Patents by Inventor Davide Moscatelli

Davide Moscatelli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12281256
    Abstract: A treatment fluid may be suitable for a hydrocarbon fluid extraction well. Such a treatment fluid may include a water-in-oil emulsion. The water-in-oil emulsion may include: an oily continuous phase; and an aqueous discontinuous phase comprising water and a plurality of particles comprising a hydrogel comprising a cationic polymer. The cationic polymer may include, in polymerized form, a monomer with one or more cationic groups. The cationic group may be a —N+—R1R2R3 group, wherein R1, R2, and R3, are independently H or a C1 to C4 alkyl group.
    Type: Grant
    Filed: September 27, 2023
    Date of Patent: April 22, 2025
    Assignee: ENI S.P.A.
    Inventors: Davide Moscatelli, Lucilla Del Gaudio, Paola Albonico, Alessandra Belloni, Alberto Cesana
  • Publication number: 20250049839
    Abstract: The present invention provides compositions and methods for targeting cells for therapeutic and/or diagnostic purposes, e.g., delivery of therapeutic and/or diagnostic agents to a cell. Nanoparticles and polymers functionalized with capture molecules, reporter molecules, and/or therapeutic agents are provided for the treatment or prevention of disease, including neurological diseases associated with neuroinflammation, and cancer.
    Type: Application
    Filed: October 31, 2024
    Publication date: February 13, 2025
    Applicants: Children's Medical Center Corporation, Politecnico di Milano, Dana-Farber Cancer Institute, Inc.
    Inventors: Marco Peviani, Alessandra Biffi, Davide Moscatelli, Umberto Capasso Palmiero, Renato Auriemma, Mattia Sponchioni, Letterio Salvatore Politi
  • Patent number: 12161663
    Abstract: The present invention provides compositions and methods for targeting cells for therapeutic and/or diagnostic purposes, e.g., delivery of therapeutic and/or diagnostic agents to a cell. Nanoparticles and polymers functionalized with capture molecules, reporter molecules, and/or therapeutic agents are provided for the treatment or prevention of disease, including neurological diseases associated with neuroinflammation, and cancer.
    Type: Grant
    Filed: September 28, 2020
    Date of Patent: December 10, 2024
    Assignees: Children's Medical Center Corporation, Politecnico di Milano, Dana-Farber Cancer Institute, Inc.
    Inventors: Marco Peviani, Alessandra Biffi, Davide Moscatelli, Umberto Capasso Palmiero, Renato Auriemma, Mattia Sponchioni, Letterio Salvatore Politi
  • Publication number: 20240279425
    Abstract: Industrial depolymerization process of polyethylene terephthalate (PET) contained in artificial, natural and mixed dimethyl terephthalate (DMT) fibres by a first depolymerization of the PET in the presence of ethylene glycol and a catalyst (preferably sodium carbonate) to bis hydroxyethylene terephthalate (BHET), and subsequent transesterification of BHET solutions from the pressing of said artificial or natural fibres and from the washing of the same fibres. This process is characterized in that: in step a) the weight ratio of PET-containing fibres to ethylene glycol is between 0.3 and 4, preferably between 1.2 and 1.5; step b) comprises a step b-1) of pressing the final mixture and a step b-2) of washing the fibres from b1) with methanol or with the post-crystallization recovery solution of DMT, and in step c) the transesterification is carried out on the BHET liquid solution from the pressing b-1) and on that also containing methanol from washing the fibres of step b-2).
    Type: Application
    Filed: July 13, 2022
    Publication date: August 22, 2024
    Inventors: Davide MOSCATELLI, Giuseppe STORTI, Flavio TOLLINI, Gianmarco POLOTTI, Lorenzo BRIVIO, Paolo INNOCENTI
  • Publication number: 20240269169
    Abstract: The present invention provides compositions and methods for the treatment or prevention of a neurological disease or disorder of the central nervous system (e.g., a storage disorder, lysosomal storage disorder, neurodegenerative disease, etc.) by reconstitution of brain myeloid cell and microglia upon transplantation of hematopoietic cells enriched in microglia reconstitution potential. The invention also provides compositions and methods for ablating and reconstituting microglia.
