Abstract: The invention relates to antibodies and binding fragments thereof that are capable of binding to influenza A virus hemagglutinin and neutralizing at least one group 1 subtype and at least 1 group 2 subtype of influenza A virus. In one embodiment, an antibody or binding fragment according to the invention is capable of binding to and/or neutralizing one or more influenza A virus group 1 subtypes selected from H1, H2, H5, H6, H8, H9, H11, H12, H13, H16 and H17 and variants thereof and one or more influenza A virus group 2 subtype selected from H3, H4, H7, H1, 0, H14 and H15 and variants thereof.

Abstract: The invention relates to antibodies, and antigen binding fragments thereof, that neutralize infection of both group A and group B RSV. The invention also relates to antigenic sites to which the antibodies and antigen binding fragments bind, as well as to nucleic acids that encode and immortalized B cells and cultured plasma cells that produce such antibodies and antibody fragments. In addition, the invention relates to the use of the antibodies, antibody fragments, and polypeptides recognized by the antibodies of the invention in screening methods as well as in the diagnosis, treatment and prevention of RSV infection and group A and group B RSV co-infection.

Abstract: The invention relates to methods of generating a robust passive and an active immune response in a subject comprising administering a neutralizing antibody and a pathogen to the subject. The invention also relates to kits and pharmaceutical compositions useful in generating a robust passive and an active immune response in a subject.

Abstract: A medium voltage switch unit comprising an interruption unit and a disconnection unit, wherein the interruption unit comprises a first and a second interruption contact and a first drive unit which moves one of said interruption contacts between a first position in which they are in electrical connection and a second position in which they are spaced apart. The disconnection unit comprises a first and a second fixed disconnection contacts couplable and uncouplable with respective first and second movable disconnection contacts mounted on the interruption unit and electrically connected to the first interruption contact. The interruption unit is mechanically supported by a first fixed conductor and the second interruption contact is electrically connected to said first fixed conductor.

Abstract: A three-positions disconnector comprising, for each phase an insulating casing which comprises a first and a second cavity separated by an insulated partition wall, a through hole being present in said partition wall between said first and second cavity. The first cavity houses: a first fixed contact electrically connected to a corresponding branch conductor (of a bus-bar system; at least a portion of a movable contact pivotally mounted on a support positioned in the first cavity and electrically connected to a first electrical terminal positioned in said second cavity. The disconnector further comprises, for each phase, a second fixed contact suitable for ground connection.

Abstract: The invention relates to antibodies and antigen binding fragments thereof that neutralize HIV-1 infection. The invention also relates to nucleic acids that encode, immortalized B cells and cultured plasma cells that produce, and to epitopes that bind to such antibodies and antibody fragments. In addition, the invention relates to the use of the antibodies, antibody fragments, and epitopes in screening methods as well as in the diagnosis, treatment and prevention of HIV-1 infection.

Abstract: A partitioning device for Medium Voltage cubicles which comprises at least a fixed partition wall and at least a movable partition shutter. The partition shutter is capable to be moved between a first, closed, position and a second, open, position. The partitioning device further comprises an actuating device which is operatively connected to said partition shutter and capable to be operatively interfaced to a Medium Voltage circuit breaker and further capable to be actuated by a movement of said Medium Voltage circuit breaker during an insertion/extraction operation of said circuit breaker.

Abstract: A medium voltage switch unit comprising an interruption unit and a disconnection unit, wherein the interruption unit comprises a first and a second interruption contact and a first drive unit which moves one of said interruption contacts between a first position in which they are in electrical connection and a second position in which they are spaced apart. The disconnection unit comprises a first and a second fixed disconnection contacts couplable and uncouplable with respective first and second movable disconnection contacts mounted on the interruption unit and electrically connected to the first interruption contact. The interruption unit is mechanically supported by a first fixed conductor and the second interruption contact is electrically connected to said first fixed conductor.

Abstract: A three-positions disconnector comprising, for each phase an insulating casing which comprises a first and a second cavity separated by an insulated partition wall, a through hole being present in said partition wall between said first and second cavity. The first cavity houses: a first fixed contact electrically connected to a corresponding branch conductor (of a bus-bar system; at least a portion of a movable contact pivotally mounted on a support positioned in the first cavity and electrically connected to a first electrical terminal positioned in said second cavity. The disconnector further comprises, for each phase, a second fixed contact suitable for ground connection.

Abstract: An earthing switch for a medium voltage switchgear comprising a plurality of fixed contacts, a plurality of movable contact surfaces which are suitable to contact said plurality of fixed contacts and a support structure suitable to support moving means which allow the movement of said second plurality of contact surfaces. The earthing switch comprises at least one guide which comprises a fixed element and a moving element coaxially coupled therewith, said moving element being operatively connected to said movable contact surfaces so as to allow their movement along a substantially rectilinear direction from a first position, corresponding to an open condition of said switch, to a second position corresponding to a closed condition of said switch.

Abstract: An earthing switch for a medium voltage switchgear comprising a plurality of fixed contacts, a plurality of movable contact surfaces which are suitable to contact said plurality of fixed contacts and a support structure suitable to support moving means which allow the movement of said second plurality of contact surfaces. The earthing switch comprises at least one guide which comprises a fixed element and a moving element coaxially coupled therewith, said moving element being operatively connected to said movable contact surfaces so as to allow their movement along a substantially rectilinear direction from a first position, corresponding to an open condition of said switch, to a second position corresponding to a closed condition of said switch.