Patents by Inventor David

David has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GLP-1 receptor agonists and uses thereof
    Patent number: 12378230
    Abstract: Provided herein are 6-carboxylic acids of benzimidazoles and 4-aza-, 5-aza-, and 7-aza-benzimidazoles as GLP-1R agonists, processes to make said compounds, and methods comprising administering said compounds to a mammal in need thereof.
    Type: Grant
    Filed: October 9, 2023
    Date of Patent: August 5, 2025
    Assignee: Pfizer Inc.
    Inventors: Gary Erik Aspnes, Scott W. Bagley, John M. Curto, David James Edmonds, Mark E. Flanagan, Kentaro Futatsugi, David A. Griffith, Kim Huard, Yajing Lian, Chris Limberakis, Allyn T. Londregan, Alan M. Mathiowetz, David W. Piotrowski, Roger B. Ruggeri
  • Diazabicyclooctanones as inhibitors of serine ?-lactamases
    Patent number: 12378244
    Abstract: The invention relates to a compound which is a diazabicyclooctanone of Formula (I) or a pharmaceutically acceptable salt thereof: wherein R is as defined herein. The compounds are useful in the treatment of bacterial infection, in particular they are useful in reducing bacterial resistance to antibiotics. They are also useful in the treatment of bacteria which express serine-?-lactamase enzymes, in combination with antibiotics.
    Type: Grant
    Filed: November 15, 2023
    Date of Patent: August 5, 2025
    Assignee: Antabio SAS
    Inventors: Simon Leiris, David Thomas Davies
  • Process for preparing organotin compounds
    Patent number: 12378265
    Abstract: Provided is a facile process for preparing certain organotin compounds having alkyl and alkylamino substituents. The process provides organotin precursor compounds, for example tris(dimethylamido)isopropyl tin, in a highly pure form. As such, the products of the process are particularly useful in the deposition of high-purity tin oxide films in, for example, extreme ultraviolet light (EUV) lithography techniques used in microelectronic device manufacturing.
    Type: Grant
    Filed: May 23, 2023
    Date of Patent: August 5, 2025
    Assignee: ENTEGRIS, INC.
    Inventors: David Kuiper, David M. Ermert, Thomas Coyne
  • Lanthanide and lanthanide-like transition metal complexes
    Patent number: 12378273
    Abstract: The disclosed and claimed subject matter provides precursors having at least one tethered cyclopentadienyl ligand (“Cp ligand”), at least one amidinate ligand (“Ad ligand”) and a lanthanide and/or lanthanide-like transition metal (“M”) of the general formulae (i) (Cp ligand)2-M-(Ad ligand) or (ii) (Cp ligand)-M-(Ad ligand)2.
    Type: Grant
    Filed: November 18, 2021
    Date of Patent: August 5, 2025
    Assignees: Merck Patent GmbH, Versum Materials US, LLC
    Inventors: Christoph Wetzel, Holger Heil, Michal Krompiec, Lars Lietzau, David Bruge, Ming Fang, Sergei V. Ivanov
  • Chromium-free, iron-based catalyst for water gas shift reaction and methods of use thereof
    Patent number: 12378123
    Abstract: A chromium-free catalyst for use in a fluidized bed reactor is described. The catalyst comprises 45-70 wt % Fe2O3, 5-15 wt % CuO, 20-35 wt % Al2O3, 10-20 wt % ZnO, and 1-15 wt % K2CO3. The catalyst has a Davison Index (DI %) of less than or equal to 15. A method for converting carbon monoxide (CO) into carbon-dioxide (CO2) using the catalyst is described. The method includes introducing H2O and CO into a fluidized bed reactor having an operating temperature between about 375° C. and about 450° C. and comprising the chromium free catalyst. The CO conversion is at least 60%.
    Type: Grant
    Filed: April 22, 2020
    Date of Patent: August 5, 2025
    Assignee: Research Triangle Institute
    Inventors: Jian-Ping Shen, Brian Turk, Pradeepkumar Sharma, David Denton
  • Systems and methods for growth of intestinal cells in microfluidic devices
    Patent number: 12378528
    Abstract: Organs-on-chips are microfluidic devices for culturing living cells in micrometer sized chambers in order to model physiological functions of tissues and organs. Engineered patterning and continuous fluid flow in these devices has allowed culturing of intestinal cells bearing physiologically relevant features and sustained exposure to bacteria while maintaining cellular viability, thereby allowing study of inflammatory bowl diseases. However, existing intestinal cells do not possess all physiologically relevant subtypes, do not possess the repertoire of genetic variations, or allow for study of other important cellular actors such as immune cells. Use of iPSC-derived epithelium, including IBD patient-specific cells, allows for superior disease modeling by capturing the multi-faceted nature of the disease.
