to create an annular barrier in the annular space. The annular barrier forming material can be carried on the tubing assembly or pumped downhole. Flow restrictors, such as packers or a gravel pack, can be used to restrict flow of the annular barrier forming material to allow the material to set into an annular barrier.

Abstract: The present invention provides methods of generating a mammalian cell that is homozygous at a locus of interest, as well as cells made by the method. The present invention further provides methods of using the cells.

Abstract: A window or door system includes a frame adapted to be received within a window or door opening. A window or door unit is disposed on the frame, and a retainer is received by interference fit on either the frame or the window or door unit. The retainer has a portion that extends to engage the other of the frame and window or door unit, and to hold the window or door unit on the frame. The frame can be rectangular, for example, and the retainer may be linear extending along at least one edge of the frame. The frame can include an outwardly opening slot, and the retainer may be received by snap fit in the slot.

Abstract: An assembly that is adapted to position a track heater in spaced relation proximate to a surface of a track rail of a railroad. The assembly includes at least one heating element, and a hood or housing that is operable to at least partially surround the heating element while positioning the heating element near to track rail. The hood positions the heating element relative to the rail section such that a gap exists between the heating element and the rail section. As the heating element does not contact the rail, the heating element cannot form an electrical by-pass for signals passing through the rail section.

Abstract: Methods and apparatus to manipulate embroidery designs via a communication network are disclosed. The method includes receiving at a server, via the communication network, a request from a client computer, the request including first data associated with the embroidery design, processing at least some of the first data at the server to generate at least one of image data or embroidery data, and transmitting, via the communication network, a response to the client computer, the response to be received by a user interface for manipulating embroidery design information at the client computer and including at least one of the image data or the embroidery data.

Abstract: A novel maize variety designated PH1KD3 and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH1KD3 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH1KD3 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH1KD3 or a locus conversion of PH1KD3 with another maize variety.

Abstract: Methods and systems may provide for an image processing pipeline having a hardware module to spatially filter a raw image in the horizontal direction to obtain intermediate image data. The pipeline can also include a set of instructions which, if executed by a processor, cause the pipeline to spatially filter the intermediate image data in the vertical direction.

Abstract: Disclosed herein are polypeptides, polynucleotides encoding, cells and organisms comprising novel DNA-binding domains, including TALE DNA-binding domains. Also disclosed are methods of using these novel DNA-binding domains for modulation of gene expression and/or genomic editing of endogenous cellular sequences.

Abstract: Methods, systems, and apparatuses for down-converting and up-converting an electromagnetic signal. In embodiments, the invention operates by receiving an electromagnetic signal and recursively operating on approximate half cycles of a carrier signal. The recursive operations can be performed at a sub-harmonic rate of the carrier signal. The invention accumulates the results of the recursive operations and uses the accumulated results to form a down-converted signal. In embodiments, up-conversion is accomplished by controlling a switch with an oscillating signal, the frequency of the oscillating signal being selected as a sub-harmonic of the desired output frequency. When the invention is being used in the frequency modulation or phase modulation implementations, the oscillating signal is modulated by an information signal before it causes the switch to gate a bias signal. The output of the switch is filtered, and the desired harmonic is output.

Abstract: A mesh fixation system is disclosed including a plurality of elongate members and each elongate member includes a plurality of longitudinally extending support members. Each support member is connected to an adjacent support member by a plurality of connecting members and the elongate member defines at least one opening extending therethrough between adjacent support members and adjacent connecting members. The mesh fixation system further includes a plurality of legs extending from each support member. The plurality of legs is adapted for insertion through a mesh and into a body tissue to secure the mesh to the body tissue.

Abstract: A metamaterial for a radio frequency communications apparatus is disclosed. The metamaterial can comprise a flex circuit and an array of circuit elements mounted on the flex circuit. Each of the circuit elements can comprise a conductive trace and at least one hybrid component electrically coupled to the conductive trace.

Abstract: The present invention is directed to a refrigerator oil composition comprising (a) at least one diester species having the following structure: wherein R1, R2, R3, and R4 are the same or independently selected from hydrocarbon groups having from 2 to 17 carbon atoms; and (b) a refrigerant.

Abstract: This invention relates to genetic markers of mental illness, e.g., schizophrenia (SZ), and methods of use thereof.

Abstract: A variceal banding endoscope includes an elongated shaft having a distal end and a proximal end that is removably connected to a control unit. The endoscope includes a variceal banding apparatus fixedly attached to the distal end of the endoscope and capable of receiving a plurality of ligation bands. A trigger cable extends from the proximal end to the distal end of the shaft and is digitally actuated by an actuator in the control unit or handle of the scope in response to a user input device.

Abstract: In one aspect, the invention is related to a method of treating a patient with Parkinson's disease, the method including administering to the respiratory tract of the patient particles that include more than about 90 weight percent (wt %) of levodopa. The particles are delivered to the patient's pulmonary system, preferably to the alveoli or the deep lung.

Abstract: A Micro-Electro-Mechanical Systems (MEMS) interferometer is implemented in a Fourier transform spectrometer, which includes a common housing containing the interferometer and a gas cell, possibly including a preconcentrator. The interferometer system includes an optical bench and at least two mirror structures, being patterned from one or more layers on the optical bench and erected to extend substantially perpendicularly to the bench to define two interferometer arms to provide a MEMS interferometer.

Abstract: A computer system comprising a number of components which make up an infrastructure with the system having a Directory 10 and an APS which is adapted to centralize and automate information management for online service systems.