Abstract: This application relates to compounds of Formula (I): or pharmaceutically acceptable salts thereof, which are inhibitors of PI3K-? which are useful for the treatment of disorders such as autoimmune diseases, cancer, cardiovascular diseases, and neurodegenerative diseases.

Abstract: A Global Navigation Satellite System (GNSS) receiver demodulates code shift keying (CSK) data utilizing a binary search. The GNSS receiver receives a signal including a pseudorandom noise (PRN) code modulated by code shift keying (CSK) to represent a symbol (i.e., CSK modulated symbol). The GNSS receiver maintains a plurality of receiver codes each representing a different shift in chips to the PRN code. The GNSS receiver performs a linear combination of portions of the receiver codes. In an embodiment, the GNSS receiver compares correlation power level value for respective portions of the receiver codes to demodulate the CSK data. In a further embodiment, the GNSS receiver compares the correlation power level values for portions of receiver codes with power detection threshold values to demodulate the CSK data. In a further embodiment, the GNSS receiver utilizes signs of the correlation power level values to demodulate the CSK data.

Abstract: A synthetic representation of a robot tool for display on a user interface of a robotic system. The synthetic representation may be used to show the position of a view volume of an image capture device with respect to the robot. The synthetic representation may also be used to find a tool that is outside of the field of view, to display range of motion limits for a tool, to remotely communicate information about the robot, and to detect collisions.

Abstract: An electrical motor comprising multiple inductive coils, and a method for using same, is disclosed. The inductive coils may be configured to conduct current bi-directionally. Terminals of the inductive coils may be coupled to a common node on a power bus coupled to a power supply. Current flowing in a first inductive coil from the power bus may be largely offset by current returned to the power bus from a second inductive coil.

Abstract: Embodiments of a system and method of this disclosure continually determine a mass balance of a drilling or circulating system, using mass flow and density data adjusted for temperature and pressure. The system and method may be used to continually monitor and control wellbore pressures to achieve over-balanced managed pressure drilling (“MPD”). In some embodiments, the system and method may be used as a fluid tracking engine. In other embodiments, the system and method may be used to accurately track a fluid caliper intended to survey the well to determine string volumes or borehole volumes; an example is determining the volume of cement needed to circulate the cement or bring the cement up to desired height. The system and method may be used to track the effects of mixing. The system and method may also be used as a viscometer.

Abstract: A device for bubbling a gas into a liquid is disclosed. The device comprises a first bubbling apparatus nested inside a second bubbling apparatus. The first bubbling apparatus comprises a gas inlet for receiving the gas and a plurality of first openings for releasing the gas. The second bubbling apparatus at least partially encloses the plurality of first openings of the first bubbling apparatus. The second bubbling apparatus receives the gas from the plurality of first openings. The second bubbling apparatus comprises a plurality of second openings for bubbling the gas into the liquid.

Abstract: Embodiments that generate multiple haptic effects receive a first haptic effect signal having a first priority and corresponding to a first haptic effect, and receive a second haptic effect signal having a second priority and corresponding to a second haptic effect. When the first priority is less than the second priority, embodiments generate an interaction parameter using the second haptic effect signal. When the second priority is less than the first priority, embodiments generate the interaction parameter using the first haptic effect signal. Embodiments then apply a drive signal to a haptic output device according to the interaction parameter, where the drive signal causes the first haptic effect and the second haptic effect to be generated by the haptic output device concurrently.

Abstract: A method, a system and computer program products for securely enabling in-network functionality over encrypted data sessions, the method involving establishing an encrypted data session between a client communication application (100) and a server communication application (200) over a communication network; receiving and/or transmitting, by the client communication application (100), in the established encrypted data session, at least one encrypted communication data (D) from/to the server communication application (200) through a computing network element (M); and performing, by the computing network element (M), different actions other than data packet forwarding from one communication application to the other on the encrypted communication data (D). The encrypted communication data (D) has a plurality of data portions, or contexts, (CTX), each encrypted by a context key, and the different actions being specific for the computing network element (M) and for one or more of the contexts (CTX_X).

Abstract: A method and system hosts a game on a collaboration platform to allow playing users to participate in gameplay of the game. The method and system identify a condition of the game that is specified by the creating user of the game and identifies first social interaction criteria for the plurality of playing user. Satisfaction of the condition qualities at least one of the playing users to receive a friend request. The method and system determine that a first social interaction between a first playing user and a second playing user of the plurality of playing users playing the game satisfies the condition of the game. The method and system send the friend request to a first client device of the first playing user inviting the first playing user to establish a friendship with the second playing user on the collaboration platform.

Abstract: The invention relates to an isolated immunoglobulin heavy chain polypeptide and an isolated immunoglobulin light chain polypeptide that bind to a programmed death-1 (PD-1) protein. The invention provides a PD-1-binding agent that comprises the aforementioned immunoglobulin heavy chain polypeptide and immunoglobulin light chain polypeptide. The invention also provides related vectors, compositions, and methods of using the PD-1-binding agent to treat a cancer or an infectious disease.