    Type: Application
    Filed: December 29, 2023
    Publication date: August 15, 2024
    Applicants: The Children's Medical Center Corporation, Ospedale San Raffaele S.r.l., Politecnico di Milano, Fondazione Telethon ETS, Dana-Farber Cancer Institute, Inc.
    Inventors: Alessandra BIFFI, Marco PEVIANI, Davide MOSCATELLI, Alessia CAPOTONDO, Rita MILAZZO, Umberto CAPASSO PALMIERO
  • Publication number: 20240262975
    Abstract: Method for recovering polyesters and polyamides from the corresponding polymeric waste products, comprising the following steps: a) Depolymerization of the polyester/polyamide and obtaining the linear and/or cyclic oligomers and/or monomers, b) Recovery and purification of the products from step a), c) Polymerization of the product from step b) by polycondensation and/or ring opening polymerization. In step a) the depolymerization is partial and results in a mixture of oligomers, comprising especially cyclic oligomers and said step is conducted in a polar and/or apolar aprotic solvent at the temperature near solvent boiling temperature, between 100 and 300° C. and in the presence of a catalyst, simultaneously distilling the reaction solvent and the volatile by-products dissolved therein.
    Type: Application
    Filed: June 7, 2022
    Publication date: August 8, 2024
    Inventors: Flavio TOLLINI, Massimo MORBIDELLI, Giuseppe STORTI, Davide MOSCATELLI
  • Patent number: 11957713
    Abstract: The present invention provides compositions and methods for the treatment or prevention of a neurological disease or disorder of the central nervous system (e.g., a storage disorder, lysosomal storage disorder, neurodegenerative disease, etc.) by reconstitution of brain myeloid cell and microglia upon transplantation of hematopoietic cells enriched in microglia reconstitution potential. The invention also provides compositions and methods for ablating and reconstituting microglia.
    Type: Grant
    Filed: October 16, 2017
    Date of Patent: April 16, 2024
    Assignees: CHILDREN'S MEDICAL CENTER CORPORATION, OSPEDALE SAN RAFFAELE S.R.L., POLITECNICO DI MILANO, FONDAZIONE TELETHON ETS, DANA-FARBER CANCER INSTITUTE, INC
    Inventors: Alessandra Biffi, Marco Peviani, Davide Moscatelli, Alessia Capotondo, Rita Milazzo, Umberto Capasso Palmiero
  • Publication number: 20240026210
    Abstract: A treatment fluid may be suitable for a hydrocarbon fluid extraction well. Such a treatment fluid may include a water-in-oil emulsion. The water-in-oil emulsion may include: an oily continuous phase; and an aqueous discontinuous phase comprising water and a plurality of particles comprising a hydrogel comprising a cationic polymer. The cationic polymer may include, in polymerized form, a monomer with one or more cationic groups. The cationic group may be a —N+—R1R2R3 group, wherein R1, R2, and R3, are independently H or a C1 to C4 alkyl group.
    Type: Application
    Filed: September 27, 2023
    Publication date: January 25, 2024
    Applicant: ENI S.P.A.
    Inventors: Davide MOSCATELLI, Lucilla DEL GAUDIO, Paola ALBONICO, Alessandra BELLONI, Alberto CESANA
  • Patent number: 11859125
    Abstract: A method for inhibiting water permeation in an extraction well of a hydrocarbon fluid from an underground reservoir may include: supplying a water-in-oil emulsion including an oily continuous phase and an aqueous discontinuous phase containing a plurality of particles of at least one hydrogel containing a cationic polymer; and positioning the water-in-oil emulsion in contact with the underground reservoir. A treatment fluid for hydrocarbon fluid extraction wells may contain a water-in-oil emulsion including an oily continuous phase and an aqueous discontinuous phase containing a plurality of particles of at least one hydrogel containing a cationic polymer.
    Type: Grant
    Filed: March 19, 2020
    Date of Patent: January 2, 2024
    Assignee: ENI S.P.A.
    Inventors: Davide Moscatelli, Lucilla Del Gaudio, Paola Albonico, Alessandra Belloni, Alberto Cesana
  • Publication number: 20230392064
    Abstract: A new class of multifunctional tracers has been synthesised for use in the oil industry, specifically during waterflooding operations. They are used either in a traditional way (i.e., mapping the connections of oilfield selections) or to provide information on important physical-chemical parameters (such as oil content, temperature and rock permeability) useful for optimizing the oilfield management and subsequent improvement/increase in oil extraction. The multifunctional tracers have a polymer chain having a plurality of units different from one another and recurring along the chain and having respective specific functionalities.
