Patents by Inventor Dean A. Le

Dean A. Le has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of treating cytotoxic damage
    Patent number: 6503947
    Abstract: The invention features methods of treating cytotoxic damage in a subject comprising administering to the subject a substance which is a complement inhibitor, free radical scavenger, or both, to thereby treat cytotoxic damage. The methods of the invention can be used to treat cytotoxic damage associated with a non-thrombotic or thrombotic condition. Methods of treating thrombotic conditions such as stroke and/or ischemia in a subject, comprise administering a thrombolytic agent and a substance which is a complement inhibitor, free radical scavenger or both.
    Type: Grant
    Filed: January 27, 1999
    Date of Patent: January 7, 2003
    Assignee: Brigham and Women's Hospital
    Inventors: Stuart A. Lipton, Dean Le, Marcus Kaul, Jonathan S. Stamler
  • Carboxyl-terminal protein sequencing method and kit
    Patent number: 5064767
    Abstract: Polypeptides are sequenced from the carboxyl terminus by treating the peptide with an iodoxybenzene, followed by removal of the excess reagent and reaction with 2-aminothiophenol at an elevated temperature. The resulting benzthiazolidine is then analyzed to determine the C-terminal amino acid which has been cleaved. A kit which contains the iodoxybenzene and 2-aminothiophenol reagents is separate containers is also disclosed.
    Type: Grant
    Filed: June 21, 1990
    Date of Patent: November 12, 1991
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Dean A. Le, Kazuhiko Tatemoto