Abstract: A connecting rod for a variable compression internal combustion engine, the connecting rod including an eccentrical element adjust arrangement for adjusting an effective connecting rod length, wherein an adjustment travel of the eccentrical element adjustment arrangement is adjustable by a switch valve, and wherein a valve housing of the switch valve is axially secured in a borehole of the connecting rod.

Abstract: A modular passive RF apparatus includes a passive RF portal and a passive RF expansion module configured to be removably coupled with the passive RF portal. A male connector is configured to extend from a top surface of the passive RF portal, and a female connector is configured to extend from the first end wall of the passive RF expansion portal. The female connector is configured to slidingly engage the male connector in a direction parallel to the top surface of the passive RF portal in order to mechanically couple the passive RF expansion module with the passive RF portal, and the male connector is configured to prevent the female connector from being removed from the male connector in a direction perpendicular to the top surface of the passive RF portal.

Abstract: A technique employs a system and methodology for improving sand control in pumps. The technique may be used in centrifugal pumps by providing uniquely constructed rib feature to facilitate sand control and thus reduction of erosion due to sand in the pumped fluid. The improved sand control is useful in centrifugal pumps employed in a variety of oilfield applications, such as in electric submersible pumping systems positioned downhole in a wellbore to pump oil or other fluids. The rib feature may be used in combination with a shield and arranged along diffuser bowl walls or other diffuser walls within sequential pump stages.

Abstract: A Global Navigation Satellite System (GNSS) receiver demodulates code shift keying (CSK) data utilizing correlations with combinational pseudo-random noise (PRN) codes generated for different bit positions. The GNSS receiver receives a signal including a PRN code modulated by CSK to represent a symbol (i.e., CSK modulated symbol). The GNSS receiver maintains a plurality of receiver codes, each representing a different shift in chips to the PRN code. The GNSS receiver performs a chip-by-chip linear combination of a group of receiver codes for each bit position of the CSK modulated symbol. The GNSS receiver correlates the received signal with each combinational PRN code to produce a binary value that is the CSK modulated symbol.

Abstract: In some embodiments, the present invention provides for a computer system which includes at least the following components: a plurality of computing devices associated with a plurality of users associated with a plurality of users; where each computing device of the plurality of computing devices is configured to: electronically receive software which, when being executed, cause such computing device to display a plurality of instances of a specifically programmed graphical user interface (GUI); where each instance of the GUI is configured to display a real-time updatable meeting information representative of a direct electronic proximity-based communication between at least two computing devices associated with at least two users who desire to meet at a particular location to engage in a transaction of at least one good, at least one service, or both, whose marketable value lasts for a period of 30 seconds to 60 minutes.

Abstract: Described herein are compositions and compounds having one or more aziridinyl groups, and methods of making the same. The compounds can also have one or more nitrogen atoms that each can be positively charged. The composition and compounds can inactivate one or more nucleic acid molecules (e.g. a DNA and/or a RNA from a pathogen) in a sample. The sample can comprise a blood or blood product (e.g., donated blood). The compositions and compounds can inactivate any nucleic acid present in a blood or blood product, thereby making the blood or blood product safe for use (e.g., in a transfusion).

Abstract: Methods and systems for network devices are provided. One method includes receiving a frame by a network device communicating with a computing device via a peripheral link, the network device receiving the frame via a network connection; using one or more frame header fields to generate a frame context by the network device; determining if a processor of the network device is processing another frame with the same frame context; assigning the frame context to a first processor of the network device, when the first processor is processing the other frame with the same frame context; and when neither processor is processing the same frame context, selecting between the first processor and a second processor of the network device, based on a workload of the first processor and the second processor, the workload determined by a number of contexts that are pending for the first processor and the second processor.

Abstract: A multi-layer software controlled antenna. A radiating patch is provided over a variable dielectric constant (VDC) plate. Variable DC potential is applied across the VDC plate to control the effective dielectric constant at various locations of the VDC plate. RF signal is coupled between a feed patch and a delay line, and the delay line couples the RF signal to the radiating patch. The radiating patch, VDC plate, delay line, and feed patch are each provided at a different layer of the antenna, so as to decouple the RF and DC signal paths. A controller executes a software program to thereby control the variable DC potential applied across the VDC plate, thereby controlling the operational characteristics of the antenna.

Abstract: An ultrasonic diagnostic imaging system is gated to acquire images at different phases of a physiological cycle such as the heartbeat. At each successive heart cycle a trigger actuates the acquisition of a continuous sequence of images, starting at a particular phase of the heart cycle and ending when the next heart cycle begins. Multiple triggers are used, each starting at a different phase of the heart cycle and each acquiring images at uniform temporal spacing. After the first trigger is used a sequence of images has been captured which are temporally evenly spaced over the heart cycle, and as successive triggers are used uniform temporal spacing is maintained as the heart cycle is filled in with additional images for replay of an image loop of phase re-ordered images at a high frame rate of display.

Abstract: Disclosed are compositions and methods for their use that include a combination of hydrolyzed algin, escin, Ruscus aculeatus root extract, ammonium glycyrrhizate, Centella asiatica extract, hydrolyzed yeast protein, and Calendula officinalis flower extract.