    Type: Grant
    Filed: April 4, 2024
    Date of Patent: August 5, 2025
    Assignees: EMULATE, INC., CEDARS-SINAI MEDICAL CENTER
    Inventors: S. Jordan Kerns, Norman Wen, Carol Lucchesi, Christopher David Hinojosa, Jacob Fraser, Jefferson Puerta, Geraldine Hamilton, Robert Barrett, Clive Svendsen, Daniel Levner, Stephen R. Targan, Michael Workman, Dhruv Sareen, Uthra Rajamani, Magdalena Kasendra
  • Reducing energy consumption in MEG reclamation
    Patent number: 12378177
    Abstract: A method is described herein, comprising vaporizing a glycol material by thermal contact with a heating medium to form a vaporized glycol stream, increasing a pressure of the vaporized glycol stream to form a pressurized glycol stream, and increasing a temperature of the heating medium by thermally contacting the heating medium with the pressurized glycol stream.
    Type: Grant
    Filed: December 1, 2020
    Date of Patent: August 5, 2025
    Assignee: CAMERON INTERNATIONAL CORPORATION
    Inventors: David John Knight, Steven Langley, Bryan Bussell
  • Variable frequency drive (VFD) surge detection and response
    Patent number: 12378971
    Abstract: A chiller system is provided and includes a compressor, a variable frequency drive (VFD) to drive the compressor at variable frequencies and a chiller controller to ascertain a chiller condition and to command the VFD to drive the compressor at one of the variable frequencies based on the chiller condition at a first sampling rate. The VFD is configured to drive the compressor at the one of the variable frequencies responsive to being commanded by the chiller controller, to ascertain the chiller condition at a second sampling rate, which is substantially higher than the first sampling rate, and to alert the chiller controller accordingly.
    Type: Grant
    Filed: December 16, 2022
    Date of Patent: August 5, 2025
    Assignee: CARRIER CORPORATION
    Inventors: David Ginsberg, Ismail Agirman
  • Ultrasonic device
    Patent number: 12379352
    Abstract: An ultrasonic device, the device comprising at least one flexible ultrasonic transducer; and a clamp configured to mount the at least one transducer to a test object. Optionally, the clamp may comprise one or more bands and wherein the one or more bands can optionally be metal or at least part of the one or more bands may be formed of a conformable material such that the one or more bands comprises a conformable band or band portion.
    Type: Grant
    Filed: February 27, 2020
    Date of Patent: August 5, 2025
    Assignee: NOVOSOUND LTD
    Inventors: David Hughes, Daniel Irving, Heather Trodden
  • Assays for fungal infection
    Patent number: 12378613
    Abstract: Methods and kits are described for testing for the presence or absence of any fungus in a sample. Examples of fungi that can be detected include, but are not limited to, those belonging to the genera Candida, Aspergillus and Pneumocystis. The methods include obtaining a sample suspected of containing fungal nucleic acid, including at least one universal region of fungal nucleic acid, and testing for the presence or absence in the sample of the at least one universal region of fungal nucleic acid. Samples may be biological or non-biological.
    Type: Grant
    Filed: January 24, 2024
    Date of Patent: August 5, 2025
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Steven Park, David S. Perlin, David W. Denning
  • Technique to perform demodulation of wireless communications signal data
    Patent number: 12381763
    Abstract: Apparatuses, systems, and techniques to demodulate data for fifth-generation (5G) new radio (NR). In at least one embodiment, a processor includes one or more circuits to use a parallel processor to determine a signal value based, at least in part, on one or more predetermined probability values.
    Type: Grant
    Filed: February 16, 2021
    Date of Patent: August 5, 2025
    Assignee: NVIDIA Corporation
    Inventor: Jeremy David Furtek
  • Decoupling capacitor inside gate cut trench
    Patent number: 12382621
    Abstract: An approach to forming a semiconductor device where the semiconductor device includes a first power rail that is connected to a decoupling capacitor by way of a first gate. The decoupling capacitor is also connected to a second gate. As such, the decoupling capacitor separates the first gate from the second gate. The decoupling capacitor may include a dielectric liner within a gate cut trench and a ferroelectric material over the dielectric liner. A second power rail may be connected to the decoupling capacitor by way of the second gate. The first gate and the second gate may be inline with respect thereto.
    Type: Grant
    Filed: June 22, 2022
    Date of Patent: August 5, 2025
    Assignee: International Business Machines Corporation
    Inventors: Reinaldo Vega, Takashi Ando, Praneet Adusumilli, David Wolpert, Cheng Chi
  • Chimeric protein toxins for expression by therapeutic bacteria
    Patent number: 12378536
    Abstract: Bacteria with tumor-targeting capability express, surface displayed, secreted and/or released modified chimeric therapeutic proteins with enhanced therapeutic activity against a neoplastic tissue including solid tumors, lymphomas and leukemias. The bacteria may be attenuated, non-pathogenic, low pathogenic or a probiotic. The chimeric proteins may be protease sensitive and may optionally be further accompanied by co-expression of a secreted protease inhibitor as a separate molecule or as a fusion.
    Type: Grant
    Filed: June 8, 2020
    Date of Patent: August 5, 2025
    Inventor: David Gordon Bermudes
  • Galvannealed steel sheet
    Patent number: 12378627
    Abstract: A galvannealed steel sheet obtainable by a method including the provision of a specific steel sheet, a recrystallization annealing with specific heating, soaking and cooling sub-steps using an inert gas, a hot-dip galvanizing and an alloying treatment, wherein the zinc coating is alloyed through diffusion of the iron from the steel sheet such that the zinc coating includes from 5 to 15% by weight of Fe, oxides including FeO, Mn2SiO4 and MnO, the balance being zinc, the steel sheet including internal oxides including FeO, Mn2SiO4 and MnO in the steel sheet.
