Abstract: A method of media content discovery and playback, the method including receiving a query for media content items from a search client, the query including one or more user subscriber group identifiers and a plurality of search criteria, filtering a plurality of available media content items according to the query to generate a list of matching content items among the plurality of available media content items, returning the list of matching content items to the search client, receiving from the search client a selection token with a content item to subscriber group mapping, providing the token to a user rights manager, receiving a signature authentication from the user rights manager, and issuing a playback key to the search client.

Abstract: A closed-loop system and method for heating of target contaminant zones having environmental contaminants of concern present in the groundwater and the soil by thermal conduction, and subsequent enhancements of physical, biological and chemical processes to attenuate, remove and degrade contaminants in the target contaminant treatment zones, is disclosed. The system and method collects solar or other heat and transfers the heat via a closed-loop and a set of borehole exchangers to subsurface soil in the proximity of and/or directly to the target contaminant treatment zones. The target contaminant treatment zone may comprise contaminated soil, contaminated groundwater in an aquifer, or industrial waste comprising water and/or solids. Solar collectors or heat exchangers capturing waste heat from industrial processes may be used as the heat source.

Abstract: A closed-loop system and method for heating of target contaminant zones having environmental contaminants of concern present in the groundwater and the soil by thermal conduction, and subsequent enhancements of physical, biological and chemical processes to attenuate, remove and degrade contaminants in the target contaminant treatment zones, is disclosed. The system and method collects solar or other heat and transfers the heat via a closed-loop and a set of borehole exchangers to subsurface soil in the proximity of and/or directly to the target contaminant treatment zones. The target contaminant treatment zone may comprise contaminated soil, contaminated groundwater in an aquifer, or industrial waste comprising water and/or solids. Solar collectors or heat exchangers capturing waste heat from industrial processes may be used as the heat source.

Abstract: A closed-loop system and method for heating of target contaminant zones having environmental contaminants of concern present in the groundwater and the soil by thermal conduction, and subsequent enhancements of physical, biological and chemical processes to attenuate, remove and degrade contaminants in the target contaminant treatment zones, is disclosed. The system and method collects solar or other heat and transfers the heat via a closed-loop and a set of borehole exchangers to subsurface soil in the proximity of and/or directly to the target contaminant treatment zones. The target contaminant treatment zone may comprise contaminated soil, contaminated groundwater in an aquifer, or industrial waste comprising water and/or solids. Solar collectors or heat exchangers capturing waste heat from industrial processes may be used as the heat source.

Abstract: A closed-loop system and method for heating of target contaminant zones having environmental contaminants of concern present in the groundwater and the soil by thermal conduction, and subsequent enhancements of physical, biological and chemical processes to attenuate, remove and degrade contaminants in the target contaminant treatment zones, is disclosed. The system and method collects solar or other heat and transfers the heat via a closed-loop and a set of borehole exchangers to subsurface soil in the proximity of and/or directly to the target contaminant treatment zones. The target contaminant treatment zone may comprise contaminated soil, contaminated groundwater in an aquifer, or industrial waste comprising water and/or solids. Solar collectors or heat exchangers capturing waste heat from industrial processes may be used as the heat source.

Abstract: A closed-loop system and method for heating of target contaminant treatment zones (150) having environmental contaminants of concern present in the groundwater and the soil by thermal conduction, and subsequent enhancement of physical, biological and chemical processes to attenuate, remove and degrade contaminants in the target contaminant treatment zones, is disclosed. The system and method collects solar or other heat and transfers that heat via a closed-loop and a set of borehole exchangers (120) to subsurface soil in the proximity of and/or directly to the target contaminant treatment zones. The target contaminant treatment zone may comprise contaminated soil, contaminated groundwater in an aquifer, or industrial waste comprising water and/or solids. Solar collectors or heat exchangers capturing waste heat from industrial processes may be used as the heat source (110).

Abstract: A method of media content discovery and playback, the method including receiving a query for media content items from a search client, the query including one or more user subscriber group identifiers and a plurality of search criteria, filtering a plurality of available media content items according to the query to generate a list of matching content items among the plurality of available media content items, returning the list of matching content items to the search client, receiving from the search client a selection token with a content item to subscriber group mapping, providing the token to a user rights manager, receiving a signature authentication from the user rights manager, and issuing a playback key to the search client.

Abstract: A closed-loop system and method for heating of target contaminant treatment zones (150) having environmental contaminants of concern present in the groundwater and the soil by thermal conduction, and subsequent enhancement of physical, biological and chemical processes to attenuate, remove and degrade contaminants in the target contaminant treatment zones, is disclosed. The system and method collects solar or other heat and transfers that heat via a closed-loop and a set of borehole exchangers (120) to subsurface soil in the proximity of and/or directly to the target contaminant treatment zones. The target contaminant treatment zone may comprise contaminated soil, contaminated groundwater in an aquifer, or industrial waste comprising water and/or solids. Solar collectors or heat exchangers capturing waste heat from industrial processes may be used as the heat source (110).

Abstract: The present application provides novel binding proteins, including human binding proteins that specifically bind to the human ErbB2.

