Abstract: A medical balloon comprises a braided construct of a low melting temperature bonding yarn and a high-strength reinforcing yarn. The braided structure is contacted to the outer surface of a polymeric balloon serving as a scaffold and then post-processed in a reflow heating step which elevates the assembly above the melting temperature of the bonding yarn. The reflow heating step causes the bonding yarn to melt and flow over, around and under the reinforcing yarn and over and around the balloon. When the melted bonding yarn is cooled to an ambient temperature, it bonds to the reinforcing yarn and to the outer surface of the balloon.

Abstract: In various examples, a skirt for creating a seal between an implantable vascular device and vascular anatomy of a patient includes a seamless tubular structure. The tubular structure is formed from a textile material. A plurality of protrusions extend radially outwardly from the tubular structure. The protrusions are formed within and integral with the tubular structure. Each protrusion including an initial shape, wherein the protrusions are configured to flatten with pressure applied in a radially inward direction with respect to the tubular structure and recoil with pressure at least partially removed to regain the initial shapes of the protrusions, such that the protrusions conform to the vascular anatomy to create the seal between the implantable vascular device and the vascular anatomy.

Abstract: A heart valve replacement device and methods of manufacturing same are provided. The heart valve replacement device includes a substrate and a low-profile composite covering in conformal contact with the substrate and suturelessly attached to the substrate. The low-profile composite covering includes a textile base layer and a thermoplastic polymer coating integrated with the textile base layer. The thermoplastic polymer coating or select portions thereof are substantially fluid impermeable.

Abstract: A bone implant for enclosing bone material is provided. The bone implant comprises a mesh having one or more pores, an inner surface and an outer surface opposing the inner surface, the inner surface configured to receive a bone material when the inner surface of the mesh is in an open configuration; and a plurality of projections disposed on or in at least a portion of the inner surface of the mesh, the outer surface of the mesh or both the inner surface and outer surface of the mesh.

Abstract: A heart valve replacement device and methods of manufacturing same are provided. The heart valve replacement device includes a substrate and a low-profile composite covering in conformal contact with the substrate and suturelessly attached to the substrate. The low-profile composite covering includes a textile base layer and a thermoplastic polymer coating integrated with the textile base layer. The thermoplastic polymer coating or select portions thereof are substantially fluid impermeable.

Abstract: The present invention provides a steerable medical or surgical device, in particular a steerable catheter having one or more actuators which may be integrated into a catheter without the need for welding the actuator to the catheter, the device comprising a main shaft having a proximal end and a distal end, and at least one braided actuator coupled to the main shaft at or adjacent the distal end.

Abstract: A heart valve replacement device and methods of manufacturing same are provided. The heart valve replacement device includes a substrate and a low-profile composite covering in conformal contact with the substrate and suturelessly attached to the substrate. The low-profile composite covering includes a textile base layer and a thermoplastic polymer coating integrated with the textile base layer. The thermoplastic polymer coating or select portions thereof are substantially fluid impermeable.

Abstract: One aspect of the present disclosure relates to a tissue integration device. The tissue integration device can be produced by forming a polymer mixture into a shape. The polymer mixture can include a polymer resin and a growth-promoting medium. Next, at least one polymer forming the polymer resin can be oriented in at least one direction. The shaped polymeric material can then be formed into the tissue integration device.

Abstract: The present invention provides a steerable medical or surgical device, in particular a steerable catheter having one or more actuators which may be integrated into a catheter without the need for welding the actuator to the catheter, the device comprising a main shaft having a proximal end and a distal end, and at least one braided actuator coupled to the main shaft at or adjacent the distal end.

Abstract: One aspect of the present disclosure relates to a tissue integration device. The tissue integration device can be produced by forming a polymer mixture into a shape. The polymer mixture can include a polymer resin and a growth-promoting medium. Next, at least one polymer forming the polymer resin can be oriented in at least one direction. The shaped polymeric material can then be formed into the tissue integration device.

Abstract: A heart valve replacement and methods of manufacturing same are provided. A heart valve replacement includes a substrate and a low profile composite covering in conformal contact with the substrate and suturelessly attached to the substrate. The low profile composite covering includes a textile base layer and a thermoplastic polymer coating integrated with the textile base layer. The thermoplastic polymer coating or select portions thereof are substantially fluid impermeable.

Abstract: A soft tissue implant comprises a condensed surgical mesh having a plurality of monofilament biocompatible fibers 12. Condensing of the fibers reduces the void space between adjacent fibers 12 in the mesh and reduces the surface area of the fibers 12 available for contact with tissue. Condensation of the fibers 12 may be achieved by applying mechanical pressure, and/or vacuum, and/or heat to the mesh.

Abstract: The present invention features soft tissue implants comprising major and minor struts and methods for making same. The implants can includes a biocompatible film that is rendered porous due to the inclusion of uniformly or non-uniformly patterned cells, and the film has a thickness of less than about 0.015 inches in the event the starting material is non-porous and less than about 0.035 inches in the event the starting material is a microporous film. Multi-film implants can also be made.

Abstract: One aspect of the present disclosure relates to a tissue integration device. The tissue integration device can be produced by forming a polymer mixture into a shape. The polymer mixture can include a polymer resin and a growth-promoting medium. Next, at least one polymer forming the polymer resin can be oriented in at least one direction. The shaped polymeric material can then be formed into the tissue integration device.

Abstract: A medical assembly comprises a soft tissue implant (16) for treating a first portion of body tissue during hernia repair, and a device (20). The device (20) comprises a support element (31) to support the soft tissue implant (16) during deployment. The device (20) comprises an elongate drawstring to releasably couple the soft tissue implant (16) to the support element (31). The support element (31) and the soft tissue implant (16) are movable between a collapsed delivery configuration, and an expanded deployment configuration. During deployment a second end (33) of the support element (31) engages with a second portion of body tissue to maintain the second portion of body tissue spaced-apart from the soft tissue implant (16). The support element (31) comprises an access opening (34) through which one or more instruments may be extended to access the soft tissue implant (16). The soft tissue implant (16) is attached to the first portion of body tissue using a suture.

Abstract: A soft tissue implant comprises a condensed surgical mesh having a plurality of monofilament biocompatible fibres 12. Condensing of the fibres reduces the void space between adjacent fibres 12 in the mesh and reduces the surface area of the fibres 12 available for contact with tissue 18. Condensation of the fibres 12 may be achieved by applying mechanical pressure, and/or vacuum, and/or heat to the mesh.

Abstract: The present invention features soft tissue implants comprising major (34) and minor struts (36) and methods for making same. The implants can include biocompatible film (30) that is rendered porous due to the inclusion of uniformly or non-uniformly patterned cells (32), and the film has a thickness of less than about (0.015 inches) in the event the starting material is non-porous and less than about (0.035 inches) in the event the starting material is a microporous film. Multi-film implants can also be made.

Abstract: A soft tissue implant comprises a condensed surgical mesh having a plurality of monofilament biocompatible fibres 12. Condensing of the fibres reduces the void space between adjacent fibres 12 in the mesh and reduces the surface area of the fibres 12 available for contact with tissue 18. Condensation of the fibres 12 may be achieved by applying mechanical pressure, and/or vacuum, and/or heat to the mesh.