Patents by Inventor DaWei Cui

DaWei Cui has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Therapeutically active compounds and their methods of use
    Patent number: 11021515
    Abstract: Provided are methods of treating a cancer characterized by the presence of a mutant allele of IDH1/2 comprising administering to a subject in need thereof a compound described here.
    Type: Grant
    Filed: May 11, 2020
    Date of Patent: June 1, 2021
    Assignee: Agios Pharmaceuticals, Inc.
    Inventors: Rene M. Lemieux, Janeta Popovici-Muller, Jeremy Travins, Zhenwei Cai, Dawei Cui, Ding Zhou
  • PYRUVATE KINASE ACTIVATORS FOR USE IN TREATING BLOOD DISORDERS
    Publication number: 20210130371
    Abstract: Described herein are compounds that activate pyruvate kinase R, pharmaceutical compositions and methods of use thereof. These compounds are represented by Formula (I): wherein R1, R2, L1, and L2 are as defined herein.
    Type: Application
    Filed: August 15, 2018
    Publication date: May 6, 2021
    Inventors: Giovanni Cianchetta, Tao Liu, Anil Kumar Padyana, Zhihua Sui, Zhenwei Cai, Dawei Cui, Jingjing Ji
  • PYRUVATE KINASE ACTIVATORS FOR USE IN TREATING BLOOD DISORDERS
    Publication number: 20210077490
    Abstract: Described herein are compounds that activate pyruvate kinase, pharmaceutical compositions and methods of use thereof. These compounds are represented by Formula (I) wherein R1, R2, Ra, Rb, Rj, Rk, and Q are as defined herein.
    Type: Application
    Filed: November 19, 2020
    Publication date: March 18, 2021
    Inventors: Giovanni Cianchetta, Tao Liu, Anil Kumar Padyana, Zhihua Sui, Zhenwei Cai, Dawei Cui, Jingjing Ji
  • THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE
    Publication number: 20210024575
    Abstract: Provided are methods of treating a cancer characterized by the presence of a mutant allele of IDH1/2 comprising administering to a subject in need thereof a compound described here.
    Type: Application
    Filed: June 5, 2020
    Publication date: January 28, 2021
    Inventors: Janeta Popovici-Muller, Rene M. Lemieux, Jeremy Travins, Zhenwei Cai, Dawei Cui, Ding Zhou
  • THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE
    Publication number: 20200339626
    Abstract: Provided are methods of treating a cancer characterized by the presence of a mutant allele of IDH1/2 comprising administering to a subject in need thereof a compound described here.
    Type: Application
    Filed: May 11, 2020
    Publication date: October 29, 2020
    Inventors: Rene M. Lemieux, Janeta Popovici-Muller, Jeremy Travins, Zhenwei Cai, Dawei Cui, Ding Zhou
  • Therapeutically active compounds and their methods of use
    Patent number: 10717764
    Abstract: Provided are methods of treating a cancer characterized by the presence of a mutant allele of IDH1/2 comprising administering to a subject in need thereof a compound described here.
    Type: Grant
    Filed: May 31, 2019
    Date of Patent: July 21, 2020
    Assignee: Agios Pharmaceuticals, Inc.
    Inventors: Janeta Popovici-Muller, Rene M. Lemieux, Jeremy Travins, Zhenwei Cai, Dawei Cui, Ding Zhou
  • PYRUVATE KINASE ACTIVATORS FOR USE IN TREATING BLOOD DISORDERS
    Publication number: 20200207785
    Abstract: Described herein are compounds that activate pyruvate kinase, pharmaceutical compositions and methods of use thereof.
    Type: Application
    Filed: August 15, 2018
    Publication date: July 2, 2020
    Inventors: Giovanni Cianchetta, Tao Liu, Anil Kumar Padyana, Zhihua Sui, Zhenwei Cai, Dawei Cui, Jingjing Ji
  • PYRUVATE KINASE MODULATORS AND USE THEREOF
    Publication number: 20200206225
    Abstract: Described herein are methods of using compounds of Formula (I) to modulate PKM2 activity in a subject. These compounds are represented by Formula (I): wherein R1, R2, L1, and L2 are as defined herein.