Abstract: The present invention provides monoclonal antibodies for human TrkB. In certain embodiments the inventive antibodies bind and activate human TrkB. In certain embodiments the inventive antibodies are selective for human TrkB in that they do not bind (or activate) human TrkA or human TrkC. In some embodiments the inventive monoclonal antibodies cross-react with murine TrkB. Humanized or veneered versions of the inventive antibodies are also encompassed. Pharmaceutical compositions that comprise inventive antibodies are provided as are methods for preparing the inventive antibodies and methods of using these for treatment, detection or purification purposes.

Abstract: The present invention provides monoclonal antibodies for human TrkB. In certain embodiments the inventive antibodies bind and activate human TrkB. In certain embodiments the inventive antibodies are selective for human TrkB in that they do not bind (or activate) human TrkA or human TrkC. In some embodiments the inventive monoclonal antibodies cross-react with murine TrkB. Humanized or veneered versions of the inventive antibodies are also encompassed. Pharmaceutical compositions that comprise inventive antibodies are provided as are methods for preparing the inventive antibodies and methods of using these for treatment, detection or purification purposes.

Abstract: The present application provides novel binding proteins, including human binding proteins that specifically bind to the human ErbB2.

Abstract: The invention provides isolated nucleic acid molecules and polypeptide molecules that encode glycoprotein VI, a platelet membrane glycoprotein that is involved platelet-collagen interactions. The invention also provides antisense nucleic acid molecules, expression vectors containing the nucleic acid molecules of the invention, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which a nucleic acid molecule of the invention has been introduced or disrupted. The invention still further provides isolated polypeptides, fusion polypeptides, antigenic peptides and antibodies. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.

Abstract: The invention provides isolated nucleic acid molecules and polypeptide molecules that encode glycoprotein VI, a platelet membrane glycoprotein that is involved platelet-collagen interactions. The invention also provides antisense nucleic acid molecules, expression vectors containing the nucleic acid molecules of the invention, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which a nucleic acid molecule of the invention has been introduced or disrupted. The invention still further provides isolated polypeptides, fusion polypeptides, antigenic peptides and antibodies. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.

Abstract: The present invention provides a grommet cover assembly for selectively substantially blocking view of at least one opening in a planar member surface. The assembly comprises a mounting coupler mounted to the planar member surface proximate the first opening and a cover. The cover includes a flat cover member and a cover coupler, wherein the cover member includes at least one supporting leg. The cover coupler links to the mounting coupler to provide a hinged axis the cover member is rotated around. Thus, when the cover member is adjacent the opening, at least a portion of the opening is blocked from view. Methods of use and assembly are also provided.

Abstract: A glass run channel assembly for mounting on the door frame of an automotive vehicle and for accommodating a glass run seal and a glass window comprising a glass run channel upper frame, a glass run guide, and a glass run lower frame frame, each having a bottom wall and two side walls disposed on either side of the bottom wall, forming a U-shape. In operation, the lower frame is slidably engaged within the guide until the lower frame converges with a lower frame stop formed by a side wall of the guide. A tab locator is formed in each of the two side walls of the upper frame to guide the guide as it slidably engages within the upper frame. Upon sliding within the upper frame, a channel upper stop formed in a side wall of the guide converges with one of the tab locators on the upper frame locator, thereby preventing the guide from sliding too far into the upper frame.

Abstract: The invention provides isolated nucleic acid molecules and polypeptide molecules that encode glycoprotein VI, a platelet membrane glycoprotein that is involved platelet-collagen interactions. The invention also provides antisense nucleic acid molecules, expression vectors containing the nucleic acid molecules of the invention, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which a nucleic acid molecule of the invention has been introduced or disrupted. The invention still further provides isolated polypeptides, fusion polypeptides, antigenic peptides and antibodies. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.

Abstract: The invention provides isolated nucleic acid molecules and polypeptide molecules that encode glycoprotein V1, a platelet membrane glycoprotein that is involved platelet-collagen interactions. The invention also provides antisense nucleic acid molecules, expression vectors containing the nucleic acid molecules of the invention, host cells into which the exposure vectors have been introduced, and non-human transgenic animals in which a nucleic acid molecule of the invention has been introduced or disrupted. The invention still further provides isolated polypeptides, fusion polypeptides, antigenic peptides and antibodies. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.

Abstract: The invention provides isolated nucleic acid molecules and polypeptide molecules that encode glycoprotein VI, a platelet membrane glycoprotein that is involved platelet-collagen interactions. The invention also provides antisense nucleic acid molecules, expression vectors containing the nucleic acid molecules of the invention, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which a nucleic acid molecule of the invention has been introduced or disrupted. The invention still further provides isolated polypeptides, fusion polypeptides, antigenic peptides and antibodies. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.

Abstract: A glass run channel assembly for mounting on the door frame of an automotive vehicle and for accommodating a glass run seal and a glass window comprising a glass run channel upper frame, a glass run guide, and a glass run lower frame frame, each having a bottom wall and two side walls disposed on either side of the bottom wall, forming a U-shape. In operation, the lower frame is slidably engaged within the guide until the lower frame converges with a lower frame stop formed by a side wall of the guide. A tab locator is formed in each of the two side walls of the upper frame to guide the guide as it slidably engages within the upper frame. Upon sliding within the upper frame, a channel upper stop formed in a side wall of the guide converges with one of the tab locators on the upper frame locator, thereby preventing the guide from sliding too far into the upper frame.