Patents by Inventor Dazheng Wu

Dazheng Wu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for detecting therapeutic effects of anti-cancer drugs by monitoring changes in gut flora
    Patent number: 8097417
    Abstract: Non-invasive methods for monitoring the effect of an agent for treating colorectal cancer, comprising (1) collecting fecal samples from healthy subjects, subjects having precancerous lesions, and subject having precancerous lesions and being treated with an anti-cancer agent; (2) isolating total microbial genomic DNA from the fecal samples to provide total microbial genomic DNA; (3) comparing the total microbial genomic DNA using fingerprint spectrum analysis; (4) identifying key fingerprint bands correlated with the effect of the anti-cancer agent; (5) identifying key microorganisms associated with the key fingerprint bands; (6) designing microbial sequence-specific primers and probes; and (7) determining the quantitative differences of the key microorganisms in fecal samples to identify an indicator microorganism for monitoring the effect of the anti-cancer agent.
    Type: Grant
    Filed: February 23, 2009
    Date of Patent: January 17, 2012
    Inventors: Liping Zhao, Wei Hua, Xiaoyan Pang, Jia Wei, Dazheng Wu
  • Methods for detecting therapeutic effects of anti-cancer drugs
    Publication number: 20100112564
    Abstract: precancerous lesions, and subject having precancerous lesions and being treated with an anti-cancer agent; (2) isolating total microbial genomic DNA from the fecal samples to provide total microbial genomic DNA; (3) comparing the total microbial genomic DNA using fingerprint spectrum analysis; (4) identifying key fingerprint bands correlated with the effect of the anti-cancer agent; (5) identifying key microorganisms associated with the key fingerprint bands; (6) designing microbial sequence-specific primers and probes; and (7) determining the quantitative differences of the key microorganisms in fecal samples to identify an indicator microorganism for monitoring the effect of the anti-cancer agent.
    Type: Application
    Filed: February 23, 2009
    Publication date: May 6, 2010
    Applicant: Shanghai Jiao Tong University
    Inventors: Liping Zhao, Wei Hua, Xiaoyan Pang, Jia Wei, Dazheng Wu