Patents by Inventor Dazhi Yang

Dazhi Yang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250082668
    Abstract: Covalently cross-linked copolymers are described herein. More specifically, polysaccharide-polyamine copolymeric matrices or structures and cationic copolymeric matrices are described herein. The polysaccharide-polyamine copolymers, when protonated, can form cationic copolymeric matrices having exceptionally high densities of cationic sites. In one form, the covalently cross-linked copolymers provide a three-dimensional structure, especially when hydrated.
    Type: Application
    Filed: November 26, 2024
    Publication date: March 13, 2025
    Applicant: Howard University
    Inventors: James W. MITCHELL, Dazhi YANG
  • Patent number: 12186336
    Abstract: Covalently cross-linked copolymers are described herein. More specifically, polysaccharide-polyamine copolymeric matrices or structures and cationic copolymeric matrices are described herein. The polysaccharide-polyamine copolymers, when protonated, can form cationic copolymeric matrices having exceptionally high densities of cationic sites. In one form, the covalently cross-linked copolymers provide a three-dimensional structure, especially when hydrated.
    Type: Grant
    Filed: October 22, 2020
    Date of Patent: January 7, 2025
    Assignee: Howard University
    Inventors: James W. Mitchell, Dazhi Yang
  • Publication number: 20220259306
    Abstract: Provided are an antibody targeting NKG2A, a preparation method therefor and use thereof. Specifically, provided is a new mouse or humanized monoclonal antibody targeting NKG2A, and a method for preparing the monoclonal antibody. The monoclonal antibody can bind to an NKG2A antigen with high specificity, and has high affinity and significant activities such as anti-tumor activity.
    Type: Application
    Filed: November 6, 2019
    Publication date: August 18, 2022
    Inventors: Qing DUAN, Lile LIU, Dazhi YANG, Jing GAO, Lili HU, Ruirui SUI, Dongxu WANG, Ye HAN, Rongrong XIE, Yan LU, Xiaohui SHAO, Jie ZHANG, Wenming ZHOU, Cuicui GUO, Guozhen TONG, Lina WANG, Chaohui DAI, Mengying WANG
  • Patent number: 10925893
    Abstract: Disclosed is a pharmaceutical composition for treating hypercholesterolemia. The pharmaceutical composition includes a polysaccharide-polyamine copolymer and a pharmaceutically acceptable salt thereof as active ingredients.
    Type: Grant
    Filed: March 18, 2016
    Date of Patent: February 23, 2021
    Inventor: Dazhi Yang
  • Publication number: 20210038638
    Abstract: Covalently cross-linked copolymers are described herein. More specifically, polysaccharide-polyamine copolymeric matrices or structures and cationic copolymeric matrices are described herein. The polysaccharide-polyamine copolymers, when protonated, can form cationic copolymeric matrices having exceptionally high densities of cationic sites. In one form, the covalently cross-linked copolymers provide a three-dimensional structure, especially when hydrated.
    Type: Application
    Filed: October 22, 2020
    Publication date: February 11, 2021
    Applicant: HOWARD UNIVERSITY
    Inventors: James W MITCHELL, Dazhi YANG
  • Patent number: 10849927
    Abstract: Covalently cross-linked copolymers are described herein. More specifically, polysaccharide-polyamine copolymeric matrices or structures and cationic copolymeric matrices are described herein. The polysaccharide-polyamine copolymers, when protonated, can form cationic copolymeric matrices having exceptionally high densities of cationic sites. In one form, the covalently cross-linked copolymers provide a three-dimensional structure, especially when hydrated.
    Type: Grant
    Filed: March 18, 2016
    Date of Patent: December 1, 2020
    Assignee: HOWARD UNIVERSITY
    Inventors: James W. Mitchell, Dazhi Yang
  • Patent number: 10723809
    Abstract: Microcarriers, matrices and scaffolds for growing mammalian cells are provided which include copolymer particles and matrices comprising of polysaccharide-polyamine copolymers. The copolymeric particles and matrices have a pore size of at least 50 microns and permit the mammalian cells to grow both on an exterior surface of the particles and matrices and within an interior of the particles and matrices. Methods for making such microcarriers, matrices and scaffolds, and compositions are also provided. Methods for growing mammalian cells utilizing such microcarriers, matrices and scaffolds and compositions are also provided.