    Type: Grant
    Filed: December 13, 2023
    Date of Patent: August 5, 2025
    Assignee: ArcelorMittal
    Inventors: David Zapico Alvarez, Florence Bertrand, Joris Giroux
  • Universal dynamic athletic ankle brace and add-on interior stirrup support system
    Patent number: 12376981
    Abstract: A rear-entry ankle brace includes an elastomeric component defining an inside elbow channel configured to span an ankle joint. A channel opening extends the length of the elastomeric component for direct insertion on top of a leg. One or more leg straps are used to adjustably tension first and second rear edges of the channel opening toward one another and secure the brace to the lower leg. Two foot straps are used to adjustably tension first and second bottom edges of the channel opening toward one another and secure the brace to the mid-foot. The foot straps overlap on the bottom to define a plantar surface of the brace and cross over each other on the topside of the elastomeric component and are secured to a leg strap. A pair of stabilizing stirrups optionally are included on the inside surfaces of the elastomeric component and receive the malleoli.
    Type: Grant
    Filed: May 2, 2024
    Date of Patent: August 5, 2025
    Assignee: RUBBER CITY BRACING COMPANY LLC
    Inventors: Annunziato Amendola, Anthony Perera, Bryan Den Hartog, David B. Kay, Nicholas Gomez, Ian D. Kovacevich, Nouphone J. Bansasine
  • Anti-rollout assemblies and systems for cargo handling system
    Patent number: 12377770
    Abstract: An anti-rollout assembly may comprise: a housing defining a cavity; a guide/restraint head pivotably coupled to the housing at a first end of the cavity; an overridable trigger pivotably coupled to the housing at a second end of the cavity, the second end opposite the first end; and a locking system operably coupled to the guide/restraint head and the overridable trigger, the locking system configured to bias the guide/restraint head into an upright position, the locking system configured to retract the guide/restraint head into the cavity in response to a first lateral force driving the overridable trigger. The locking system may comprise a drive link and a locking link and be configured to lock the guide/restraint head in a raised state.
    Type: Grant
    Filed: June 3, 2024
    Date of Patent: August 5, 2025
    Assignee: Goodrich Corporation
    Inventors: Brandon Lee, Wallace Harold Larson, Michael David Schuh
  • Center camera mirror system spoiler mounting for vehicle, and tailgate assembly including same
    Patent number: 12377793
    Abstract: A center camera mirror system spoiler mounting for a vehicle that can include a spoiler inner panel, a spoiler outer panel and a camera assembly. The spoiler inner panel can be configured to be mounted onto an exterior panel of the vehicle and the spoiler outer panel can be connected to the spoiler inner panel. The spoiler outer panel can include an outer surface that is an exterior surface of the vehicle, a camera opening passing through the spoiler outer panel, and a first datum. The camera assembly can be fixed to the spoiler inner panel in a predetermined orientation with respect to the spoiler inner panel, and can include a lens, and a second datum engaging the first datum. The lens can be in a predetermined alignment with respect to the camera opening when the second datum engages the first datum.
    Type: Grant
    Filed: August 16, 2023
    Date of Patent: August 5, 2025
    Assignee: HONDA MOTOR CO., LTD.
    Inventors: Timothy Lamprey, Jason Scott Borland, Jesse W. Schlabach, Hirofumi Takemoto, David J. Rose, Timothy J. Rupp, Douglas R. Kaltenmark
  • Aerosol generation
    Patent number: 12376623
    Abstract: A device for generating an inhalable medium, the device comprising: a container retaining a first volatilizable material, the material having a pH of greater than 7; a heater for volatilising the first volatilizable material held in the container; a chamber containing aerosolizable material comprising nicotine; and an outlet; the arrangement being such that in use, the first volatilizable material is volatilized by the heater to form a vapor and/or an aerosol, which passes through the chamber containing aerosolizable material and entrains one or more constituents of the aerosolizable material, thereby forming an inhalable medium which passes through the outlet.
    Type: Grant
    Filed: December 20, 2019
    Date of Patent: August 5, 2025
    Assignee: NICOVENTURES TRADING LIMITED
    Inventors: Walid Abi Aoun, David Bishop
  • Wheeled cart
    Patent number: D1086691
    Type: Grant
    Filed: October 28, 2021
    Date of Patent: August 5, 2025
    Assignee: Amazon Technologies, Inc.
    Inventors: Robert P. Irwin, Matthew Clark Webster, Robert David Serra, Wade Burch, Jacob Paul Warren
  • Electronic device
    Patent number: D1087066
    Type: Grant
    Filed: May 3, 2024
    Date of Patent: August 5, 2025
    Assignee: Amazon Technologies, Inc.
    Inventors: Michael Edward James Paterson, Giles David Matthew McWilliam