Patents by Inventor Daw-long Albert Kwok

Daw-long Albert Kwok has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DIROXIMEL FUMARATE PARTICLES HAVING IMPROVED FLOW PROPERTIES AND METHODS OF MAKING SAME
    Publication number: 20240400506
    Abstract: Many active pharmaceutical ingredients (API) are available in tablet form. Particles of the API should have a favorable compaction profile in order to be compressed into tablets, especially when the API is present in a large weight percentage in the tablet. Disclosed herein are particles of diroximel fumarate having improved characteristic for tablet formation, and methods of producing the same.
    Type: Application
    Filed: September 16, 2022
    Publication date: December 5, 2024
    Inventors: Liang Chen, Erwin Irdam, Daw-long Albert Kwok, Nocole Madden, John Mascho
  • SYNTHETIC PREPARATION FOR DIROXIMEL FUMARATE
    Publication number: 20240308958
    Abstract: Disclosed is a method of preparing diroximel fumarate represented by the following structural formula (I) The method comprises reacting ethy lene carbonate with succinimide to form a hydroxyethyl succinimide intermediate; and reacting the intermediate with monomethyl fumarate to form the product compound.
    Type: Application
    Filed: June 14, 2022
    Publication date: September 19, 2024
    Inventors: Daw-long Albert KWOK, Chao Fei, Erwin Irdam, Donald Walker, Markus Grohmann, Jens Mohr, Janina Bucher
  • Synthesis of amine substituted 4,5,6,7-tetrahydrobenzothiazole compounds
    Patent number: 9512096
    Abstract: The present invention is related to an improved process for the preparation of amino-substituted 4,5,6,7-tetrahydrobenzothiazole compounds of formula I, such as the compound 2-amino-4,5,6,7-tetrahydro-6-(n-propylamino)benzothiazole. The invention further relates to an improved synthesis of (R)-2-amino-4,5,6,7-tetrahydro-6-(n-propylamino)benzothiazole. The invention also relates to the methods and intermediates associated with the synthetic process.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: December 6, 2016
    Assignee: Knopp Biosciences, LLP
    Inventors: Weirong Chen, Michael Humora, Daw-long Albert Kwok, William F. Kiesman, Erwin Ayandra Irdam