Patents by Inventor Dawei Sheng

Dawei Sheng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CONJUGATES OF A FACTOR VIII MOIETY HAVING AN OXIME-CONTAINING LINKAGE
    Publication number: 20230241181
    Abstract: The present disclosure provides conjugates comprising a Factor VIII moiety covalently attached via an oxime-containing linkage to a water-soluble polymer, such as for example, a polyethylene glycol polymer. Methods for preparing and for administering such conjugates, are also provided, as are water-soluble polymer oxyamine reagents useful for preparing the subject conjugates, among other things.
    Type: Application
    Filed: February 27, 2023
    Publication date: August 3, 2023
    Inventors: Mary J. Bossard, Dawei Sheng
  • Conjugates of a factor VIII moiety having an oxime-containing linkage
    Patent number: 11628205
    Abstract: The present disclosure provides conjugates comprising a Factor VIII moiety covalently attached via an oxime-containing linkage to a water-soluble polymer, such as for example, a polyethylene glycol polymer. Methods for preparing and for administering such conjugates, are also provided, as are water-soluble polymer oxyamine reagents useful for preparing the subject conjugates, among other things.
    Type: Grant
    Filed: July 21, 2017
    Date of Patent: April 18, 2023
    Assignee: Nektar Therapeutics
    Inventors: Mary J. Bossard, Dawei Sheng
  • CONJUGATES OF A FACTOR VIII MOIETY HAVING AN OXIME-CONTAINING LINKAGE
    Publication number: 20210369817
    Abstract: The present disclosure provides conjugates comprising a Factor VIII moiety covalently attached via an oxime-containing linkage to a water-soluble polymer, such as for example, a polyethylene glycol polymer. Methods for preparing and for administering such conjugates, are also provided, as are water-soluble polymer oxyamine reagents useful for preparing the subject conjugates, among other things.
    Type: Application
    Filed: July 21, 2017
    Publication date: December 2, 2021
    Inventors: Mary J. Bossard, Dawei Sheng
  • POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES
    Publication number: 20190070251
    Abstract: The invention provides peptides that are chemically modified by covalent attachment of a water-soluble oligomer. A conjugate of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from the characteristics of the peptide not attached to the water-soluble oligomer.
    Type: Application
    Filed: April 28, 2017
    Publication date: March 7, 2019
    Inventors: Mary J. Bossard, Steven O. Roczniak, Harold Zappe, Yujun Wang, Ping Zhang, Dawei Sheng, C. Simone Jude-Fishburn, Elizabeth Louise Minamitani, Xiaofeng Liu, Haim Moskowitz, Dennis G. Fry, Cherie F. Ali, Christine Taylor Brew
  • Polymer conjugates of therapeutic peptides
    Patent number: 9682153
    Abstract: The invention provides peptides that are chemically modified by covalent attachment of a water-soluble oligomer. A conjugate of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from the characteristics of the peptide not attached to the water-soluble oligomer.
    Type: Grant
    Filed: March 20, 2015
    Date of Patent: June 20, 2017
    Assignee: Nektar Therapeutics
    Inventors: Mary J. Bossard, Steven O. Roczniak, Harold Zappe, Yujun Wang, Ping Zhang, Dawei Sheng, C. Simone Jude-Fishburn, Elizabeth Louise Minamitani, Xiaofeng Liu, Haim Moskowitz, Dennis G. Fry, Cherie F. Ali, Christine Taylor Brew
  • Conjugates of small-interfering nucleic acids
    Patent number: 9433684
    Abstract: The present invention relates to conjugates of small-interfering nucleic acids (siNA). Compositions of siNA suited for administration to a patient are described. Methods for delivering the compositions are also described.