    Type: Application
    Filed: October 21, 2021
    Publication date: December 7, 2023
    Applicant: ENI S.P.A.
    Inventors: Giuseppe MADDINELLI, Stefano CARMINATI, Davide MOSCATELLI, Matteo MARALDI
  • Publication number: 20230382879
    Abstract: Catalytic process for producing alkylene epoxide, selected between ethylene oxide or propylene oxide, from the corresponding alkylene carbonate, selected between ethylene carbonate or propylene carbonate, comprising the decomposition reaction of alkylene carbonate, in the presence of sodium bromide as catalyst, in which: the reaction temperature is between 207 and 245° C., and the catalyst is in amounts comprised between 5×10?4 and 8×10?3 moles per mole of alkylene carbonate. This process can be carried out continuously. A further object of the invention is the modular plant which allows carrying out such a process.
    Type: Application
    Filed: September 13, 2021
    Publication date: November 30, 2023
    Inventors: Davide MOSCATELLI, Mattia SPONCHIONI, Alberto CESANA, Gianmarco POLOTTI, Loïc RONIN
  • Publication number: 20230286624
    Abstract: There is described an inflatable life jacket (1), comprising at least a first inflatable chamber (2) and a second chamber adjacent to said first chamber (2), characterized in that said second chamber (3) comprises in its inside at least one acid resin and at least one metal having an electrical potential lower than the hydrogen standard reduction potential, said second chamber (3) being provided with unidirectional means (5) able to allow the entry of water inside it.
    Type: Application
    Filed: August 2, 2021
    Publication date: September 14, 2023
    Inventors: Davide Moscatelli, Ferruccio Resta, Roberto Primavesi
  • Publication number: 20230233442
    Abstract: A fragrance-containing microparticle of water-insoluble polymeric material, the polymer having a glass transition temperature of from 0° C. to 50° C. and a zeta potential lying within the ranges ?40 mV to ?5 mV and +5 mV to +45 mV. The microparticles have enhanced substantivity to hair, resulting in a longer-lasting fragrance.
    Type: Application
    Filed: July 23, 2021
    Publication date: July 27, 2023
    Inventors: Nelly BULGARELLI, Ian Michael HARRISON, Paula Maria Nogueira AMBROGI, Nicolò MANFREDINI, Matteo MARALDI, Massimo MORBIDELLI, Davide MOSCATELLI, Umberto Capasso PALMIERO, Mattia SPONCHIONI, Giuseppe STORTI
  • Patent number: 11624021
    Abstract: A method for controlling the permeability of an oil well includes the steps of preparing a polymerizable bicomponent system having at least a fluid with at least an olefinically unsaturated first polymerizable compound; optionally, at least one radical polymerization initiator IA, the initiator IA being activated thermally or in the presence of an accelerating compound and a fluid with a radical polymerization activator, the activator being selected from: a radical polymerization initiator IB for polymerizing the polymerizable compound, the initiator IB having an activation temperature equal to or lower than the temperature of the thief zone, an accelerator of the initiator IA, The method further includes injecting one of the fluids into the well annulus until the thief zone is reached, and injecting the remainder into the tubular element, until it comes into contact with the fluid injected through the annulus to form a blocking polymer at the thief zone.
    Type: Grant
    Filed: December 28, 2018
    Date of Patent: April 11, 2023
    Assignee: ENI S.P.A.
    Inventors: Elisa Di Biase, Matia Minelli, Davide Moscatelli, Azzurra Agostini
  • Patent number: 11603489
    Abstract: The present invention relates to a composition for inhibiting water permeation in an extraction well of a hydrocarbon oil from an underground reservoir which comprises injecting into said reservoir at least one polymerizable composition comprising: at least one hydrophilic monomer, at least one hydrophilic initiator of radical polymerization with thermal activation (hydrophilic initiator), at least one lipophilic initiator of radical polymerization with thermal activation (lipophilic initiator). The present invention also relates to the polymerizable compositions that can be used in said method.
    Type: Grant
    Filed: May 3, 2021
    Date of Patent: March 14, 2023
    Assignee: ENI S.P.A.
