Patents by Inventor Daxin OU

Daxin OU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Drug inclusion complex, preparation thereof, and preparation method thereof
    Patent number: 11071737
    Abstract: A pharmaceutical composition comprises an active component KX2-361 represented by formula 1 or a medicinal salt thereof and hydroxylpropoxyl-?-cyclodextrin. An inclusion compound is formed by KX2-361 or the medicinal salt thereof and hydroxylpropoxyl-?-cyclodextrin, and the solubility of the poorly-soluble drug KX2-361 is improved. The pharmaceutical composition can be prepared into an intravenous preparation and an oral preparation.
    Type: Grant
    Filed: December 20, 2016
    Date of Patent: July 27, 2021
    Assignee: GUANGZHOU XIANGXUE PHARMACEUTICAL CO., LTD.
    Inventors: Shuiping Shi, Qingyong Zhang, Ronghua Zhao, Huihong Chen, Lun Zeng, Daxin Ou, Yan Liu
  • Oral preparation and preparation method thereof
    Patent number: 11007141
    Abstract: An oral preparation for treating cell proliferation diseases. The oral preparation comprises hydroxylpropoxyl-?-cyclodextrin and an active component. The active component is KX2-361 or a medicinal salt thereof, and KX2-361 is represented by formula 1. By mixing hydroxylpropoxyl-ydcyclodextrin with KX2-361 or the medicinal salt thereof, an inclusion complex is formed, the solubility of the poorly-soluble drug KX2-361 is greatly improved, and accordingly the drug is prepared into an oral preparation. The oral preparation has good stability, high safety, good absorbability, high bioavailability and economical cost.
    Type: Grant
    Filed: December 20, 2016
    Date of Patent: May 18, 2021
    Assignees: GUANGZHOU XIANGXUE PHARMACEUTICAL CO., LTD., HANGZHOU CONVERD CO., LTD.
    Inventors: Shuiping Shi, Qingyong Zhang, Ronghua Zhao, Huihong Chen, Lun Zeng, Daxin Ou, Yan Liu
  • DRUG INCLUSION COMPOUND, PREPARATION THEREOF, AND PREPARATION METHOD THEREOF
    Publication number: 20190000859
    Abstract: A pharmaceutical composition comprises an active component KX2-361 represented by formula 1 or a medicinal salt thereof and hydroxylpropoxyl-?-cyclodextrin. An inclusion compound is formed by KX2-361 or the medicinal salt thereof and hydroxylpropoxyl-?-cyclodextrin, and the solubility of the poorly-soluble drug KX2-361 is improved. The pharmaceutical composition can be prepared into an intravenous preparation and an oral preparation.
    Type: Application
    Filed: December 20, 2016
    Publication date: January 3, 2019
    Inventors: Shuiping SHI, Qingyong ZHANG, Ronghua ZHAO, Huihong CHEN, Lun ZENG, Daxin OU, Yan LIU
  • ORAL PREPARATION AND PREPARATION METHOD THEREOF
    Publication number: 20190000756
    Abstract: An oral preparation for treating cell proliferation diseases. The oral preparation comprises hydroxylpropoxyl-?-cyclodextrin and an active component. The active component is KX2-361 or a medicinal salt thereof, and KX2-361 is represented by formula 1. By mixing hydroxylpropoxyl-ydcyclodextrin with KX2-361 or the medicinal salt thereof, an inclusion complex is formed, the solubility of the poorly-soluble drug KX2-361 is greatly improved, and accordingly the drug is prepared into an oral preparation. The oral preparation has good stability, high safety, good absorbability, high bioavailability and economical cost.
    Type: Application
    Filed: December 20, 2016
    Publication date: January 3, 2019
    Applicants: GUANGZHOU XIANGXUE PHARMACEUTICAL CO., LTD., HANGZHOU CONVERD CO., LTD.
    Inventors: Shuiping SHI, Qingyong ZHANG, Ronghua ZHAO, Huihong CHEN, Lun ZENG, Daxin OU, Yan LIU