    Type: Grant
    Filed: March 18, 2016
    Date of Patent: July 28, 2020
    Assignee: HOWARD UNIVERSITY
    Inventors: James W. Mitchell, Dazhi Yang
  • Patent number: 10639325
    Abstract: Disclosed is a pharmaceutical composition for treating hyperuricemia (HUA). The pharmaceutical composition includes a polysaccharide-polyamine copolymer and a pharmaceutically acceptable salt thereof as active ingredients.
    Type: Grant
    Filed: March 18, 2016
    Date of Patent: May 5, 2020
    Inventor: Dazhi Yang
  • Publication number: 20200048452
    Abstract: The invention is a polyoxymethylene film and a preparation method. The polyoxymethylene film comprises: 96 to 98 parts by weight of polyoxymethylene resin, 0.5 to 2 parts by weight of nucleating agent, 0.5 to 1 parts by weight of antioxidant, and 0.5 to 1 parts by weight of formaldehyde absorbent. In view of the high crystallinity and fast crystallization rate of polyoxymethylene, blown film process is used to directly blowing the molten mass extruded through a die of a screw extruder to form a blown film bubble. It is easy to form thin neck and easy to break when stretching, so the method is beneficial to form polyoxymethylene film, and has high processing efficiency, and is suitable for industrialization. Copolymerization unit —CH2—CH2—O— is introduced into the molecular chain of polyoxymethylene and its ratio is increased, thereby effectively reducing the crystallization rate of the materials and making it easier to form a film.
    Type: Application
    Filed: September 8, 2019
    Publication date: February 13, 2020
    Inventors: Yatao WANG, Xiaofeng MA, Jianhua LI, Lili LIU, Xuehua GUO, Hongjuan LI, Wang JIN, Dazhi YANG, Lizheng GUAN
  • Patent number: 9998440
    Abstract: A system for an electronic authentication client and a processing method thereof, and a system for electronic authentication and a method thereof are disclosed.
    Type: Grant
    Filed: September 12, 2014
    Date of Patent: June 12, 2018
    Assignee: Tencent Technology (Shenzhen) Company Limited
    Inventors: Yu Yan, Dazhi Yang, Wen Zhang, Bin Ma
  • Publication number: 20180110801
    Abstract: Disclosed is a pharmaceutical composition for treating hyperuricemia (HUA). The pharmaceutical composition includes a polysaccharide-polyamine copolymer and a pharmaceutically acceptable salt thereof as active ingredients.
    Type: Application
    Filed: March 18, 2016
    Publication date: April 26, 2018
    Inventor: Dazhi YANG
  • Publication number: 20180099007
    Abstract: Covalently cross-linked copolymers are described herein. More specifically, polysaccharide-polyamine copolymeric matrices or structures and cationic copolymeric matrices are described herein. The polysaccharide-polyamine copolymers, when protonated, can form cationic copolymeric matrices having exceptionally high densities of cationic sites. In one form, the covalently cross-linked copolymers provide a three-dimensional structure, especially when hydrated.
    Type: Application
    Filed: March 18, 2016
    Publication date: April 12, 2018
    Applicant: Howard University
    Inventors: James W. Mitchell, Dazhi Yang
  • Publication number: 20180094080
    Abstract: Microcarriers, matrices and scaffolds for growing mammalian cells are provided which include copolymer particles and matrices comprising of polysaccharide-polyamine copolymers. The copolymeric particles and matrices have a pore size of at least 50 microns and permit the mammalian cells to grow both on an exterior surface of the particles and matrices and within an interior of the particles and matrices. Methods for making such microcarriers, matrices and scaffolds, and compositions are also provided. Methods for growing mammalian cells utilizing such microcarriers, matrices and scaffolds and compositions are also provided.