    Inventors: Lucilla Del Gaudio, Davide Moscatelli, Paola Albonico
  • Publication number: 20220179190
    Abstract: A digital magnifier monocle may include an eyepiece, a lens, an organic light-emitting diode screen placed between the eyepiece and the lens, and a first electronic module for the generation of a digital image. The first electronic module may be placed between the screen and the lens. The monocle may also have a second electronic module placed between the screen and the first electronic module. The second electronic module may be divided into a first unit configured for the transmission of a digital image from the first electronic module to the screen, and a second unit configured for connection with an augmented reality engine and/or the transmission of said at least one digital image from the monocle to a unit outside of the monocle. The unit external to the monocle being may be designed for the storage of the image.
    Type: Application
    Filed: March 27, 2020
    Publication date: June 9, 2022
    Applicant: EYE TECH LAB S.R.L.
    Inventors: Davide MOSCATELLI, Mauro COCCOLI, Stefano POZZI
  • Publication number: 20220169910
    Abstract: A method for inhibiting water permeation in an extraction well of a hydrocarbon fluid from an underground reservoir containing: supplying a water-in-oil emulsion an oily continuous phase and an aqueous discontinuous phase containing a plurality of particles of at least one hydrogel containing a cationic polymer; and positioning the water-in-oil emulsion in contact with the underground reservoir. The present invention also concerns a treatment fluid for hydrocarbon fluid extraction wells containing the aforementioned water-in-oil emulsion and the related preparation process.
    Type: Application
    Filed: March 19, 2020
    Publication date: June 2, 2022
    Applicant: ENI S.P.A.
    Inventors: Davide MOSCATELLI, Lucilla DEL GAUDIO, Paola ALBONICO, Alessandra BELLONI, Alberto CESANA
  • Publication number: 20210388196
    Abstract: Disclosed are methods, compositions, reagents, systems, and kits to prepare and utilize poly (?-amino ester) (PBAE) polymers, which are synthesized via Michael addition reactions of diacrylates and amines disclosed herein. Various embodiments utilize lactones and lactone derivatives to generate the diacrylate compounds. The PBAE polymers are shown to be effective biodegradable carriers for the delivery of an agent such as an organic molecule, inorganic molecule, nucleic acid, protein, peptide, polynucleotide, targeting agent, an isotopically labeled chemical compound, vaccine, or an immunological agent.
    Type: Application
    Filed: June 15, 2021
    Publication date: December 16, 2021
    Applicants: Massachusetts Institute of Technology, Politecnico di Milano
    Inventors: Umberto Capasso Palmiero, James C. Kaczmarek, Daniel Griffith Anderson, Davide Moscatelli
  • Publication number: 20210253935
    Abstract: The present invention relates to a composition for inhibiting water permeation in an extraction well of a hydrocarbon oil from an underground reservoir which comprises injecting into said reservoir at least one polymerizable composition comprising: at least one hydrophilic monomer, at least one hydrophilic initiator of radical polymerization with thermal activation (hydrophilic initiator), at least one lipophilic initiator of radical polymerization with thermal activation (lipophilic initiator). The present invention also relates to the polymerizable compositions that can be used in said method.
    Type: Application
    Filed: May 3, 2021
    Publication date: August 19, 2021
    Applicant: ENI S.P.A.
    Inventors: Lucilla DEL GAUDIO, Davide MOSCATELLI, Paola ALBONICO
  • Patent number: 11041069
    Abstract: Disclosed are methods, compositions, reagents, systems, and kits to prepare and utilize poly (?-amino ester) (PBAE) polymers, which are synthesized via Michael addition reactions of diacrylates and amines disclosed herein. Various embodiments utilize lactones and lactone derivatives to generate the diacrylate compounds. The PBAE polymers are shown to be effective biodegradable carriers for the delivery of an agent such as an organic molecule, inorganic molecule, nucleic acid, protein, peptide, polynucleotide, targeting agent, an isotopically labeled chemical compound, vaccine, or an immunological agent.
    Type: Grant
    Filed: November 2, 2018
    Date of Patent: June 22, 2021
    Assignees: Massachusetts Institute of Technology, Politecnico di Milano
    Inventors: Umberto Capasso Palmiero, James C. Kaczmarek, Daniel Griffith Anderson, Davide Moscatelli