Patents by Inventor Dawn Chandler

Dawn Chandler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CANCER-TARGETED, VIRUS-ENCODED, REGULATABLE T (CATVERT) OR NK CELL (CATVERN) LINKERS
    Publication number: 20220257760
    Abstract: Recombinant polynucleotides and vectors containing an engineered (artificial) exon-intron-exon gene structure in a transgene are provided, which undergoes splicing when it is expressed in a target cell.
    Type: Application
    Filed: February 19, 2020
    Publication date: August 18, 2022
    Applicant: RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL
    Inventors: Timothy P. Cripe, Chun-yu Chen, Brian Hutzen, Mark Currier, Pin-yi Wang, Dawn Chandler
  • Tumor suppressor CAR-1
    Patent number: 7169384
    Abstract: The present invention relates to a new tumor suppressor, designated CAR-1, the gene for which is located on the short arm of human chromosome 1. This gene is directly implicated in colon, kidney and breast cancers, and the CAR-1 ubiquitous expression of the corresponding transcript suggests that it may be involved in yet others. Thus, one aspect of the invention is the diagnosis of CAR-1-related malignancies. The full length cDNA for CAR-1, as well as oligonucleotides derived therefrom, are disclosed. Screening methods for modulators of CAR-1 function and expression, as well as methods for cancer therapy, are described.
    Type: Grant
    Filed: June 15, 2005
    Date of Patent: January 30, 2007
    Assignee: Board of Regents, The University of Texas System
    Inventors: Ann Killary, Steve Lott, Dawn Chandler
  • Tumor suppressor CAR-1
    Publication number: 20060019281
    Abstract: The present invention relates to a new tumor suppressor, designated CAR-1, the gene for which is located on the short arm of human chromosome 1. This gene is directly implicated in colon, kidney and breast cancers, and the CAR-1 ubiquitous expression of the corresponding transcript suggests that it may be involved in yet others. Thus, one aspect of the invention is the diagnosis of CAR-1-related malignancies. The full length cDNA for CAR-1, as well as oligonucleotides derived therefrom, are disclosed. Screening methods for modulators of CAR-1 function and expression, as well as methods for cancer therapy, are described.
    Type: Application
    Filed: June 15, 2005
    Publication date: January 26, 2006
    Inventors: Ann Killary, Steve Lott, Dawn Chandler
  • Tumor suppressor CAR-1
    Patent number: 6943245
    Abstract: The present invention relates to a new tumor suppressor, designated CAR-1, the gene for which is located on the short arm of human chromosome 1. This gene is directly implicated in colon, kidney and breast cancers, and the CAR-1 ubiquitous expression of the corresponding transcript suggests that it may be involved in yet others. Thus, one aspect of the invention is the diagnosis of CAR-1-related malignancies. The full length cDNA for CAR-1, as well as oligonucleotides derived therefrom, are disclosed. Screening methods for modulators of CAR-1 function and expression, as well as methods for cancer therapy, are described.
    Type: Grant
    Filed: August 9, 2001
    Date of Patent: September 13, 2005
    Assignee: Board of Regents, The University of Texas System
    Inventors: Ann Killary, Steve Lott, Dawn Chandler
  • Tumor suppressor CAR-1
    Publication number: 20020119541
    Abstract: The present invention relates to a new tumor suppressor, designated CAR-1, the gene for which is located on the short arm of human chromosome 1. This gene is directly implicated in colon, kidney and breast cancers, and the CAR-1 ubiquitous expression of the corresponding transcript suggests that it may be involved in yet others. Thus, one aspect of the invention is the diagnosis of CAR-1-related malignancies. The full length cDNA for CAR-1, as well as oligonucleotides derived therefrom, are disclosed. Screening methods for modulators of CAR-1 function and expression, as well as methods for cancer therapy, are described.
    Type: Application
    Filed: August 9, 2001
    Publication date: August 29, 2002
    Inventors: Ann Killary, Steve Lott, Dawn Chandler