Patents by Inventor Daw-Iong Albert Kwok

Daw-Iong Albert Kwok has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthesis of amine substituted 4,5,6,7-tetrahydrobenzothiazole compounds
    Patent number: 10208003
    Abstract: The present invention is related to an improved process for the preparation of amino-substituted 4,5,6,7-tetrahydrobenzothiazole compounds of formula I, such as the compound 2-amino-4,5,6,7-tetrahydro-6-(n-propylamino)benzothiazole. The invention further relates to an improved synthesis of (R)-2-amino-4,5,6,7-tetrahydro-6-(n-propylamino)benzothiazole. The invention also relates to the methods and intermediates associated with the synthetic process.
    Type: Grant
    Filed: October 24, 2016
    Date of Patent: February 19, 2019
    Assignee: Knopp Biosciences LLC
    Inventors: Weirong Chen, Michael Humora, Daw-Iong Albert Kwok, William F. Kiesman, Erwin Ayandra Irdam
  • SYNTHESIS OF AMINE SUBSTITUTED 4,5,6,7-TETRAHYDROBENZOTHIAZOLE COMPOUNDS
    Publication number: 20170158648
    Abstract: The present invention is related to an improved process for the preparation of amino-substituted 4,5,6,7-tetrahydrobenzothiazole compounds of formula I, such as the compound 2-amino-4,5,6,7-tetrahydro-6-(n-propylamino)benzothiazole. The invention further relates to an improved synthesis of (R)-2-amino-4,5,6,7-tetrahydro-6-(n-propylamino)benzothiazole. The invention also relates to the methods and intermediates associated with the synthetic process.
    Type: Application
    Filed: October 24, 2016
    Publication date: June 8, 2017
    Inventors: Weirong CHEN, Michael HUMORA, Daw-Iong Albert KWOK, William F. KIESMAN, Erwin Ayandra IRDAM
  • SYNTHESIS OF AMINE SUBSTITUTED 4,5,6,7-TETRAHYDROBENZOTHIAZOLE COMPOUNDS
    Publication number: 20150126745
    Abstract: The present invention is related to an improved process for the preparation of amino-substituted 4,5,6,7-tetrahydrobenzothiazole compounds of formula I, such as the compound 2-amino-4,5,6,7-tetrahydro-6-(n-propylamino)benzothiazole. The invention further relates to an improved synthesis of (R)-2-amino-4,5,6,7-tetrahydro-6-(n-propylamino)benzothiazole. The invention also relates to the methods and intermediates associated with the synthetic process.
    Type: Application
    Filed: December 21, 2012
    Publication date: May 7, 2015
    Inventors: Weirong Chen, Michael Humora, Daw-Iong Albert Kwok, William F. Kiesman, Erwin Ayandra Irdam
  • Process for the preparation of 17-esters of 9 .alpha., 21-dihalo-pregnane-11 .beta., 17 .alpha.-diol-20-ones
    Patent number: 5886200
    Abstract: The invention provides an improved process for the preparation of 17-esters of 9.alpha.,21 -dihalo-pregnane-11.beta.,17.alpha.-diol-20-ones, and in particular for the preparation of 17-esters of anti-inflammatory steroids according to the following scheme: ##STR1## wherein RCO, R.sup.1, X, Y and the dotted line are as defined in the specification. The novel process is especially suitable for the preparation of Mometasone Furoate.
    Type: Grant
    Filed: June 25, 1997
    Date of Patent: March 23, 1999
    Assignee: Schering Corporation
    Inventors: Daw-Iong Albert Kwok, David J. S. Tsai, Chou-Hong Tann, Xiaoyong Fu