    Type: Application
    Filed: March 18, 2016
    Publication date: April 5, 2018
    Applicant: Howard University
    Inventors: James W. Mitchell, Dazhi Yang
  • Publication number: 20180071331
    Abstract: Disclosed is a pharmaceutical composition for treating hypercholesterolemia. The pharmaceutical composition includes a polysaccharide-polyamine copolymer and a pharmaceutically acceptable salt thereof as active ingredients.
    Type: Application
    Filed: March 18, 2016
    Publication date: March 15, 2018
    Inventor: Dazhi YANG
  • Publication number: 20150074760
    Abstract: A system for an electronic authentication client and a processing method thereof, and a system for electronic authentication and a method thereof are disclosed.
    Type: Application
    Filed: September 12, 2014
    Publication date: March 12, 2015
    Applicant: Tencent Technology (Shenzhen) Company Limited
    Inventors: Yu Yan, Dazhi Yang, Wen Zhang, Bin Ma
  • Patent number: 8414873
    Abstract: A blood vessel metal stent coating of amidoglucosan polysaccharide loaded with antibody comprises carrier material composed of chitosan and inartificial degradable acidic amidoglucosan polysaccharide and the effective dose of CD133 antibody loaded in the carrier material. The blood vessel metal stent coating is manufactured with self-assemble method to fix the CD133 antibody in the carrier material of the coating. The coating has good biocompatibility, water retention property, flexibility, flush resistance and bio-stability, and can specifically capture the vascular endothelial progenitor cells in human peripheral blood, and differentiate into vascular endothelial cells. The process would accelerate endothelialization to repair injured vessel caused and prevent restenosis and thrombosis efficiently.
    Type: Grant
    Filed: October 10, 2008
    Date of Patent: April 9, 2013
    Inventors: Shixuan Zhang, Jinghan Sui, Hong Zhao, Dazhi Yang
  • Publication number: 20100215712
    Abstract: A blood vessel metal stent coating of amidoglucosan polysaccharide loaded with antibody comprises carrier material composed of chitosan and inartificial degradable acidic amidoglucosan polysaccharide and the effective dose of CD133 antibody loaded in the carrier material. The blood vessel metal stent coating is manufactured with self-assemble method to fix the CD133 antibody in the carrier material of the coating. The coating has good biocompatibility, water retention property, flexibility, flush resistance and bio-stability, and can specifically capture the vascular endothelial progenitor cells in human peripheral blood, and differentiate into vascular endothelial cells. The process would accelerate endothelialization to repair injured vessel caused and prevent restenosis and thrombosis efficiently.
    Type: Application
    Filed: October 10, 2008
    Publication date: August 26, 2010
    Inventors: Shixuan Zhang, Jinghan Sui, Hong Zhao, Dazhi Yang
  • Patent number: D777184
    Type: Grant
    Filed: November 7, 2014
    Date of Patent: January 24, 2017
    Assignee: Tencent Technology (Shenzhen) Company Limited
    Inventors: Guang Yang, Yu Yin, Yecheng Xian, Dazhi Yang, Dan Liu, Junbiao Chen, Yongyu Dai, Ruiyi Xiao, Yang Mo, Chao Hu, Yinglei Liang, Huiling Li, Wei Yan, Qinghua Zhong, Heming Shao
  • Patent number: D783036
    Type: Grant
    Filed: November 7, 2014
    Date of Patent: April 4, 2017
    Assignee: Tencent Technology (Shenzhen) Company Limited
    Inventors: Guang Yang, Yu Yin, Yecheng Xian, Dazhi Yang, Dan Liu, Junbiao Chen, Yongyu Dai, Ruiyi Xiao, Yang Mo, Chao Hu, Yinglei Liang, Huiling Li, Wei Yan, Qinghua Zhong, Heming Shao
  • Patent number: D946002
    Type: Grant
    Filed: December 21, 2020
    Date of Patent: March 15, 2022
    Inventor: Dazhi Yang