    Type: Application
    Filed: August 15, 2018
    Publication date: July 2, 2020
    Applicant: Agios Pharmaceuticals, Inc.
    Inventors: Giovanni Cianchetta, Charles Kung, Tao Liu, Anil Kumar Padyana, Zhihua Sui, Zhenwei Cai, Dawei Cui, Jingjing Ji
  • Therapeutically active compounds and their methods of use
    Patent number: 10689414
    Abstract: Provided are methods of treating a cancer characterized by the presence of a mutant allele of IDH1/2 comprising administering to a subject in need thereof a compound described here.
    Type: Grant
    Filed: March 8, 2018
    Date of Patent: June 23, 2020
    Assignee: Agios Pharmaceuticals, Inc.
    Inventors: Rene M. Lemieux, Janeta Popovici-Muller, Jeremy Travins, Zhenwei Cai, Dawei Cui, Ding Zhou
  • Therapeutically active compositions and their methods of use
    Patent number: 10640534
    Abstract: Provided are methods of treating a cancer characterized by the presence of a mutant allele of IDH1/2 comprising administering to a subject in need thereof a compound described here.
    Type: Grant
    Filed: November 10, 2017
    Date of Patent: May 5, 2020
    Assignee: Agios Pharmaceuticals, Inc.
    Inventors: Janeta Popovici-Muller, Rene M. Lemieux, Jeremy Travins, Zhenwei Cai, Dawei Cui, Ding Zhou
  • THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE
    Publication number: 20190315802
    Abstract: Provided are methods of treating a cancer characterized by the presence of a mutant allele of IDH1/2 comprising administering to a subject in need thereof a compound described here.
    Type: Application
    Filed: May 31, 2019
    Publication date: October 17, 2019
    Inventors: Janeta Popovici-Muller, Rene M. Lemieux, Jeremy Travins, Zhenwei Cai, Dawei Cui, Ding Zhou
  • Fuming furnace with lead collecting and discharging function
    Patent number: 10443112
    Abstract: Disclosed is a fuming furnace with a lead collecting and discharging function, the fuming furnace comprising a furnace body; the furnace body is provided with a hearth therein and a tuyere thereon; the bottom of the hearth forms a molten pool; the furnace body is further provided with a slag discharging outlet and a lead discharging outlet thereon; the furnace body comprises a furnace bottom water jacket and a hearth water jacket; the furnace bottom water jacket is provided with a refractory brick layer at the inner wall thereof; the refractory brick layer is provided with a lead collecting and discharging channel therein for collecting and discharging lead; the lead collecting and discharging channel is in communication with the lead discharging outlet, and the lead collecting and discharging channel is in communication with the molten pool via joints between the refractory bricks forming the refractory brick layer.
    Type: Grant
    Filed: September 15, 2015
    Date of Patent: October 15, 2019
    Assignee: CHINA ENFI ENGINEERING CORPORATION
    Inventors: Dawei Cui, Kefei Cao, Chuangu Wu, Shuangjie Feng, Xin Xu, Zhenmin Zhang
  • Refractory protection layer for metallurgical furnace
    Patent number: 10415883
    Abstract: The present disclosure discloses a refractory protection layer for a metallurgical furnace, which includes a insulating layer, a permanent layer built with a refractory brick and arranged on the insulating layer, a working layer built with a refractory brick and arranged on the permanent layer, and a first anti-permeation layer made of ramming mass and arranged on the working layer. The refractory protection layer for the metallurgical furnace described in the present disclosure embodiments has both high temperature resistance and good permeability resistance.
    Type: Grant
    Filed: December 20, 2016
    Date of Patent: September 17, 2019
    Assignee: CHINA ENFI ENGINEERING CORPORATION
    Inventors: Budong Zheng, Zhenmin Zhang, Liyu Lu, Kefei Cao, Dawei Cui, Chuangu Wu, Haikuo Sun
  • THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE
    Publication number: 20190023737
    Abstract: Provided are methods of treating a cancer characterized by the presence of a mutant allele of IDH1/2 comprising administering to a subject in need thereof a compound described here.