    Type: Grant
    Filed: August 19, 2009
    Date of Patent: September 6, 2016
    Assignee: Nektar Therapeutics
    Inventors: Samuel P. McManus, Timothy A. Riley, Sean M. Culbertson, Antoni Kozlowski, Dennis G. Fry, Xuejun Yuan, Dawei Sheng, Vidula R. Dixit
  • POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES
    Publication number: 20160022828
    Abstract: The invention provides peptides that are chemically modified by covalent attachment of a water-soluble oligomer. A conjugate of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from the characteristics of the peptide not attached to the water-soluble oligomer.
    Type: Application
    Filed: March 20, 2015
    Publication date: January 28, 2016
    Inventors: Mary J. Bossard, Steven O. Roczniak, Harold Zappe, Yujun Wang, Ping Zhang, Dawei Sheng, C. Simone Jude-Fishburn, Elizabeth Louise Minamitani, Xiaofeng Liu, Haim Moskowitz, Dennis G. Fry, Cherie F. Ali, Christine Taylor Brew
  • Methods and compositions for detecting one or more target agents using tracking components
    Publication number: 20120269728
    Abstract: The present invention provides devices and methods for real time detection of target agents in a sample. These devices utilize tracking technology and selective binding to allow the identification of one or more target agents in a sample, and preferably in a biological sample. The present invention provides specific embodiments employing radio frequency identification devices.
    Type: Application
    Filed: June 21, 2007
    Publication date: October 25, 2012
    Applicant: Antara BioSciences Inc.
    Inventors: I-Min M. Jen, Mark O. Trulson, Kilian Dill, Marc R. Labgold, Dawei Sheng, George G. Jokhadze, Chandramohan V. Ammini, Peter Lobban
  • CONJUGATES PF SMALL-INTERFERING NUCLEIC ACIDS
    Publication number: 20120100096
    Abstract: The present invention relates to conjugates of small-interfering nucleic acids (siNA). Compositions of siNA suited for administration to a patient are described. Methods for delivering the compositions are also described.
    Type: Application
    Filed: August 19, 2008
    Publication date: April 26, 2012
    Applicant: Nektar Therapeutics
    Inventors: Samuel P. McManus, Timothy A. Riley, Sean M. Culbertson, Antoni Kozlowski, Dennis G. Fry, Xuejun Yuan, Dawei Sheng, Vidula R. Dixit
  • POLYMER CONJUGATES OF ZICONOTIDE PEPTIDES
    Publication number: 20110171163
    Abstract: The invention provides peptides that are chemically modified by covalent attachment of a water soluble oligomer. A conjugate of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from the characteristics of the peptide not attached to the water soluble oligomer.
    Type: Application
    Filed: September 17, 2009
    Publication date: July 14, 2011
    Applicant: Nektar Therapeutics
    Inventors: Dawei Sheng, Harold Zappe, C. Simone Jude-Fishburn, Steven O. Roczniak, Mary J. Bossard
  • POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES
    Publication number: 20110166063
    Abstract: The invention provides peptides that are chemically modified by covalent attachment of a water-soluble oligomer. A conjugate of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from the characteristics of the peptide not attached to the water-soluble oligomer.
    Type: Application
    Filed: September 17, 2009
    Publication date: July 7, 2011
    Applicant: Nektar Therapeutics
    Inventors: Mary J. Bossard, Steven O. Roczniak, Harold Zappe, Yujun Wang, Ping Zhang, Dawei Sheng, C. Simone Jude-Fishburn, Elizabeth Louise Minamitani, Xiaofeng Liu, Haim Moskowitz, Dennis G. Fry, Cherie F. Ali, Christine Taylor Brew
  • Fluorescent energy transfer labeled nucleic acid substrates and methods of use thereof
    Publication number: 20050250134
    Abstract: Methods and compositions for detecting a target nucleic acid in a sample are provided. Also provided are methods and compositions for detecting a plurality of target nucleic acids in a sample. Sets of components for use in a subject method are provided; as well as compositions that include a subject set.
    Type: Application
    Filed: March 1, 2005
    Publication date: November 10, 2005
    Inventors: Dawei Sheng, Marcia Tan, Robert Larsen