Patents by Inventor Dawn Gross

Dawn Gross has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Borrelia burgdorferi polypeptides and uses thereof
    Patent number: 6689364
    Abstract: The present invention provides novel polypeptides which are substantially free of a B. burgdorferi spirochete or fragments thereof and which are thus useful in compositions and methods for the treatment and prevention of B. burgdorferi infection and Lyme disease. In one preferred embodiment, this invention provides modified OspA polypeptides and pharmaceutically effective compositions and methods comprising those polypeptides. Preferred modified OspA polypeptides are characterized by modifications which diminish and/or ablate their ability to bind the human MHC allele HLA-DRB1*0401.
    Type: Grant
    Filed: March 20, 2001
    Date of Patent: February 10, 2004
    Assignee: Tufts University
    Inventors: Brigitte T. Huber, Theresa Willett, Abbie Meyer, Dawn Gross
  • Novel borrelia burgdorferi polypeptides and uses thereof
    Publication number: 20020039586
    Abstract: The present invention provides novel polypeptides which are substantially free of a B. burgdorferi spirochete or fragments thereof and which are thus useful in compositions and methods for the treatment and prevention of B. burgdorferi infection and Lyme disease. In one preferred embodiment, this invention provides modified OspA polypeptides and pharmaceutically effective compositions and methods comprising those polypeptides. A preferred modified OspA polypeptide is set forth in FIG. 1, below. Preferred modified OspA polypeptides are characterized by modifications which diminish and/or ablate their ability to bind the human MHC allele DRB*0401.
    Type: Application
    Filed: March 20, 2001
    Publication date: April 4, 2002
    Inventors: Brigitte T. Huber, Theresa Willett, Abbie Meyer, Dawn Gross