    Type: Application
    Filed: March 8, 2018
    Publication date: January 24, 2019
    Inventors: Rene M. Lemieux, Janeta Popovici-Muller, Jeremy Travins, Zhenwei Cai, Dawei Cui, Ding Zhou
  • THERAPEUTICALLY ACTIVE COMPOSITIONS AND THEIR METHODS OF USE
    Publication number: 20180194802
    Abstract: Provided are methods of treating a cancer characterized by the presence of a mutant allele of IDH1/2 comprising administering to a subject in need thereof a compound described here.
    Type: Application
    Filed: November 10, 2017
    Publication date: July 12, 2018
    Inventors: Janeta Popovici-Muller, Rene M. Lemieux, Jeremy Travins, Zhenwei Cai, Dawei Cui, Ding Zhou
  • REFRACTORY PROTECTION LAYER FOR METALLURGICAL FURNACE
    Publication number: 20180172350
    Abstract: The present disclosure discloses a refractory protection layer for a metallurgical furnace, which includes a insulating layer, a permanent layer built with a refractory brick and arranged on the insulating layer, a working layer built with a refractory brick and arranged on the permanent layer, and a first anti-permeation layer made of ramming mass and arranged on the working layer. The refractory protection layer for the metallurgical furnace described in the present disclosure embodiments has both high temperature resistance and good permeability resistance.
    Type: Application
    Filed: December 20, 2016
    Publication date: June 21, 2018
    Inventors: Budong ZHENG, Zhenmin ZHANG, Liyu LU, Kefei CAO, Dawei CUI, Chuangu WU, Haikuo SUN
  • Therapeutically active compositions and their methods of use
    Patent number: 9850277
    Abstract: Provided are methods of treating a cancer characterized by the presence of a mutant allele of IDH1/2 comprising administering to a subject in need thereof a compound described here.
    Type: Grant
    Filed: September 28, 2016
    Date of Patent: December 26, 2017
    Assignee: AGIOS PHARMACEUTICALS, INC.
    Inventors: Janeta Popovici-Muller, Rene M. Lemieux, Jeremy Travins, Zhenwei Cai, Dawei Cui, Ding Zhou
  • FUMING FURNACE WITH LEAD COLLECTING AND DISCHARGING FUNCTION
    Publication number: 20170283907
    Abstract: Disclosed is a fuming furnace with a lead collecting and discharging function, the fuming furnace comprising a furnace body; the furnace body is provided with a hearth therein and a tuyere thereon; the bottom of the hearth forms a molten pool; the furnace body is further provided with a slag discharging outlet and a lead discharging outlet thereon; the furnace body comprises a furnace bottom water jacket and a hearth water jacket; the furnace bottom water jacket is provided with a refractory brick layer at the inner wall thereof; the refractory brick layer is provided with a lead collecting and discharging channel therein for collecting and discharging lead; the lead collecting and discharging channel is in communication with the lead discharging outlet, and the lead collecting and discharging channel is in communication with the molten pool via joints between the refractory bricks forming the refractory brick layer.
    Type: Application
    Filed: September 15, 2015
    Publication date: October 5, 2017
    Inventors: Dawei CUI, Kefei CAO, Chuangu WU, Shuangjie FENG, Xin XU, Zhenmin ZHANG
  • THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE
    Publication number: 20170057994
    Abstract: Provided are methods of treating a cancer characterized by the presence of a mutant allele of IDH1/2 comprising administering to a subject in need thereof a compound described here.
    Type: Application
    Filed: November 9, 2016
    Publication date: March 2, 2017
    Inventors: Rene M. Lemieux, Janeta Popovici-Muller, Jeremy M. Travins, Zhenwei Cai, Dawei Cui, Ding Zhou
  • THERAPEUTICALLY ACTIVE COMPOSITIONS AND THEIR METHODS OF USE
    Publication number: 20170015703
    Abstract: Provided are methods of treating a cancer characterized by the presence of a mutant allele of IDH1/2 comprising administering to a subject in need thereof a compound described here.
    Type: Application
    Filed: September 28, 2016
    Publication date: January 19, 2017
    Inventors: Janeta Popovici-Muller, Rene M. Lemieux, Jeremy Travins, Zhenwei Cai, Dawei Cui, Ding Zhou